Clinical trials: Monitoring, Intraoperative
Thyroid
Effect of Intraoperative Nerve Monitoring on Voice Quality During Thyroid Surgery
"Effect of intraoperative nerve monitoring on voice quality during thyroid surgery" Thyroidectomy is a quite often surgical procedure applied by both head and neck surgeons and endocrine surgeons.Recent advances in surgical and…
- Trial name
- NCT02509715
- Testing
- Intraoperative nerve monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Cardiac Surgery
IMMPRES: Intraoperative Monitoring & Management to Reduce Stroke
The objective of this study is to prospectively evaluate the therapeutic effectiveness of with blood pressure management using intraoperative neurophysiological monitoring with SSEP and EEG to reduce perioperative stroke.
- Trial name
- NCT04543838
- Testing
- Intervention, Standard of Care BP management
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Parthasarathy Thirumala
Intraoperative Neurophysiological Monitoring
MINDZ-- Minimally Invasive Approach Pilot Study
This clinical investigation is a pilot, first-in-human (FIH) study designed to demonstrate proof of concept, safety, and functional performance of the MINDZ subdural electrode grid when used in relevant neurosurgical settings.
- Trial name
- MINDZ-MAP (NCT07543406)
- Testing
- MINDZ Subdural Electrode Grid
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Neurosoft Bioelectronics SA
Patients Undergoing Total Laparoscopic Hysterectomy
Effect of Intraoperative Nociception Control Based on Analgesia Nociception Index (ANI) Monitoring on Stress Response During Total Laparoscopic Hysterectomy
The "Analgesia Nociception Index" (ANI; MetroDoloris Medical Systems, Lille, France), derived from an electrocardiogram (ECG) trace, has been proposed as a noninvasive guide to analgesia.
- Trial name
- NCT04343638
- Testing
- conventional nociception control, ANI monitor guided nociception control
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Thyroid Surgery
Intra Operative Continuous Laryngeal Nerve Monitoring During Thyroid Surgery and Interpretation of the Post-operative Voice Quality in Relation to the Electromyography Data Obtained During Surgery
During thyroid surgery the laryngeal recurrent nerves (and for this reason the voice quality) are at risk. Therefore intra operative continuous neuromonitoring could help to prevent harm to these nerves.
- Trial name
- CoNeMoTS (NCT01413802)
- Testing
- Continuous nerve monitoring
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Focal Epilepsy, Intraoperative Monitoring
Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid )
The objective of this prospective interventional monocentric clinical investigation is to evaluate the feasibility and performance of the flexible high-density SOFT ECoG electrode grids, manufactured by Neurosoft Bioelectronics…
- Trial name
- EpiGrid (NCT06205160)
- Testing
- SOFT ECoG subdural grid electrode
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Neurosoft Bioelectronics SA
Thyroid Intra-Operative Injury
The Improvement of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve
Objectives: The use of neuromuscular blocking agent may interfere with the function of intraoperative neuromonitoring (IONM) in thyroid surgery.
- Trial name
- NCT03911232
- Testing
- sugammadex
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Intraoperative Hypotension, Hemodynamic Instability
Hypotension Prediction With HPI Algorithm During Major Gynecologic Oncologic Surgery
Intraoperative hypotension (IOH) is a rather common event during general surgery, with variable incidence that ranges between 5 and 99% based on the definition used.
- Conditions
- Intraoperative Hypotension, Hemodynamic Instability, Gynecologic Cancer
- Trial name
- HPI-GOS (NCT04547491)
- Testing
- HPI - hypotension prediction index, GDT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Neuromuscular Blockade, Intraoperative Monitoring
Gentle Skin Abrasion and EMG-Based Neuromuscular Blockade Monitoring
This study will evaluate whether gentle skin abrasion improves electromyographic signal quality during neuromuscular blockade monitoring in adult surgical patients.
- Conditions
- Neuromuscular Blockade, Intraoperative Monitoring, Skin Preparation, Electromyography
- Trial name
- NCT07759206
- Testing
- Gentle Skin Abrasion Before EMG-Based Neuromuscular Blockade Monitoring
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Minnesota
Nociceptive Pain, Pain, Postoperative
Guiding Opioid Administration in Patients With Regional Anesthesia
General anesthesia is a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception.
- Conditions
- Nociceptive Pain, Pain, Postoperative, Analgesia, Anesthesia Recovery Period
- Trial name
- GORA (NCT06040307)
- Testing
- SPI (Surgical Pleth Index)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Obesity
Obesity and Goal-directed Intraoperative Fluid Therapy
The purpose of the study is to compare non-obese patients (BMI≤ 30 kg/m2)versus obese patients (BMI> 30 kg/m2) in regard of their respective needs for intraoperative fluid therapy during laparoscopic surgery.
- Trial name
- NCT01052519
- Testing
- Goal directed fluid therapy
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University of Vienna
Brain Neoplasms
Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery
Gliomas are tumors that occur in all ages; they include the most common malign primary central nervous system tumors in developed countries.
- Trial name
- ATM5-ALA (NCT07111182)
- Testing
- HIVEN Medical Device
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Illinois at Chicago
Spinal Deformity
Spinal Deformity Intraoperative Monitoring.
A multicenter, international prospectively collected patient cohort undergoing high-risk spinal cord level surgery or spinal osteotomy procedures will be enrolled to establish the incidence of intraoperative alerts in high-risk…
- Trial name
- NCT03880292
- Testing
- Document intraoperative Maneuvers
- Where
- 24 sites in United States, Australia and 12 more
- Volunteers
- 592 people
- Sponsor
- AO Foundation, AO Spine
Thyroid Diseases
Different Types of Electrostimulation Probes During IONM
Intraoperative nerve monitoring is often used in many centers during thyroidectomy. According to the investigators' knowledge, there's no study showing superiority between bipolar and monopolar stimulation probes used for nerve…
- Trial name
- NCT03460912
- Testing
- Bipolar and monopolar probes (SPESS MEDICA S.r.l. Via Buccari 16153 Genova (GE), Italy) administered to all participants.
- Volunteers
- 20 people
- Sponsor
- Ege University
Vital Signs
The Use of Portable Wireless Monitor in Patient Vital Sign Monitoring
This clinical investigation assesses the performance of PaMo patient monitor system (PaMo) and its wearable sensing devices that combines continuous IP, ECG and PPG in detecting developing respiratory depression episodes.
- Trial name
- NCT06117111
- Testing
- PaMo monitoring device
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Vestibular Schwannoma, Facial Nerve Paralysis
Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients
The purpose of this study is to evaluate the efficacy and safety of steroids treatment compared with placebo in preserving facial nerve function after craniotomy in patients with vestibular schwannoma who have not received…
- Trial name
- SAF-NRVS (NCT07116811)
- Testing
- Steroids therapy
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Beijing Tiantan Hospital
Intraoperative Blood Loss
Clinical Validation of a Blood Loss Monitoring System
This observational study aims to evaluate the practicality of a novel multifunctional intraoperative blood loss monitoring system in real-world surgical settings.
- Trial name
- NCT07617428
- Where
- 3 sites in China
- Volunteers
- 170 people
- Sponsor
- Lanzhou University Second Hospital
Anesthesia, Monitoring, Intraoperative
Registry Construction of Intraoperative Vital Signs and Clinical Information in Surgical Patients
Monitoring data during anesthesia of surgical patient in the operation room will be collected and stored into the registry automatically. Patients' information and preoperative assessment from medical records will be included.
- Trial name
- NCT02914444
- Where
- South Korea
- Volunteers
- 200,000 people
- Sponsor
- Seoul National University Hospital
Emergence Delirium, Post-Operative Cognitive Dysfunction
Post Operative Cognitive Dysfunction and Delirium After Spinal Surgery
Aim of this trial is to define if Post-Operative Cognitive Dysfunction and Delirium, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, relate to concentration of effector's site…
- Trial name
- NCT03950557
- Volunteers
- 200 people
- Sponsor
- University of Padova
Peripheral Nerve Injuries, Thoracic Surgery
Somatosensory Evoked Potential (SSEP) Monitoring for Detection of Intraoperative Positional Neuropraxia
PNI (Peripheral Nerve Injury) occurs in 5-15% of patients in cardiac surgery. So far, the mechanism of injury has never been researched.
- Trial name
- NCT03422107
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Western University, Canada