Clinical trials: Moderate or Severe Nasolabial Folds
Moderate or Severe Nasolabial Folds
Effectiveness and Safety Comparison of Lunaphil Ultra (Hyaluronic Acid, by Espad Pharmed Co.) Versus Juvederm Ultra 4® (Hyaluronic Acid, by Allergan Co.) in Nasolabial Folds (NLFs) Management
Rationale and background: Skin aging is a complex process that results in various changes in the skin, including wrinkles, sun spots, and sagging skin.
- Trial name
- NCT06509477
- Testing
- Hyaluronic acid Lunaphil Ultra (by Espad Pharmed Co.), Hyaluronic acid Juvederm Ultra 4® (by Allergan Co.)
- Where
- Iran
- Volunteers
- 104 people
- Sponsor
- Espad Pharmed
Moderate to Severe Nasolabial Folds
Saypha® Volume LIdocaine in Nasolabial Folds
Comparison of saypha Volume Lidocaine from 2 different manufacturing locations in correcting moderate to sever nasolabial folds
- Trial name
- SAVINO (NCT04883632)
- Testing
- Saypha Volume Lidocaine
- Where
- 3 sites in Austria
- Volunteers
- 110 people
- Sponsor
- Croma-Pharma GmbH
Correction of Moderate to Severe Nasolabial Folds (NLFs)
Evaluation of the Effectiveness and Safety of Radiesse for the Correction of Moderate to Severe Nasolabial Folds
Effectiveness: The purpose of this study is to demonstrate the non-inferiority of Radiesse (CaHA) to Restylane (HA) following subdermal implantation for the correction of moderate to severe facial wrinkles and folds, such as…
- Trial name
- NCT04647721
- Testing
- Radiesse injectable implant (dermal filler), Restylane injectable implant (dermal filler)
- Where
- 7 sites in China
- Volunteers
- 134 people
- Sponsor
- Merz North America, Inc.
Correction of the Moderate to Severe Nasolabial Folds
Evaluation of the Effectiveness and Safety of Radiesse for the Correction of Nasolabial Folds in China
The objectives of this study are to evaluate the effectiveness and safety of Radiesse for the correction of nasolabial folds (NLFs).
- Trial name
- NCT03282357
- Testing
- Radiesse injectable implant (dermal filler), Restylane injectable implant (dermal filler)
- Where
- 4 sites in China
- Volunteers
- 181 people
- Sponsor
- Merz North America, Inc.
Correction of Moderate to Severe Nasolabial Folds
Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds
Demonstrate the effectiveness of Belotero Balance with lidocaine (Test group) for the reduction of injection-related pain in comparison to Belotero Balance without lidocaine (Control group) for the correction of NLFs.
- Trial name
- NCT03319719
- Testing
- Belotero® Balance with integral lidocaine, Belotero® Balance
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Merz North America, Inc.
Moderate to Severe Nasolabial Folds
A Safety and Effectiveness Study of JUVÉDERM VOLIFT® XC Versus Control for Moderate to Severe Nasolabial Folds
A prospective, multicenter, within-subject controlled study of the safety and effectiveness of JUVÉDERM VOLIFT® XC versus Control for the correction of moderate to severe nasolabial folds (NLFs).
- Trial name
- NCT01976663
- Testing
- JUVEDERM VOLIFT® XC, Control
- Where
- 7 sites in United States
- Volunteers
- 126 people
- Sponsor
- Allergan
Moderate to Severe Nasolabial Folds
Post-Market Study of JUVÉDERM VOLIFT™ With Lidocaine for the Correction of Nasolabial Folds
A prospective, open-label, multi-center, observational, post-market study evaluating JUVÉDERM VOLIFT™ for the correction of moderate to severe nasolabial folds
- Trial name
- NCT01680497
- Testing
- Crosslinked hyaluronic acid dermal filler
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Allergan