Clinical trials: Montelukast
Asthma
Short- and Long Term Growth in Children With Asthma
The purpose of this study is to assess if treatment with budesonide 200 microgram per day affects short- or long term growth in children with asthma
- Trial name
- NCT00380484
- Testing
- Budesonide, Montelukast
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Children´s Clinic, Randers
Seasonal Allergic Rhinitis
Montelukast in Seasonal Allergic Rhinitis - Fall 1999 Study (0476A-117)
This study will evaluate the ability of oral montelukast/loratadine to improve the signs and symptoms of seasonal allergic rhinitis compared with loratadine alone, montelukast alone and placebo.
- Trial name
- NCT00963599
- Testing
- Comparator: montelukast/loratadine, Comparator: montelukast, Comparator: loratadine
- Volunteers
- 907 people
- Sponsor
- Organon and Co
Obstructive Sleep Apnea
Effect of Montelukast Therapy in Obstructive Sleep Apnea(OSA) Children
The investigators leading hypotheses are: Oral therapy with montelukast may lead to improved sleep study findings in children with mild to moderate Obstructive Sleep Apnea Syndrome (OSAS) who require surgical removal of adenoids…
- Trial name
- 32543 (NCT01027806)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Chicago
Asthma, COPD
A Pilot Study of Montelukast Sodium (Singulair) in Older Adults With Asthma or Chronic Obstructive Pulmonary Disease
This randomized, double-blind, placebo-controlled trial assessed the efficacy of montelukast in the treatment of adults ≥50 years of age with persistent asthma and/or COPD.
- Trial name
- NCT00162864
- Testing
- montelukast sodium
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
Breast Cancer, Doxorubicin Induced Cardiotoxicity
Effect of Montelukast on Doxorubicin Induced Cardiotoxicity in Breast Cancer
This is a prospective, randomized (1:1) controlled trial that will be carried out on 50 patients who are candidate to evaluate the effect of montelukast on doxorubicin induced cardiotoxicity after 4 cycles of AC.
- Trial name
- NCT05959889
- Testing
- AC protocol, Montelukast
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Damanhour University
Asthma
Pediatric ADVAIR DISKUS Versus Oral Montelukast Chewable Tablets
This study is being conducted to demonstrate the superior clinical effectiveness of Salmeterol/Fluticasone Propionate compared to montelukast in the management of persistent asthma in children aged 6-14 years, and to assess the…
- Trial name
- NCT00328718
- Testing
- montelukast (5mg QD), Salmeterol/Fluticasone propionate Inhalation Powder (50/100mcg BID)
- Where
- 26 sites in Argentina, Colombia and 5 more
- Volunteers
- 526 people
- Sponsor
- GlaxoSmithKline
Sleep Apnea, Obstructive
Montelukast for Patients With Obstructive Sleep Apnea Syndrome
This study compares the effect of Montelukast vs Placebo on Flow Mediated Dilatation of the Brachial Artery (FMD) in patients with obstructive sleep apnea syndrome.
- Trial name
- MONTSAS (NCT03545997)
- Testing
- Montelukast 10mg
- Where
- 8 sites in France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Grenoble
Eosinophilic Esophagitis
Trial of Montelukast in Eosinophilic Esophagitis
Evaluate clinical effectiveness of oral montelukast compared to placebo on prevention of dysphagia and food impaction in patients with EE. Also evaluate tolerance and safety of oral montelukast in treatment of EE.
- Trial name
- NCT00511316
- Testing
- Montelukast/ Singulair
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cough
The Utility of feNO in the Differential Diagnosis of Chronic Cough
In this study the investigators wish to explore the difference in 24 hr. cough counts measured using the Hull Automated Cough Counter (HACC), from baseline and after two weeks treatment with either montelukast or prednisolone in…
- Trial name
- TUF (NCT02479074)
- Testing
- Montelukast (High FeNO group), Prednisolon, Montelukast (High FeNO), Montelukast (Low FeNO group)
- Where
- United Kingdom
- Volunteers
- 49 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Cough, Bronchial Hyperreactivity
The Effect of Montelukast in Patients With Chronic Cough and Bronchial Hyperreactivity
The purpose is to determine whether montelukast during 6 weeks has superior antitussive effects (measured with the LCQ) compared with placebo in patients with cough lasting > 8 weeks and enhanced bronchial hyperreactivity.
- Trial name
- montelukast (NCT00453765)
- Testing
- montelukast
- Where
- Netherlands
- Volunteers
- 89 people
- Sponsor
- Isala
Healthy
A Bioequivalence Study of Montelukast From Asmakast 10mg Tabs (Sandoz, Egypt) & Singulair 10mg Tabs (Merck)
Comparative randomized, single dose, two-way crossover open-label study to determine the bioequivalence of Montelukast fromAsmakast10 mg tablets (Man.
- Trial name
- NCT02480049
- Testing
- Asmakast, Singulair
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Genuine Research Center, Egypt
Healthy
Bioequivalence Study of Montelukast Sodium Chewable Tablets 4mg and 5mg Under Fed Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01674517
- Testing
- Montelukast sodium chewable tablets 4mg and 5mg
- Where
- India
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Covid19, SARS (Disease)
Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19:
Recently, a new clinical presentation called "long covid" has been reported, for patients with symptoms lasting for more than 4 weeks from the onset of the disease.
- Trial name
- E-SPERANZA (NCT04695704)
- Testing
- Montelukast
- Where
- 8 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Asthma, Exercise-Induced
Montelukast in Exercise-Induced Bronchospasm - 2003 (0476-270)
The purpose of this study is to determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as…
- Trial name
- NCT00092131
- Testing
- Comparator: Montelukast
- Volunteers
- 51 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Effect of Loratadine/Montelukast Combination on Congestion in SAR Patients Exposed to Pollen in an EEU (Study P04822)
This is study of LMC, phenylephrine, and placebo in subjects with SAR. There are three visits: At Visit 1, subjects will be evaluated for participation and, if they qualify, will attend Visit 2 for priming.
- Trial name
- NCT00423995
- Testing
- Loratadine/montelukast combination
- Volunteers
- 379 people
- Sponsor
- Organon and Co
Asthma
MK0476 Study in Adult Patients With Acute Asthma (0476-322)
This study evaluates the efficacy and safety of MK0476 intravenous administration in adult patients with acute asthma.
- Trial name
- NCT00229970
- Testing
- montelukast sodium
- Volunteers
- 225 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
Montelukast in Seasonal Allergic Rhinitis: Fall 2001 Study (0476-240)
This is a study to evaluate the treatment effect of montelukast 10 mg taken in the morning, versus placebo, in patients with seasonal allergic rhinitis. Loratadine is included in the study as an active control.
- Trial name
- NCT00963469
- Testing
- montelukast sodium, Comparator: loratadine
- Volunteers
- 1,079 people
- Sponsor
- Organon and Co