Clinical trials: Molar, Third
Anxiety, Dental
Virtual Reality Technology on Pain Perception and Anxiety Levels in Adolescents and Young Adults During Third Molar Germ Avulsion Surgery (VIDAMO)
For a long time, the fear of the dental surgeon has been the main reason why a percentage of the population avoids regular consultation.
- Trial name
- VIDAMO (NCT04609956)
- Testing
- Virtual reality, Standard
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain, Postoperative, Edema
Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molars
In dentistry, one of the most common surgical procedures is the removal of included third molars. This surgery generates great morbidity to patients for causing pain, edema and trismus due to surgical trauma.
- Conditions
- Pain, Postoperative, Edema, Trismus, Quality of Life
- Trial name
- NCT03442166
- Testing
- LED group
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Fibrin/Therapeutic Use, Blood Platelets
Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery
The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.
- Conditions
- Fibrin/Therapeutic Use, Blood Platelets, Molar, Third, Bone Regeneration
- Trial name
- NCT02890680
- Testing
- Platelet-rich fibrin, Control group
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Lingual Nerve Injuries
Removal of Impacted Molars With Lingual Split Technique
This research assesses removal of mandibular third molars by the lingual split technique with using Walter's lingual retractor for retracting lingual flap, and evaluates the lingual nerve injury that may result after applying…
- Trial name
- NCT05946317
- Testing
- Lingual nerve function assessed after removal of mandibular third molar with lingual split technique
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Impacted Mandibular Third Molar
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
This randomized controlled clinical trial aims to evaluate the clinical and radiographical effects of the application of a mixture of hyaluronic acid and melatonin after surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07735806
- Testing
- Hyaluronic acid and Melatonin mixture, Gel foam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Wisdom Tooth Removal, Antibiotic Prophylaxis
Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction
The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled.
- Conditions
- Wisdom Tooth Removal, Antibiotic Prophylaxis, Single Dose
- Trial name
- NCT07894016
- Testing
- Amoxicillin 2g, Clindamycin 600 mg, Azithromycin 500mg
- Volunteers
- 105 people
- Sponsor
- Dow University of Health Sciences
Toothache
SB-705498 Dental Pain Study After Tooth Extraction
This clinical trial is a multi centre, randomised, single-blind, parallel group, placebo-controlled, single oral dose study with a positive control arm.
- Trial name
- NCT00281684
- Testing
- SB705498 400 mg, SB705498 1000 mg, Co-Codamol
- Where
- 5 sites in Italy, South Korea and 1 more
- Volunteers
- 145 people
- Sponsor
- GlaxoSmithKline
Dental Pain
Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
The purpose of this study is to assess the activity of buprenorphine hydrochloride (HCl) buccal film in the treatment of dental pain.
- Trial name
- NCT00941304
- Testing
- Oxycodone, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- BioDelivery Sciences International
Wound Heal, Quality of Life
Clinical Wound Healing After Lower 3rd Molar Fully-impacted Surgery With 2 Types of Flap
The dehiscence distal to the second molar after lower third molar extraction is very common because the access flap for surgical extraction cannot be repositioned on a portion of healthy bone to guarantee suture support.
- Conditions
- Wound Heal, Quality of Life, Dehiscence
- Trial name
- NCT04314765
- Testing
- lower third molar extraction
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Impacted Third Molar Tooth
The Effect of Saline Irrigation at Different Temperatures on Pain, Edema, and Trismus After Impacted Third Molar Surgery
Third molar surgery is one of the most common procedures in oral surgery and the most common postoperative complications are swelling, pain, and trismus.
- Trial name
- NCT05170516
- Testing
- 4 °C colled saline irrigation, 10 °C cooled saline irrigation, Room temperature saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Trakya University
Molar, Third, Third Molar Surgery
3D Evaluation of Postoperative Edema After Third Molar Surgery
Surgical removal of third molars is recognized as one of the most frequent procedures performed in oral surgery. Literature is rich in studies attempting to demonstrate the benefit of corticosteroids in third molar surgery…
- Conditions
- Molar, Third, Third Molar Surgery, Soft Tissue Swelling, Pain, Postoperative
- Trial name
- NCT05941130
- Testing
- Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Impacted Mandibular Third Molar
Comparison of Chlorhexidine and Hypochlorous Acid Mouthwash After Impacted Third Molar Surgery
Impacted mandibular third molar extraction is one of the most common procedures in oral and maxillofacial surgery and is frequently associated with postoperative complications such as pain, edema, and trismus, which may…
- Trial name
- NCT07466992
- Testing
- Hypochlorous Acid, Chlorhexidine Gluconate Mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Opioid Use
Opioid Analgesic Reduction Study
The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain management, a double-blind, stratified…
- Trial name
- OARS (NCT04452344)
- Testing
- opioid-containing analgesic, two over-the-counter analgesics
- Where
- 5 sites in United States
- Volunteers
- 1,815 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Third Molar Impaction
The Effect of Different Treatment Modalities of Class II Malocclusion on Upper Third Molars.
What is the effect of the different treatment modalities (distalization versus upper premolar extraction) of class II malocclusion on the position, inclination and incidence of impaction of the upper third molars?
- Trial name
- NCT06098885
- Testing
- extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wisdom Teeth, Oral Surgery
Microbial Growth in the Suture Thread, After Application of Different Antiseptic Gels in Mandibular Third Molars Extraction
This is a randomized clinical trial in which investigators will compare the antimicrobial effect and inducer of cicatrization as well as the degree of postoperative pain in patients who are extracted the lower third molars.
- Conditions
- Wisdom Teeth, Oral Surgery, Third Molar Surgery, Bioadhesive Gel
- Trial name
- NCT03188289
- Testing
- Clorhexidine gel, Clorhexidine-Chitosan gel, Hyaluronic Acid gel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
PRF
The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin)
Objectives: This study aims to evaluate the effects of A-PRF+ on postoperative pain, swelling, and trismus after surgical removal of impacted mandibular third molars.
- Trial name
- A-PRF+ (NCT05824793)
- Testing
- A-PRF+
- Where
- Vietnam
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain, Oral Surgery
Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans
This randomized clinical trial was designed to assess the clinical efficacy of Pulsed electromagnetic field PEMF delivered with a wearable device in terms of postoperative pain and quality of healing after mandibular third molar…
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT02273999
- Testing
- RecoveryRx™
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Impacted Third Molar Tooth
Comparison of Two Different Flap Designs for Bilateral Impacted Mandibular Third Molar Surgery
The aim of this study was to compare the effects of lingually-based triangle flap design and buccally based triangular flap design on postoperative swelling, trismus pain after mandibular third molar surgery.
- Trial name
- NCT03784638
- Testing
- lingually-based triangle flap design, buccally based triangular flap design
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic Acid Which is Widely Used in Medicine for Joint, Eye Care, Wound Healing
Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets
Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars.
- Trial name
- NCT07318298
- Testing
- Surgical extraction of wisdom teeth, bone biobsy
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology