Clinical trials: Mood Change
Childhood Trauma, Major Depressive Disorder
HPA Axis Activity Due To Early Traumatic Stress and Metabolic Symptoms
This study evaluates the association between early trauma, depression and metabolic symptoms.
- Trial name
- Cort-Metab (NCT02398877)
- Testing
- stress
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Unipolar Depression, Anxiety Disorders
Effects of Mindfulness Based Cognitive Therapy on Emotional Processing
Background: In the last 30 years mindfulness-based approaches have been extensively used for a variety of mental disorders, including affective disorders characterized by emotional instability.
- Conditions
- Unipolar Depression, Anxiety Disorders, Adjustment Disorders, Emotional Instability
- Trial name
- MESI (NCT03358056)
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Parc de Salut Mar
Irritable Aggression
Depakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood Swings
Though the Disruptive Disorders of Childhood and Adolescence are a major source of morbidity and fill a large proportion of special education slots, specific pharmacologic treatment is available only for those children with…
- Trial name
- NCT02078596
- Testing
- Divalproex
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute
Depression, Bipolar
Functional and Neurochemical Brain Changes Bipolar Depression
The purpose of the research is to study brain structure, function and chemistry of patients with bipolar disorder who are receiving quetiapine or lithium, in order to better understand who benefits from treatment and why they…
- Trial name
- NCT00608296
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Cincinnati
Anxiety, Depression
Depression and Anxiety Reduction Treatment for Suicide
The purpose of this study is to test the effectiveness and usability of multiple computer-based treatments for mood and anxiety relevant risk factors.
- Conditions
- Anxiety, Depression, Suicide
- Trial name
- DARTS (NCT01941862)
- Testing
- Psychoeducation and Cognitive Bias Modification
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida State University
Bipolar Affective Disorder
Compassion-Focused Therapy for Distressing Mood Swings: A Case Series
The goal of this case series is to investigate whether a brief compassion-focused intervention is a safe, acceptable and feasible therapy for clients with bipolar affective disorder.
- Trial name
- NCT05860101
- Testing
- Compassion-Focused Therapy
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Institute of Psychiatry, London
Bipolar Disorder, Weight Gain
Topiramate vs. Placebo in Preventing Weight Gain in Bipolar Disorder Treated With Olanzapine
The primary objective of this study is to examine the efficacy of topiramate in combination with olanzapine for the prevention of weight gain in youth with bipolar disorder.
- Trial name
- NCT00394095
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Cincinnati
Major Depressive Disorder (MDD)
Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People
Major depressive disorder was shown to be associated with pathological alterations within neurotransmitter systems of the brain.
- Trial name
- NCT06675851
- Testing
- WELLBUTRIN SR (Bupropion HCI) Sustained-Release Tablets, 150 mg; GlaxoSmithKline, Cipralex (escitalopram)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Major Depressive Disorder, Neuroticism
Predictors of Cognitive Outcomes in Geriatric Depression
This study will focus on examining effects of stress on long-term mood and cognitive outcomes of late-life depression. It will also example the neural underpinnings of these changes using structural and functional brain imaging.
- Conditions
- Major Depressive Disorder, Neuroticism, Cognitive Change, Stress
- Trial name
- NBOLD (NCT05273996)
- Testing
- Sertraline, bupropion, desvenlafaxine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- David Steffens