Clinical trials: Molecular Imaging
Gastric Cancer, Molecular Imaging
Novel Humanized Ferritin-based NIR Fluorescent Molecular Probe for Identifying Tumor Margins in Gastric Tissue
Radical surgery remains the primary treatment for gastric cancer, but intraoperative tumor margin assessment relies on surgeons' visual inspection, limiting accuracy.
- Trial name
- NCT07276854
- Testing
- Diagnostic Test: ICG-FTn perfusion solution
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Solid Tumors
TF-antigen Targeting Molecular Probe for PET Imaging in Solid Tumors
The objective of the study is to construct a noninvasive approach using 124I-labeled monoclonal antibody radiotracer to detect the Thomsen-Friedenreich antigen (TF-antigen, CD176) expression of tumor lesions in patients with…
- Trial name
- NCT06755086
- Testing
- 18-FDG
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
Head and Neck Squamous Cell Carcinoma, Margin Assessment
Image Guided Surgery for Margin Assessment of Head and Neck Cancer Using Cetuximab-IRDye800CW cONjugate
Surgery remains a main pillar in the treatment of head and neck squamous cell carcinoma (HNSCC). The margin status is the main prognostic factor of local tumor control in surgically treated HNSCC and will determine the…
- Trial name
- ICON (NCT03134846)
- Testing
- Cetuximab-IRDye800CW
- Where
- Netherlands
- Volunteers
- 79 people
- Sponsor
- University Medical Center Groningen
Breast Abnormalities
The Assessment of Molecular Breast Imaging (MBI) in Distinguishing Benign From Malignant Breast Disease
The primary hypothesis of this project is that using molecular breast imaging (MBI) in evaluating women with equivocal mammographic or sonographic findings will demonstrate high specificity in distinguishing benign from malignant…
- Trial name
- NCT01687790
- Testing
- molecular breast imaging (Discovery)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Parkinson Disease, Nervous System Disorder
Molecular and Functional Imaging in Monogenic PD.
In this study, the investigators aim to find a biomarker of Parkinson's disease. This is done using imaging scans called Positron Emission tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Magnetic…
- Conditions
- Parkinson Disease, Nervous System Disorder, Neurodegenerative Diseases, Neurodegenerative Disease, Hereditary
- Trial name
- FOX_1 (NCT05518617)
- Testing
- Positron Emission Tomography (PET) scan using DASB tracer
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Exeter
Metastatic Breast Cancer (HR+/ HER2-)
Predicting Endocrine Resistance Using Molecular Imaging and Liquid Biopsy in Metastatic Breast Cancer
This prospective observational study aims to evaluate the prognostic value of molecular imaging biomarkers derived from baseline [18F]FES and [18F]FDG PET/CT for progression-free survival in patients with estrogen receptor…
- Trial name
- NCT07867925
- Testing
- [18F] FES
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Stomach Neoplasm, Lymph Node Metastasis
Molecular Imaging of Gastric Cancer Metastatic Lymph Nodes with 99mTc-3PRGD2 Probe.
Surgical lymph node dissection is the key to advanced gastric cancer. In recent years, after the overall implementation of standard D2 dissection, lymph node dissection for gastric cancer began to explore the direction of D1+…
- Conditions
- Stomach Neoplasm, Lymph Node Metastasis, RADIONUCLIDE IMAGING
- Trial name
- NCT06435741
- Testing
- 99mTc-3PRGD2 Spect-CT scan
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Acute Myocardial Infarction (AMI)
Radiolabeled TSPO Targeted Molecular Probe in AMI
Evaluate the clinical application value of the novel radiolabeled TSPO-targeted molecular probe Gallium [68Ga]-DOTA-HK-011 for inflammation imaging associated with acute myocardial infarction.
- Trial name
- NCT07105982
- Volunteers
- 8 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University