Clinical trials: Monitoring, Intraoperative
Laryngeal Nerve, Thyroid Surgery
Neural Monitoring of the Superior Laryngeal Nerve in Thyroid Surgery
Thyroid surgeons place an enormous amount of importance and rightly so to the preservation of the recurrent laryngeal nerve (RLN) during thyroidectomies.
- Trial name
- NCT02395146
- Testing
- Monitoring
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Spinal Cord Associative Plasticity Study
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- SCAP (NCT05163639)
- Testing
- Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hip Fractures, Hypotension on Induction
Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study.
Background During anaesthesia for repair of a broken hip, many patients experience low blood pressure. There have been many studies showing that patients who experience low blood pressure during anaesthesia are at increased risk…
- Conditions
- Hip Fractures, Hypotension on Induction, Intraoperative Hypotension, Acute Kidney Injury
- Trial name
- iSTABILISE (NCT04051073)
- Testing
- Continuous non-invasive blood pressure monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Femoral Neck Fractures
the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index
The investigators aimed to compare the effects of targeted fluid management and traditional fluid management on the inferior vena cava collapsibility index in participants who will undergo proximal femoral surgery.
- Trial name
- NCT05154435
- Testing
- mostcare hemodynamic monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Fluid Therapy, Monitoring, Intraoperative
Assessing Fluid Responsiveness With PWTT
Pulse wave Transit time (PWTT) is a parameter calculated from ECG and pulseoximeter. It is supposed to help assessing the preload Status and guide intraoperative fluid therapy.
- Trial name
- NCT03280953
- Testing
- Assessing fluid responsiveness by PWTT value
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Johannes Gutenberg University Mainz
Esophageal Cancer
Visualization Versus Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerves During Thoracoscopic Esophagectomy
The clinical value of intraoperative nerve monitoring (IONM) in thoracoscopic esophagectomy remains uncertain. The aim of this randomized clinical trial was to compare the impact of RLN visualization versus IONM on their…
- Trial name
- NCT05199168
- Testing
- intraoperative nerve monitoring
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
BIS
Pediatric Frontal and Nasal Bispectral Index
To compare the accuracy of frontal versus nasal BIS monitoring in pediatric patients under general anesthesia.
- Trial name
- NCT06255236
- Testing
- Bispectral index (BIS)
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Bradycardia, Conduction Block, Atrioventricular
LLL vs. SDL for LBBP: A Non-inferiority RCT
Left Bundle Branch Pacing (LBBP) has emerged as one of the most commonly used physiological pacing modalities in clinical practice.
- Trial name
- NCT07378124
- Testing
- SDL implantation, LLL implantation
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Ningbo No.2 Hospital
Cardiac Disease, Cognitive Dysfunction
Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS)
Neurological dysfunction continues to be one of the complications of considerable concern in patients undergoing cardiac surgery.
- Trial name
- COSMICS (NCT04766554)
- Testing
- Cerebral oximetry monitor (The INVOS® Cerebral/Somatic Oximeter) and protocol-based interventions
- Where
- 2 sites in Brazil
- Volunteers
- 326 people
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Neuromuscular Blockade, Muscle Relaxation
Clinical Application of "Train of Four" Testing in the Intraoperative Monitoring Setting
The study examines the clinical application of TOF (train of four test) used by anesthesiologists and neurophysiologists during instrumented spine procedures, as well as certain associated parameters.
- Trial name
- NCT01932983
- Testing
- Train of four test
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Glioma, Motor Pathway
Functional Monitoring for Motor Pathway in Brain Tumor Surgery Within Eloquent Area
Resection of brain tumors in eloquent areas involves the risk of postoperative motor deficits. For brain tumors within or adjacent to the eloquent area, maximizing tumor resection while preserving motor function is crucially…
- Trial name
- NCT01351337
- Testing
- diffusion tensor tractography neuronavigation and intraoperative subcortical stimulation
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Huashan Hospital
Postoperative Delirium, Sevoflurane
Intraoperative EEG Monitoring and Postoperative Delirium in Elderly Patients With Sevoflurane Anesthesia
Delirium is an acute onset of attentional and cognitive impairment. BIS guided anesthesia can reduce the incidence of postoperative delirium.
- Conditions
- Postoperative Delirium, Sevoflurane, Electroencephalogram
- Trial name
- NCT04292561
- Testing
- Low MAC, High MAC
- Where
- China
- Volunteers
- 460 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Postoperative Hypocalcemia, Postoperative Hypoparathyroidism
Ionized Calcium Changes for Predicting Postoperative Hypocalcemia After Total Thyroidectomy
This prospective observational study aims to evaluate whether changes in ionized calcium levels measured by blood gas analysis during the preoperative, intraoperative, and postoperative periods can predict postoperative…
- Conditions
- Postoperative Hypocalcemia, Postoperative Hypoparathyroidism, Total Thyroidectomy
- Trial name
- NCT07701824
- Testing
- Calcium
- Where
- Turkey (Türkiye)
- Volunteers
- 327 people
- Sponsor
- Emrecan Deniz
Epilepsy, Temporal Lobe
The Utility of NIOM During LITT for Refractory MTLE
Mesial temporal lobe epilepsy (MTLE) is the most common cause of medication-resistant epilepsy in adults, and MRI-guided laser interstitial thermal therapy is a new approach to its surgical management; however, while LITT…
- Trial name
- NCT02913742
- Testing
- monitoring by depth electrode
- Where
- United States
- Sponsor
- Duke University