Clinical trials: Mood Lability
Self Harm, Suicide, Attempted
Emotional Dysregulation in Para-suicidal Behavior
This is a naturalistic cohort pre-post study investigating aspects of emotional processing and how possible changes in emotional processing is related to the successful treatment of non-suicidal self-injury and suicidal ideation…
- Conditions
- Self Harm, Suicide, Attempted, Emotional Instability, Borderline Personality Disorder
- Trial name
- NCT03846375
- Testing
- Psychotherapy, Pre-intervention testing
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Alcohol Craving, Mood Changes
A Dose Response Effect of Atomoxetine to the Acute Effects of Alcohol
This two-stage study will examine the effects of a 5 day course of atomoxetine (placebo, 40, 60 or 80 mg/day; Strattera) (a selective NE transporter (NET) inhibitor) on alcohol-elicited craving and sensitivity to alcohol.
- Trial name
- ATX_COMT (NCT01408589)
- Testing
- Atomoxetine, Strattera
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Change in Mood, Change in Personality
The Effect of LentinexHP® on Quality of Life in Stage IV Colorectal Cancer
This is a randomized, double-blind parallel-group, placebo-controlled study. that will last 40 weeks and will focus on Quality of Life.36 Subjects with stage IV metastatic colorectal cancer will be referred for study inclusion.
- Trial name
- NCT05954390
- Testing
- Undenatured beta-glucan solution
- Where
- Bulgaria
- Volunteers
- 36 people
- Sponsor
- GlycaNova AS
Mood Change, Emotion Regulation
Interoception and Emotion Regulation
The goal of this observational study is to examine the role of interoception in emotion regulation of negative mood in healthy individuals. Participants will fulfill several questionnaires and perform the Heartbeat Counting Task.
- Trial name
- INTEROEMOTION3 (NCT05684614)
- Testing
- Negative mood induction procedure, Spontaneous emotion regulation task, Positive mood induction procedure
- Where
- 3 sites in Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Hot Flashes, Night Sweats
Comparison of Hormonal Therapy: Mediating Hot Flashes Tapering Regimens for Mediating Hot Flashes
This study will evaluate whether there is a difference in the proportion of women who report a worsening severity of their hot flashes between three tapering schedules for one accepted HT/ET regimen.
- Trial name
- NCT00547001
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Contraception, Mood Change
Stress Hormones and IUDs
Determine what kind of side effects women experience in the first year after they start using an intrauterine device.
- Trial name
- NCT03499379
- Testing
- Mirena, Paraguard
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Menopause
Estrogen and Serotonin on Changing Brain Chemistry
The aim of this study is to examine the effects of estrogen and serotonin on cognition, emotional processing, and brain activation.
- Trial name
- NCT01208324
- Testing
- estrogen patch, Amino acids
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mood Lability, PTSD
FamilyLive Feasibility and Effectiveness Study
Children who have been exposed to trauma (defined as physical, sexual or emotional abuse, neglect, exposure to life threatening events, domestic and community violence, parental mental health disorders, substance abuse, and/or…
- Conditions
- Mood Lability, PTSD, Anxiety
- Trial name
- NCT01524185
- Testing
- FamilyLive, Standard Mental Health Treatment
- Where
- United States
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Cognitive Change, Creativity
Naturalistic Study of Microdosing With Psilocybin
This study seeks to understand the neural, cognitive and behavioral effects of low doses of psilocybin administered in the form of dried mushroom material (0.5 g of Psilocybe cubensis) consumed in natural settings following a…
- Conditions
- Cognitive Change, Creativity, Mood Change, Sleep
- Trial name
- NATMICRO (NCT05160220)
- Testing
- Psilocybin
- Where
- Argentina
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Mood Change, Depressive Symptoms
Mind-Body Skills Group for Graduate Students
Integrative-Mind-Body Skills Group (I-MBS-G) is an 8-week group that teaches skills to build inner resources for effective mood management.
- Conditions
- Mood Change, Depressive Symptoms, Anxiety Generalized
- Trial name
- NCT05447689
- Testing
- Integrative-Mind-Body Skills Group
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Alzheimer's Disease, Agitation
Citalopram for Agitation in Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of citalopram for agitation in Alzheimer's dementia.
- Trial name
- CitAD (NCT00898807)
- Testing
- citalopram
- Where
- 8 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- JHSPH Center for Clinical Trials
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Insomina, Mood Change
Integrating Smart Wearable Device Into Digital Insomnia Treatment Application: Exploration of Combining Emotional and Lifestyle Records
Emotions, behavior, and cognition are the main factors contributing to insomnia. Insomnia not only affects sleep quality but also harms health, quality of life, and daytime functioning.
- Trial name
- NCT07600840
- Testing
- Personalized Experience Sampling Method, Non-personalized Experience Sampling Method
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Technology
Anesthesia, General, Psychology, Child
Mood Change After General Anesthesia in Children
Most drugs used in general anesthesia work on various receptors in the human brain, causing unconsciousness, loss of memory, and loss of reflection of the autonomic nervous system.
- Conditions
- Anesthesia, General, Psychology, Child, Child Behavior
- Trial name
- NCT03581526
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Daegu Catholic University Medical Center
Emotional Distress, Impulsive Behavior
Neurobehavioral Affective Control Training
The goal of this clinical trial is to test a new cognitive training program to improve emotion regulation in adults. The investigators' primary aim is to determine whether participating in this program addresses two key features…
- Conditions
- Emotional Distress, Impulsive Behavior, Mood Lability, Mood Instability
- Trial name
- N-ACT (NCT06226467)
- Testing
- Neurobehavioral Affective Control Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Berkeley
Cognitive Change, Mood Change
Cognitive Effects of Sage in Healthy Humans
Extracts of sage and polyphenols have separately been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has combined these interventions.
- Trial name
- NCT03695003
- Testing
- Cognivia
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Unipolar Depression, Anxiety Disorders
Effects of Mindfulness Based Cognitive Therapy on Emotional Processing
Background: In the last 30 years mindfulness-based approaches have been extensively used for a variety of mental disorders, including affective disorders characterized by emotional instability.
- Conditions
- Unipolar Depression, Anxiety Disorders, Adjustment Disorders, Emotional Instability
- Trial name
- MESI (NCT03358056)
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Parc de Salut Mar
Breakthrough Bleeding, Breakthrough Spotting
Management of Breakthrough Bleeding During Extended Therapy Use With NuvaRing®
The purpose of this research study is to evaluate the best way to manage breakthrough spotting and bleeding during an extended use regimen of NuvaRing®.
- Trial name
- NCT00475553
- Testing
- remove ring if bleeding or spotting occurs more than 5 days, If bleeding does not remove ring
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Sleep Disorders, Circadian Rhythm
Actigraphic Measurement of a Neurosurgical Procedure
The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.
- Conditions
- Sleep Disorders, Circadian Rhythm, Pain, Rehabilitation
- Trial name
- NCT00945230
- Testing
- Re-section of a large left anterior cranial fossa meningioma
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Child Psychopharmacology Institute
Irritable Aggression
Depakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood Swings
Though the Disruptive Disorders of Childhood and Adolescence are a major source of morbidity and fill a large proportion of special education slots, specific pharmacologic treatment is available only for those children with…
- Trial name
- NCT02078596
- Testing
- Divalproex
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute