Clinical trials: Mood Disorders
Depressive Disorder
Memory Changes in Patients With Major Depression Disorder Treated With ECT
The basic memory changes (impairment) present in patients with major depression and the influence of the treatment with ECT.
- Trial name
- NCT03915821
- Testing
- ECT
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Bipolar Disorder
DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder
A phase 4 unequal randomization, double blind study to evaluate the dose tolerance and safety of extended release Equetro (carbamazepine) versus placebo followed by an Open label and long term maintenance treatment in children…
- Trial name
- NCT02623504
- Testing
- Carbamazepine
- Where
- 4 sites in United States
- Volunteers
- 17 people
- Sponsor
- Validus Pharmaceuticals
Bipolar I Disorder
A Multicenter, Investigative Study of the Safety and Efficacy of Extended Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode
To assess the safety and efficacy of long-term administration of aripiprazole by performing extended administration of aripiprazole in combination with mood stabilizer (lithium or valproate) in an unblinded manner to those…
- Trial name
- NCT00606320
- Testing
- Aripiprazole
- Where
- 12 sites in China, Japan and 2 more
- Volunteers
- 59 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Depression, Bipolar
A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
This is an 8-week, multicenter, randomized, double blind, placebo controlled study to evaluate the efficacy and safety of aripiprazole as an adjunctive treatment with mood stabilizer for the treatment of patients (outpatients or…
- Trial name
- APOLLO (NCT03423680)
- Testing
- Abilify 2, 5, 10, 15mg (Tablet)
- Where
- South Korea
- Volunteers
- 390 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Bipolar Disorder
Epidemiological Study to Evaluate Adherence to Treatment in Bipolar Disorder: Adherence Study
The purpose of this study is to estimate adherence to treatment in bipolar patients, to characterize patients based on adherence degree and to describe the variables linked to poor adherence to treatment in real-life practice.
- Trial name
- NCT00927420
- Where
- 24 sites in Spain
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Schizophrenia, Diabetes
Medication Reviews in Severe Mental Illness
This study aims to investigate the potential beneficial effects of a medication review by a clinical pharmacologist on patients with coexisting severe mental illness and diabetes.
- Conditions
- Schizophrenia, Diabetes, Metabolic Syndrome, Severe Mental Disorder
- Trial name
- NCT05243160
- Testing
- medication review
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Mood Disorders, Schizophrenia Spectrum and Other Psychotic Disorders
Low Pulse Amplitude Seizure Therapy (LAP-ST Study)
This study assesses the feasibility of a full course of Low Pulse Amplitude-Seizure Therapy (LAP-ST) (primary outcome).
- Trial name
- NCT02928159
- Testing
- Mecta spectrum 5000Q device
- Volunteers
- 22 people
- Sponsor
- Behman Hospital
Anxiety Disorders, Depressive Disorders
Role of the Stress in the Development of the Metabolic Syndrome
The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people of high risk, of 40 or more years and attended in the Primary Care.
- Conditions
- Anxiety Disorders, Depressive Disorders, Metabolic Syndrome, Stress Disorders
- Trial name
- STREX (NCT01538082)
- Where
- Spain
- Volunteers
- 738 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Depressive Disorder, Major
Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder?
Repeated Transcranial Magnetic Stimulation - R.TMS - is currently part of the treatment for depressive illness. This non-invasive technique is designed to stimulate certain areas of the cerebral cortex involved in this pathology.
- Trial name
- DESTIMCARE (NCT03436823)
- Testing
- nurse semi-structured interview, Music & Relaxation with eyes closed
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Premature, Low Birth Weight
Effect of Kangaroo Baby Massage on Mother-infant Interaction at Home
The objective of this randomized clinical trial will determine the effectiveness of nursing intervention (Kangaroo Baby Massage) on the interaction between mothers and premature, low birth weight infants at home The dyad mother…
- Conditions
- Premature, Low Birth Weight, Mother-Infant Interaction, Gain, Weight
- Trial name
- KBM (NCT04908332)
- Testing
- Kangaroo Baby Massage
- Where
- Colombia
- Volunteers
- 68 people
- Sponsor
- Universidad Nacional de Colombia
Depressive Disorder, Malingering
Diagnosis of Depressive Disorder Malinger Using the Niacin Skin Response Test (NSRT)
This study will explore the specific response characteristics of the niacin skin response test in the population with depressive disorder malinger.
- Trial name
- NCT06382532
- Testing
- Niacin skin reaction test
- Where
- China
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Internalizing Mental Health Symptoms, Sleep Problems
Pilot Sleep Extension and Mood
The goal of this interventional study is to learn if a digital sleep extension intervention can improve sleep and mood in young urban adults with mood symptoms.
- Trial name
- NCT06675799
- Testing
- Sleep Extension, Healthy Living Psychoeducation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Illinois at Chicago
Mood Disorder, Bipolar Disorder
Examination of Brain Serotonin Receptors in Patients With Mood Disorders
The purpose of this study is to evaluate the function of certain brain chemicals and receptors in patients with mood disorders. This study will also examine how the stress hormone cortisol affects brain function.
- Conditions
- Mood Disorder, Bipolar Disorder, Depression
- Trial name
- NCT00026832
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder
Cycloserine rTMS Plasticity Augmentation in Depression
Transcranial magnetic stimulation (rTMS) is an investigational and therapeutic modality that impacts the connection strength between neurons by delivering patterned energy.
- Trial name
- NCT03511599
- Testing
- Cycloserine, Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Posttraumatic Stress Disorder, Major Depressive Disorder
rTMS for PTSD Comorbid With Major Depressive Disorder
The purpose of this study is to see how well a treatment called "Repetitive Transcranial Magnetic Stimulation" works for patients who struggle with symptoms of both posttraumatic stress disorder and major depressive disorder.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Transcranial Magnetic Stimulation, Repetitive
- Trial name
- NCT02273063
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Butler Hospital
Minor Depressive Disorder, Major Depressive Disorder
"Mamá, te Entiendo" App-based Intervention for Reducing Depressive Symptoms in Postpartum Women
Title: "Feasibility and acceptability study of "Mamá, te entiendo": an app-based intervention for reducing depressive symptoms in postpartum women" Funding: This work was funded by the Chilean National Agency of Research and…
- Conditions
- Minor Depressive Disorder, Major Depressive Disorder, Post Partum Depression
- Trial name
- NCT05643898
- Testing
- Mamá, te entiendo (Mom, I get you)
- Volunteers
- 66 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Depression, Bipolar, Depression, Unipolar
Pramipexole to Target "Anhedonic Depression"
The heterogeneity of depression suggests that different neurocircuits and pathophysiological mechanisms are involved. Anhedonia - the inability to experience pleasure from, or the lack of motivation to carry out, usually…
- Conditions
- Depression, Bipolar, Depression, Unipolar, Dysthymia, Anhedonia
- Trial name
- PILOT-PRAXOL (NCT04121091)
- Testing
- Pramipexole Pill
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Treatment-resistant Depression
Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) I
Our hypothesis is that targeted propofol infusion in treatment-resistant depressed patients will induce slow wave activity during sedation and augment subsequent sleep slow wave activity.
- Trial name
- NCT04680910
- Testing
- Propofol, Electroencephalography (EEG), Slow-Wave Activity
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Depressive Disorder, Major
Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking
The purpose of this study is to decode different thinking states from the brain activation patterns and identify the neural circuits that disengage from these thinking patterns using functional magnetic resonance imaging (fMRI)…
- Trial name
- RNT-decoding (NCT06254144)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Major Depressive Disorder (MDD)
Context-Guided Personalized iTBS for Depression
The goal of this randomized clinical trial is to learn whether context-guided personalized intermittent theta burst stimulation (iTBS) works better than standard iTBS for adults with major depressive disorder.
- Trial name
- NCT07743398
- Testing
- Context-Guided Personalized Intermittent Theta Burst Stimulation, Standard Left DLPFC Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University