Clinical trials: Mobility Limitations, open to volunteers
Frailty, Aging
Comprehensive Geriatric Assessment in Primary Care
This study evaluates the feasibility and acceptability of implementing the electronic Comprehensive Geriatric Assessment (eCGA) in primary care for adults aged 65 years and older.
- Conditions
- Frailty, Aging, Geriatric Syndromes, Mobility Limitation
- Trial name
- PC-CGA (NCT07341061)
- Testing
- Personalized Approach for Healthy Aging (PAHA)
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Parkinson Disease, Freezing of Gait
Remote Mental Practice for Freezing of Gait in Parkinson's Disease
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with…
- Trial name
- NCT06957405
- Testing
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Abdominal Surgeries, Mobility Limitation
Validity and Reliability of the Arabic Version of De Morton Mobility Index After Abdominal Surgeries
PURPOSE: To determine validity and reliability of translated Arabic version of the De Morton Mobility index for mobility assessment in patients after abdominal surgeries.
- Conditions
- Abdominal Surgeries, Mobility Limitation, Mobility Difficulty, Abdominal Surgery Patients
- Trial name
- NCT06796218
- Where
- Egypt
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Cairo University
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Gait Disorders
Quantifying Gait Disorders With Wearable Sensors
This is a single-centre, cross-sectional observational study with adjunctive procedure for the healthy voluteers at IRCCS Ospedale San Raffaele's Rehabilitation Department.
- Trial name
- NCT07473141
- Testing
- Gait assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Cerebral Palsy, Musculoskeletal Deformity
Neuromusculoskeletal Modeling of Muscle Spasticity
Cerebral palsy (CP) is a movement and posture disorder caused by an injury to the developing brain, with a prevalence in Sweden of about 2/1000 live births.
- Conditions
- Cerebral Palsy, Musculoskeletal Deformity, Spasticity, Muscle Strength
- Trial name
- NCT05447299
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Region Stockholm
Endometriosis, Mobility Limitation
ENDOMETRIOSIS - MRI
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes…
- Conditions
- Endometriosis, Mobility Limitation, Magnetic Resonance Imaging, Diagnosis
- Trial name
- ENDO-MRI (NCT05779462)
- Testing
- Dynamic MRI Sequence
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Aging, Fall Risk
Implementation of Routine Walking Speed Measurements in Older Veterans
Walking speed is a powerful predictor of mortality and adverse health consequences (e.g. fall or hospitalization) in older adults.
- Conditions
- Aging, Fall Risk, Mobility Limitation
- Trial name
- NCT07513805
- Testing
- Usual Care, FASTER
- Where
- United States
- Volunteers
- 10,500 people
- Sponsor
- VA Office of Research and Development
Cerebral Small Vessel Disease
Neural Correlates (EEG and fMRI) of Gait in Small Vessel Disease
What is the purpose of this study? This observational study is being done to understand how cerebral small vessel disease (SVD) affects walking and balance.
- Trial name
- doesn't exist (NCT07372937)
- Testing
- No Intervention: Observational
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hereditary Multiple Osteochondromas
Functional and Morphological Characterization of Multiple Osteochondromas Disorder
The main purpose of the study is the characterization of functional and morphological alterations due to multiple osteochondromas in a pediatric and adult population through the identification of relevant anthropometric and…
- Trial name
- MAMBO (NCT06703736)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Limitation, Mobility, Older Adults
SuPA Mobility: Supporting Physical Activity for Mobility in Mobility-Limited Older Adults
The goal of this randomized controlled trial is to investigate the effectiveness of a health-coaching intervention to improve physical activity in older adults with limited mobility when compared to a control, health education…
- Trial name
- NCT05978336
- Testing
- Health Coaching Program, Health Education Program
- Where
- Canada
- Volunteers
- 290 people
- Sponsor
- University of British Columbia
Parkinson Disease
Study on Preliminary Safety and Efficacy of Adaptive DBS Aligned to Locomotor States to Improve Locomotor Functions in Parkinson's Patients
At present, there is no cure for Parkinson's disease. The standard treatment involves taking dopaminergic drugs. When drugs lose their effectiveness, they can be supplemented by Deep Brain Stimulation (DBS) therapy.
- Trial name
- AdapGAIT (NCT06791902)
- Testing
- Adaptive DBS
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Jocelyne Bloch
Alzheimers Disease, Mild Cognitive Impairment
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor…
- Trial name
- NCT06484244
- Testing
- 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Mobility Disability, Walking Difficulty
Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults
The goal of this clinical trial is to learn if messages focused on not losing the functional benefits of exercise can help older adults with walking difficulty continue to exercise regularly.
- Trial name
- NCT07540052
- Testing
- Brief Daily At-Home Strength Training Program, Loss Aversion Messaging, Standard Adherence Reminder Messaging
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Milton S. Hershey Medical Center
Sarcoma, Bone, Sarcoma, Soft Tissue
Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients
The goal of DEEPGAIT study is to determine how serious walking problems are for pediatric cancer patients who have had orthopedic surgery, how they change over time, and what can be done to help.
- Conditions
- Sarcoma, Bone, Sarcoma, Soft Tissue, Gait Disorder
- Trial name
- NCT07502885
- Testing
- Lab based 3D Gait Assessment, Wearable Inertial Sensors (In Lab and Remote), Functional Testing & Patient Reported Outcomes
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Hip Fractures, Mobility Limitation
Validation of the French Version of the New Mobility Score (NMS)
The incidence of hip fractures in France is 50,000 cases per year among women and 16,000 among men, with a 1-year mortality rate of 20-24%. After a fracture, 10-30% of patients become functionally dependent.
- Conditions
- Hip Fractures, Mobility Limitation, Independence, Autonomy
- Trial name
- MOB-SCORE (NCT07622095)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Peripheral Arterial Disease, Aging
SMART Exercise for PAD
Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery…
- Conditions
- Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
- Trial name
- NCT06032065
- Testing
- Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
- Where
- 3 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Hemiplegia, Balance Disorders
Effect of Shoulder Sling Use on Balance and Mobility in Subacute Stroke Patients
This study examines whether wearing a shoulder sling can improve balance and mobility in people who are recovering from a stroke.
- Conditions
- Hemiplegia, Balance Disorders, Mobility Limitation, Shoulder Subluxation
- Trial name
- SLS-Stroke (NCT06904768)
- Testing
- Shoulder Sling, No Sling
- Where
- Greece
- Volunteers
- 17 people
- Sponsor
- Arnaoutis Stylianos
Spinal Cord Injury, Ambulation Difficulty
Exoskeleton and Spinal Cord Stimulation for SCI
The overall aim of this project is to assess the effect of combining transcutaneous lumbosacral stimulation (TLS) during Exoskeleton Assisted Walking (EAW) compared to EAW alone without stimulation on walking recovery.
- Conditions
- Spinal Cord Injury, Ambulation Difficulty, Muscle Spasticity
- Trial name
- NCT03096197
- Testing
- Exoskeleton-Assisted Walking, Transcutaneous Lumbosacral Stimulation (TLS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation