Clinical trials: Modified Radical Mastectomy
Local Anesthetic
Infusion of a Local Anaesthetic in the Surgical After Modified Radical Mastectomy With Expander
Background: The use of local anesthetics as a supplement to conventional techniques in breast surgery is widely reported in the literature.
- Trial name
- NCT01389934
- Testing
- levo-bupicaine
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Basque Health Service
EFFECT OF TOPICAL APPLICATION OF TRANEXAMIC ACID ON WOUND DRAINAGE POST MODIFIED RADICAL MASTECTOMY
EFFECT OF TOPICAL APPLICATION OF TRANEXAMIC ACID ON WOUND DRAINAGE POST MODIFIED RADICAL MASTECTOMY
Objective: To compare efficacy of topical tranexamic acid versus standard postop care in reducing wound drainage following modified radical mastectomy (MRM). Study Design: Randomized controlled trial.
- Trial name
- NCT07800832
- Testing
- Tranexamic Acid (Topical Application in Mastectomy Wound)
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Gulab Devi Hospital
Mammary Cancer
Open Technique Interpectoral Catheter for Postoperative Analgesia in Modified Radical Mastectomy
patients undergoing modified radical mastectomy were divided into two groups. patients in catheter group were placed a catheter with open technique by the surgeon in the pectoral area.
- Trial name
- NCT03204708
- Testing
- catheter, iv analgesia
- Volunteers
- 86 people
- Sponsor
- Istanbul University
Breast Cancer, Post Operative Pain
Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine versus dexamethasone to levobupivacaine in ultrasound guided ESPB for patients undergoing modified radical mastectomy
- Trial name
- NCT05447949
- Testing
- Adjuncts to levobupivacaine in Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery
Comparative study of ketamine added to bupivacaine in PECS block versus topical wound instillation on post operative analgesia in modified radical mastectomy surgery
- Trial name
- NCT05410158
- Testing
- Ketamine in PECS block versus topical wound instillation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postmastectomy Pain
SPSIP Block in Breast Surgeries for Postoperative Analgesia
The aim of this clinical study is to demonstrate that pain following breast surgeries can be reduced through the application of serratus posterior superior intercostal plane block (SPSIPB).
- Trial name
- SPSIPB (NCT06100419)
- Testing
- serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Acute and Chronic Pain Following Modified Radical Mastectomy
Comparison of Oral Lamotrigine Versus Pregabalin for Control of Acute and Chronic Pain
Breast cancer is the most frequent neoplastic tumor in women, and surgical treatment is indicated in most patients. Complications related to this treatment, such as post-mastectomy pain syndrome (PMPS), a persistent pain that…
- Trial name
- NCT03419949
- Testing
- oral lamotrigine 100 mg, oral pregabalin 150 mg
- Where
- Egypt
- Sponsor
- Assiut University
Post Operative Pain
Ketamine Versus Neostigmine as Adjuvants to Bupivacaine During Ultrasound-guided Serratus Anterior Block
This study is designed to investigate the analgesic efficacy of ketamine compared to neostigmine as adjuvants to LA in ultrasound guided Serratus Anterior Plane Block (SAPB) in patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT05802979
- Testing
- Adjuvants, Anesthesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Anaesthesia
Comparing Post-operative Analgesia After (PECS II) Block and (ESPB) in Modified Radical Mastectomy
The aim of this study is to compare the analgesic efficacies of the modified pectoral plane block (PECS II) and the erector spinae plane block (ESPB) after modified radical mastectomy surgery through assessment of post-operative…
- Trial name
- NCT06714682
- Testing
- Modified Pectoral Plane block group, Erector spinae plane block group.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Analgesia
Analgesic Protocol With Gabapentin Dexmedetomidine For Postoperative Pain Managment
Assessment of quality of post mastectomy analgesic protocol of Gabapentin and Dexmedetomedine in a placebo-controlled study
- Trial name
- NCT04976374
- Testing
- Dexmedetomidine and Gabapentin, Saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute, Egypt
Analgesia
Open Versus Ultrasound Approach for Serratus Anterior Block
Ultrasound-guided Serratus anterior plane (SAP) block is an interventional technique that recently gained popularity in the context of postoperative analgesia after breast surgery.
- Trial name
- NCT04841564
- Testing
- ultrasound approach of serratus anterior block, open approach of serratus anterior block
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Mansoura University
Postoperative Pain, Breast Cancer
RISS Versus SPSIP Block in Modified Radical Mastectomy
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior…
- Trial name
- RSMRM (NCT07659990)
- Testing
- Rhomboid Intercostal-Subserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Anesthesia Awareness
TIVA vs Inhalational Mode of Anaesthesia
Sevoflurane based inhalational anaesthesia is the preferred mode of anesthesia for small duration cases. But in recent times, concept of rapid discharge, day care procedures, and green environment has created the need of new…
- Trial name
- NCT03807297
- Testing
- Injection dexmedetomidine, Injection, Propofol, 10 Mg, sevoflurane
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
ESPB, Mg Sulfate,Post Mastectomy
Efficacy of Magnesium Sulfate as an Adjuvant in Erector Spinae Plane Block as an Anesthetic Post Operative After Modified Radical Mastectomy
efficacy of magnesium sulfate as an adjuvant in erector spinae plane block as an anesthetic post-operative after modified radical mastectomy
- Trial name
- NCT05976464
- Testing
- Magnesium sulfate in erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Analgesia, Pain, Postoperative
Superficial Serratus Plane Block for Modified Radical Mastectomy and Axillary Lymph Node Disection
Breast cancer is the most common type of cancer in women. Mastectomy and axillary lymph node disection are commonly performed as part of the cancer management. This surgery can cause significant postoperative pain.
- Conditions
- Postoperative Analgesia, Pain, Postoperative, Opioid Consumption
- Trial name
- NCT03341234
- Testing
- Bupivacaine, Saline, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Breast Cancer
The Effect of Mindfulness-based Yoga and Meditation on Some Parameters in Breast Cancer Patients
The purpose of this study was to evaluate the effect of mindfulness-based meditation and yoga on stress, self-esteem, body image and sexual adjustment in breast cancer patients.
- Trial name
- NCT06110832
- Testing
- Mindfulness-based Meditation and Yoga program
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Pain, Breast Diseases
T3AI-Pain After Breast Surgery
Current standard of care for post-operative analgesia after breast surgery in CDHA is Tylenol #3® (300 mg acetaminophen, 30 mg codeine, 15 mg caffeine per tablet).
- Trial name
- T3AI (NCT00299039)
- Testing
- acetaminophen plus codeine, acetaminophen plus ibuprofen
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer
Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block
Modified radical mastectomy is the most commonly performed surgical approach for breast cancer. The procedure enables surgeons to remove the main tumor mass, adjacent glandular tissue and regional lymph nodes.
- Trial name
- NCT06300099
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Post Operative Pain
Post Operative Pain in Modified Radical Mastectomy.
we will assess post operative pain after surgery of modified radical mastectomy at 12 and 24 hours post operatively on arm movement and on rest
- Trial name
- NCT04620720
- Testing
- capule gabapentin
- Where
- Pakistan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Pain, Postoperative
Analgesic Efficacy of Ultrasound Guided Erector Spinae Block for Modified Radical Mastectomy
To compare the analgesic efficacy of dexmedetomidine and magnesium sulphate as adjuvants to levobupivacaine in erector spinae plane block in modified radical mastectomy surgery for acute and chronic pain management.
- Trial name
- NCT04732364
- Testing
- ultrasound guided erector spinae plan block using bupivacaine for modified radical mastectomy, ultrasound guided erector spinae plan block with bupivacaine and Dexmetonidine for modified radical mastectomy, ultrasound guided erector spinae plan block with bupivacaine and magnesium slphate for modified radical mastectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Egypt Cancer Institute