Clinical trials: Morbidly Obese Patients
Obese Adolescents, Bariatric Surgery
Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia
study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia and provide improvement in recovery
- Trial name
- modafinil (NCT07128719)
- Testing
- Modafinil
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Morbid Obesity
Two Different Regimens of Bemiparin as a Thromboprophylaxis in Morbidly Obese Surgical Patients
Morbid obesity, is known to be associated with a high risk of VTE and, unfortunately, fixed doses of anticoagulant regimens may not provide optimal VTE prophylaxis in these patients especially after surgery.
- Trial name
- NCT05569681
- Testing
- Bemiparin 3500, Bemiparin 5000 IU
- Where
- Iraq
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
ESPB With Dexmetomidine May Provide Analgesia
Analgesic Efficacy of Adding Different Doses of Dexmedetomidine as Adjuvants With Bupivacaine vs.Bupivacaine Only in Ultrasound-guided Erector Spinae Plane Block in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery. A Randomized Controlled Double Blinded Study.
Analgesic Efficacy of adding different doses of dexmedetomidine as adjuvants with bupivacaine vs. bupivacaine only in ultrasound-guided erector spinae plane block in morbidly obese patients undergoing Laparoscopic Bariatric…
- Trial name
- NCT07380503
- Testing
- Analgesic Efficacy of adding different doses of dexmedetomidine
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Morbid, Liver Fibrosis
Performances Evaluation of New FibroScan Probes Dedicated to Morbidly Obese Patients
Non-Alcoholic Fatty Liver is a common clinical and histological condition associated with metabolic syndrome in patients with and without excess body weight.
- Trial name
- NCT03872024
- Testing
- For the first 60 patients: 3 XXL probe prototypes of the FibroScan 630 Research Model, From patient 61 to patient 120: 1 XXL probe prototype of the FibroScan 630 Research Model
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Echosens
Pulmonary Atelectasis, Respiratory Tract Diseases
Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
The aim of this study was to investigate the effects of using positive pressure in the preoperative, intraoperative and postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01786681
- Testing
- Positive pressure
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Surgical Conditions
Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients
This is a randomized control trial (RCT) that studies the surgical conditions during moderate and deep neuromuscular blockade in 100 morbidly obese patients receiving elective laparoscopic surgery for bariatric surgery.
- Trial name
- BLISS3 (NCT02553629)
- Testing
- Rocuronium
- Where
- 2 sites in Netherlands
- Volunteers
- 109 people
- Sponsor
- Leiden University Medical Center
Morbid Obesity
McGrath Videolaryngoscopy and Direct Laryngoscopy in Morbidly Obese Patients
Our goal is to compare conventional direct laryngoscopy using a Macintosh blade with the McGrath videolaryngoscope for endotracheal intubation in very morbidly obese patients undergoing non-cardiac surgery.
- Trial name
- NCT03467048
- Testing
- McGrath videolaryngoscopy, Direct laryngoscopy
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- The Cleveland Clinic
Intratracheal Inbubation
Airway Scope vs GlideScope for Intubation in Obese Patients
This study compares the time required to complete intubation in obese patients (Body Mass Index 40 or greater) when using either the GlideScope or Airway Scope video laryngoscope device to help place the endotracheal tube.
- Trial name
- NCT07453563
- Testing
- Intubation with GlideScope, Intubation with Airway Scope
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of New Mexico
Morbid Obesity, Thromboembolism
Prophylaxis of Venous Thromboembolism After Bariatric Surgery
This study is a prospective evaluation of the relationship between lean body weight and anti-Xa activity and 5700 International Units (IU) nadroparin 4 hours after subcutaneous administration in morbidly obese patients after…
- Conditions
- Morbid Obesity, Thromboembolism, Bypass Complications
- Trial name
- NCT02295150
- Testing
- Nadroparin
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Obesity, Vitamin Deficiency
Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study)
This study is a double blind randomized controlled trial.
- Trial name
- NCT01609387
- Testing
- Fit For me, Davitamon
- Where
- Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Pneumonia
Pharmacokinetic and Pharmacodynamic Evaluation of Linezolid Administered Intravenously in MRSA-positive, Morbidly Obese Patients With Pneumonia
The objectives of the study are: (i) to evaluate the proportion of patients who attain a T>MIC (Minimum Inhibitory Concentration) of 100% and the time frame in which they do so.
- Trial name
- UGENT_LIMOP (NCT01805284)
- Testing
- Linezolid
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Ghent
Morbid Obesity, Acanthosis Nigricans
The Effect of Laparoscopic Sleeve Gastrectomy on Insulin Secretion Pattern in Morbidly Obese Patients With Acanthosis Nigricans
Acanthosis nigricans (AN) is increasing in its prevalence and is the most prevalent cutaneous manifestation in individuals with obesity.
- Conditions
- Morbid Obesity, Acanthosis Nigricans, Insulin Resistance, Insulin Sensitivity
- Trial name
- NCT05529563
- Testing
- LSG
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Shen Qu
Morbid Obesity
Effect of Positive End Expiratory Pressure at the Time of Induction in Morbidly Obese Patients
Background: Positive end expiratory pressure (PEEP) at the time of induction increases oxygenation by preventing lung atelectasis. However, PEEP may not prove beneficial in all cases.
- Trial name
- NCT03024658
- Testing
- positive end expiratory pressure (PEEP)
- Volunteers
- 70 people
- Sponsor
- Sri Aurobindo Institute of Medical Sciences
Appetite Reduction, Weight Loss
Percutaneous Electroneurostimulation of Dermatome T6 for Appetite Reduction and Weight Loss in Morbidly Obese Patients
Based on the creation of a somato-autonomic reflex, the stimulation of sensory nerve terminals located in dermatome T6 may cause a reflex, whose efferent pathways end in vagal nerve branches stimulating the gastric wall…
- Trial name
- NCT01792947
- Testing
- Percutaneous electroneurostimulation of dermatome T6, Diet 1200 Kcal
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Elche
Acetaminophen Toxicity, Obesity, Morbid
Pharmacokinetics and Pharmacodynamics of Intravenous Paracetamol in Morbidly Obese and Non- Obese Patients.
Obese patients may need higher doses of acetaminophen (APAP) for adequate analgesia, due to increased total clearance and distribution volume. APAP-induced hepatotoxicity is mainly caused through CYP2E1 pathway.
- Trial name
- NCT06549062
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- University Hospital, Ghent
Surgical Wound Infection
Supplemental Postoperative Oxygen and Wound Infection in Morbidly Obese Patients
The investigators propose to test the hypothesis that the incidence of major complications related to infection or inadequate healing is reduced in morbidly obese patients given 80% inspired oxygen during, and for 12-18 hours…
- Trial name
- NCT00315822
- Testing
- 80% oxygen, 30% oxygen
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- The Cleveland Clinic
Morbid Obesity
Cefazolin Subcutaneous Microdialysis in Morbidly Obese Patients
The investigators hypothesize that cefazolin perfusion to subcutaneous adipose tissue is reduced in morbidly obese patients. The primary objective of this exploratory pilot study is therefore to investigate target site…
- Trial name
- MICK (NCT01309152)
- Where
- 3 sites in Netherlands
- Volunteers
- 16 people
- Sponsor
- St. Antonius Hospital