Clinical trials: Morbidity
Autoimmune Bullous Dermatosis, Glucocorticoids Toxicity
Investigating the Morbidity of Glucocorticoid Use in Patients With Autoimmune Bullous Diseases (AIBDs)
This project utilised the validated glucocorticoid toxicity index (GTI) tool to assess the morbidity of glucocorticoid-use in patients with autoimmune bullous disease.
- Trial name
- NCT05525065
- Testing
- GlucoCorticoid
- Where
- Australia
- Volunteers
- 138 people
- Sponsor
- Premier Specialists, Australia
Postpartum Depression (PPD), Cardiac Event
Living Healthy for Moms RCT
LHMoms is a novel integrated care intervention that focuses intensively on care continuity and community-to-healthcare linkages for postpartum birthing individuals.
- Trial name
- LHMoms (NCT06666400)
- Testing
- LHMoms Intervention, No intervention
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Columbia University
Hiv
Clinical Outcomes in HIV With Comorbidities
Multi-arm, non-randomized, quality of life
- Trial name
- NCT05824130
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Grace Lui
Colorectal Cancer, Anaesthesia
Cardiopulmonary Exercise Testing and Preoperative Risk Stratification
The investigators would like to evaluate the use of cardiopulmonary exercise tests (CPX) in guiding the care pathway of patients undergoing colorectal operations.
- Conditions
- Colorectal Cancer, Anaesthesia, Critical Illness
- Trial name
- NCT00737828
- Testing
- Perioperative care pathway guided by CPX results
- Where
- 3 sites in United Kingdom
- Volunteers
- 228 people
- Sponsor
- University College London Hospitals
Pharmacological Action, Post Operative Pain
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery
The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion.
- Conditions
- Pharmacological Action, Post Operative Pain, Opioid Use, Obesity, Morbid
- Trial name
- NCT05591105
- Testing
- Control Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Tiva Group
Congenital Heart Defect
The Effects of Inhaled Nitric Oxide After Fontan Operation
Pleural effusions continue to be a post-operative complication seen after Fontan operation. This study will examine the use inhaled nitric oxide (iNO) given for 54 hours after Fontan operation to improve fluid balance.
- Trial name
- NCT00945529
- Testing
- inhaled nitric oxide (iNO)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ellen Spurrier
Malaria, HIV Infections
Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women
This study is an open-label, single site, randomized controlled trial comparing protease inhibitor (PI)-based antiretroviral therapy (ART) to non-PI based ART for HIV-infected pregnant and breastfeeding women of all CD4 cell…
- Trial name
- PROMOTE-PIs (NCT00993031)
- Testing
- Lopinavir/ritonavir, Efavirenz, Zidovudine
- Where
- Uganda
- Volunteers
- 389 people
- Sponsor
- University of California, San Francisco
Thorax Traumas
The Investigation of Predicting Mortality and Morbidity in Patients Admitted to Intensive Care Unit With Thoracic Trauma Using Selected Biomarkers and Parameters
This prospective study aimed to predict morbidity and mortality after thoracic trauma in intensive care unit evaluated clinical and biochemical data of 50 intensive care unit patients.
- Trial name
- NCT06930222
- Testing
- blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Suleyman Demirel University
Uremia, Elderly (Aged >70)
Very Low Protein Diet or Dialysis in Uremic Elderly?
There are no solid data on the real advantage of an early start of dialysis, as suggested by the DOQI guidelines. Uremic patients frequently have a poor nutritional status.
- Conditions
- Uremia, Elderly (Aged >70), Dialysis, Low Protein Diet
- Trial name
- NCT00388648
- Testing
- mixture of amino and keto acids
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Università degli Studi di Brescia
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
The Effect of Prophylactic Hemodialysis on the Morbidity and Mortality of the Patients With Chronic Kidney Disease Stages 3-4 Undergoing Coronary Artery Graft Bypass
Coronary artery disease is a major cause of death in patients with renal dysfunction Among patients who undergo coronary artery bypass grafting ,renal dysfunction is known To be a major predictor of in-hospital and remote…
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Coronary Artery Disease
- Trial name
- NCT01410617
- Testing
- hemodialysis
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Imam Khomeini Hospital
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Chest Wall Tumor, Breast Cancer
Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease
Radiation therapy is an essential treatment for tumors in the chest area, including breast, lung, esophageal, mediastinal cancers, and spine metastases.
- Conditions
- Chest Wall Tumor, Breast Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- NCT07685938
- Testing
- Atorvastatin and Lisinopril
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cerebral Palsy
Diet and Activity in Cerebral Palsy
This study aims to fill a gap in the literature, identify relevant clinical measures, and provide insight into the independent modifiable risk factors of obesity in the CP population with the long-term goal of improving…
- Trial name
- NCT02175108
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Shirley Ryan AbilityLab
Postpartum Hemorrhage
Misoprostol for the Treatment of Postpartum Hemorrhage
The purpose of this study is to test whether misoprostol is as effective as oxytocin for treating primary postpartum hemorrhage (PPH) with uterine atony as the suspected cause in two circumstances: 1) where women have received…
- Trial name
- NCT00116350
- Testing
- Misoprostol, Oxytocin
- Where
- 6 sites in Burkina Faso, Ecuador and 3 more
- Volunteers
- 1,786 people
- Sponsor
- Gynuity Health Projects
Stroke, Ischemic, Cardiovascular Risk Factor
Development of a Prognostic Tool for the Stratification of Cardiovascular Risk in Patients With Ischemic Stroke
The availability of several high-cost strategies for the prevention of cardiovascular morbidity and mortality in patients with established cardiovascular disease highlights the necessity of reliable risk stratification of these…
- Conditions
- Stroke, Ischemic, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Morbidity
- Trial name
- NCT04189497
- Where
- Greece
- Volunteers
- 3,500 people
- Sponsor
- University of Thessaly
Malnutrition
Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery
This study is to compare the sustained post-discharge nutritional support to reach individual energy and protein goals to usual care home nutrition in medical patients at nutritional risk.
- Trial name
- EFFORT II (NCT04926597)
- Testing
- nutritional supplement, individualized nutritional guidelines, general nutritional information
- Where
- 18 sites in Spain, Switzerland
- Volunteers
- 1,200 people
- Sponsor
- Philipp Schuetz
Puerperal Sepsis
Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women
Postpartum infections are among the leading causes of maternal mortality world-wide, particularly in under-resourced countries. Available data suggests that HIV infected women are at greater risk of postpartum complications than…
- Trial name
- NCT00343317
- Where
- South Africa
- Volunteers
- 1,372 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Placenta Accreta
Comparison Between Hysterectomy and Conservative Management in Treatment of Placenta Accreta Regarding Maternal Complication
AIM OF THE WORK The aim of the study is to compare the maternal morbidity and mortality between obstetric hysterectomy and conservative surgery for pregnant ladies > 28 weeks with placenta accreta during caesarean section at Ain…
- Trial name
- NCT03327818
- Testing
- hysterectomy, uterine conservative study
- Volunteers
- 491 people
- Sponsor
- Ain Shams Maternity Hospital
Malaria
School Based Malaria Control in Ugandan Schoolchildren
The investigators hypothesize that schoolchildren treated with IPT using DP over one year of follow-up will have a different risk of clinical malaria compared to those treated with placebo.
- Trial name
- SBMC (NCT01231880)
- Testing
- Four monthly IPT with dihydroartemisinin Piperaquine (DP), Monthly IPT using DP
- Where
- Uganda
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Makerere University
Essential Hypertension
Observational Study of Efficacy and Safety of Nebivolol in Korean Patients With Essential Hypertension
The purpose of this study is: To evaluate the effects of NEBILET®(Nebivolol), used as monotherapy or in combination with other antihypertensive agents, in the control of BP and in the metabolic profile of patients with essential…
- Trial name
- BENEFIT (NCT03847350)
- Where
- South Korea
- Volunteers
- 3,250 people
- Sponsor
- A.Menarini Asia-Pacific Holdings Pte Ltd