Clinical trials: Monogenic Diabetes
Monogenic Diabetes
Incretin Regulation of Insulin Secretion in Monogenic Diabetes
The purpose of this study is to explore the mechanisms of metabolic control in monogenic diabetes patients treated with sulfonylurea medications.
- Trial name
- NCT01795144
- Testing
- GLP-1, Exendin 9-39
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Diabetes Mellitus, Type 1, Immunologic Deficiency Syndromes
Sequential Transplantation of UCBSCs and Islet Cells in Children and Adolescents With Monogenic Immunodeficiency T1DM
This study evaluates the efficacy of sequential transplantation of umbilical cord blood stem cells and islet cells in children with monogenic immunodeficiency type 1 diabetes mellitus.
- Trial name
- NCT03835312
- Testing
- Sequential transplantation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Fudan University
Type1 Diabetes Mellitus
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)
Type 1 diabetes (T1D) results from destruction of insulin-producing beta cells in the pancreas by the body's own immune system (autoimmunity).
- Trial name
- EXE-T1D (NCT03369821)
- Testing
- Beta Cell Loss and Immune Function, Immune Function with RNAseq
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 300 people
- Sponsor
- University of Exeter
Bariatric Surgery Candidate
Abu Dhabi Diabetes and Obesity Study -2 Bariatric
Study on outcomes on bariatric surgery, particularly in terms of metabolic parameters in the UAE is scant. Also Genetic data from this population is limited and hence a study on genetic determinants of response to bariatric…
- Trial name
- ADOS-2B (NCT05140798)
- Where
- United Arab Emirates
- Volunteers
- 1,200 people
- Sponsor
- Imperial College London Diabetes Centre