Clinical trials: Mobilization
Acute Coronary Syndrome
Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase I
The purpose of this randomized, multi-site, clinical trial is to determine whether intensive therapy consisting of cholesterol-lowering statin drugs plus apheresis to cleanse the blood of low-density lipoprotein (LDL) cholesterol…
- Trial name
- PREMIER (NCT01004406)
- Testing
- intensive LDL-lowering therapy, standard statin monotherapy
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Non-Specific Low Back Pain
Spinal Mobilization and Manipulation for Nonspecific Low Back Pain
Low back pain is one of the most common musculoskeletal disorders worldwide and is a major cause of pain and disability. Manual therapy techniques such as spinal mobilization and spinal manipulation are frequently used together…
- Trial name
- SMM-LBP (NCT07749898)
- Testing
- Spinal Mobilization and Manipulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Chronic Neck Pain
Effectiveness of Manual Myofascial Release Versus Instrument Assisted Soft Tissue Mobilization (IASTM) in Patients With Chronic Neck Pain"
Neck pain has a global prevalence of 30%, being the fourth leading cause of disability among general population and is more prevalent among females than males, as per concluded by evidence.
- Trial name
- NCT05502406
- Testing
- Instrument Assisted Soft tissue Mobilization, Manual Myofascial Release
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Low Back Pain, Pregnancy
Soft Tissue Mobilization for Lumbopelvic Pain in the Third Trimester of Pregnancy
Back pain is one of the most common complaints in pregnancy. It is caused by the growing pregnant abdomen which then strains the lower back and pelvis.
- Trial name
- STM (NCT03433404)
- Testing
- Soft Tissue Mobilization, Soft Tissue Massage
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Hematopoietic Stem Cell Mobilization
Early Prophylactic rhTPO Administration for Thrombocytopenia Associated With EAP Regimen-Based Hematopoietic Stem Cell Mobilization
This is a multicenter, prospective, single-arm, phase II clinical study evaluating the early prophylactic use of recombinant human thrombopoietin (rhTPO) to prevent thrombocytopenia associated with the EAP regimen for…
- Conditions
- Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Hematopoietic Stem Cell Mobilization, Chemotherapy-Induced Thrombocytopenia
- Trial name
- NCT07848672
- Testing
- rhTPO prophylaxis plus EAP stem-cell mobilization
- Volunteers
- 70 people
- Sponsor
- The Affiliated People's Hospital of Ningbo University
Ischemic Congestive Heart Failure (CHF)
Stem Cell Mobilization and VEGF Gene Transfer for Heart Failure
The purpose of this study is to evaluate the safety and bioactivity of intramyocardial gene transfer using VEGF (vascular endothelial growth factor) in patients with ischemic heart failure.
- Trial name
- NCT00279539
- Testing
- Vascular Endothelial Growth Factor (VEGF1)
- Sponsor
- Losordo, Douglas, M.D.
Carpal Tunnel Syndrome, Neurodynamic Treatment
Mechanisms of Neurodynamic Treatments
INTRODUCTION: Carpal tunnel syndrome (CTS) is a relatively common condition caused by compression of one of the main nerves at the wrist, the median nerve.
- Conditions
- Carpal Tunnel Syndrome, Neurodynamic Treatment, Nerve Mobilisation, Diffusion MRI
- Trial name
- MONET (NCT05859412)
- Testing
- Neurodynamic exercises, Steroid injection (Depomedrone 40mg), Advice
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Ischemic Stroke, Haemorrhagic Stroke
The Effects of Posture on Cerebral Blood Flow Velocity During the Acute Phase of Stroke
After stroke, blood vessels in the brain can become damaged, and the brain's ability to control blood flow can be impaired. The brain therefore may be less able to maintain a healthy level of blood flow during challenges such as…
- Conditions
- Ischemic Stroke, Haemorrhagic Stroke, Cerebrovascular Accident, Acute Stroke
- Trial name
- NCT04972812
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Sheffield Hallam University
Pain, Shoulder, Adhesion; Shoulder
Effects of IASTM in the Treatment of Adhesive Capsulitis
This study aimed to determine the effects of IASTM in combination with exercise in frozen shoulder. Thirty-five patients with phase II frozen shoulder included in this single-blind, randomized study.
- Conditions
- Pain, Shoulder, Adhesion; Shoulder, Myofacial Pain
- Trial name
- NCT05358730
- Testing
- Standard Exercise, Instrument Assisted Soft Tissue Mobilization (IASTM), Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Myocardial Ischemia
ACT34-CMI -- Adult Autologous CD34+ Stem Cells (Follow-Up Study)
The purpose of this 12-month, observational, follow-up study is to collect additional data (by telephone contact) with which to assess the efficacy, safety, and effects of intramyocardial injections of adult autologous CD34+…
- Trial name
- NCT00545610
- Where
- 23 sites in United States
- Volunteers
- 150 people
- Sponsor
- Lisata Therapeutics, Inc.
Rotator Cuff Tendinitis
Effect of Cervical Mobilization on Rotator Cuff Tendinitis
this study aimed to investigate the effect of 3 types of cervical mobilization on the strength of shoulder abductors, external rotators and pain level in patient with rotator cuff tendinitis.
- Trial name
- NCT04703660
- Testing
- cervical mobilization
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Noha Elserty
Chemotherapy Induced Peripheral Neuropathy (CIPN), Cancer
Effect of GMI With and Without NM on LE in Cancer Patients With CIPN
The goal of this interventional study is to learn if graded motor imagery with or without added neural mobilization can treat chemotherapy induced nerve related symptoms in lower limbs of cancer patients.
- Trial name
- CIPN (NCT07712302)
- Testing
- Graded Motor Imagery, Neural Mobilization
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
Aging Problems
Effects and Dose-response of Manual Therapy in the ROM of the Ankle in Older People
Limitations of the joint range of the ankle in elderly people is usually common. One of the ways to treat this limitation is through manual therapy, although the effects it produces in dose-response terms are still not well…
- Trial name
- ANKLE_ROM (NCT03600402)
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Critical Ill Patients, Ventilated Patients
Closed-loop Versus Conventional Ventilation Mode During Mobilization Period in Critical Care Patients
Nursing is essential in critically ill patients care but with high risk of hypoxia, especially during mobilization. Full closed-loop control ventilation is well established for her safety in unselected ventilated critical care…
- Trial name
- I-Nursing (NCT03176329)
- Testing
- Nursing 1 : INTELLIVENT-ASV, Nursing 2 : INTELLIVENT-ASV, Nursing 1 : Conventional mode
- Where
- France
- Volunteers
- 267 people
- Sponsor
- Hopital of Melun
Back Pain
Comparative Effects of Soft Tissue Mobilization and Pressure Therapy With and Without Dynamic Cupping on on Pain and Disability in Patients With Thoracic Back Pain.
This study aims to compare the sequential effects of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Transverse Oscillatory Pressure (TOP), with and without Directional Dynamic Cupping, in patients with thoracic back…
- Trial name
- NCT07892066
- Testing
- Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP), Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Management and Technology Lahore
Cervical Radiculopathy
Effects of Thoracic Mobility Versus Stretching Exercise Program in Patients of Cervical Radiculopathy
The study will be a randomized clinical trial with a sample size of 44 to determine the effects of thoracic mobility versus thoracic stretching exercises on pain, range of motion, and function in patients with cervical…
- Trial name
- NCT05404646
- Testing
- Thoracic mobility exercises with conventional physical therapy for cervical radiculopathy, Thoracic stretching exercises with conventional physical therapy for cervical radiculopathy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Sports Physical Therapy
Instrument-assisted Soft Tissue Mobilization in CrossFitters
Objective. To determine the effectiveness of instrument assisted soft tissue mobilization and horizontal adduction stretch in CrossFit practitioners' shoulders.
- Trial name
- MJ-IASTM (NCT03830346)
- Testing
- Instrument-assisted
- Where
- Spain
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Real Fundación Victoria Eugenia
Non Specific Neck Pain
Effects of Cervical SNAGs With and Without Thoracic Manipulation on Neck Pain and Disability in Smartphone Users
Non-specific neck pain is a pain and discomfort in the cervical spinal area that arises without trauma, clearly identifiable pathological cause such as fracture infection, nerve root compression, inflammatory disease or serious…
- Trial name
- NCT07909759
- Testing
- Cervical SNAGS and thoracic manipulation with conventional physiotherapy, Cervical SNAG Mobilization Alone + Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Management and Technology Lahore
Diabetic Peripheral Neuropathy Type 2
Neural Mobilization vs Cervical Neuromodulation in DPN
This study is a three-arm, assessor-blinded, randomized controlled pilot feasibility trial. The primary goal is to evaluate the feasibility and acceptability of conducting a full-scale randomized controlled trial (RCT) comparing…
- Trial name
- NCT07537270
- Testing
- Manual Neural Mobilization, Cervical Neuromodulatory Intervention, Standard Care
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Abeer Abdrabo
Piriformis Syndrome
Effects of Hold Relax With Agonist Contraction and Active Release Therapy on Clinical Outcomes in Piriformis Syndrome
The aim of this study is to compare the effects of hold relax agonist contraction and active release therapy on reducing pain intensity, improving functioning and sleep quality in patient with piriformis syndrome.
- Trial name
- NCT05370378
- Testing
- Hold Relax with Agonist Contraction, Active Release Therapy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- University of Lahore
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