Clinical trials: Morbidly Obese Patients
Diastolic Dysfunction, Morbid Obesity
Diastolic Dysfunction in Morbidly Obese Patients Undergo Bariatric Surgery
Morbidly obese patients are at risk for diastolic cardiac dysfunction, which can lead to adverse event, such as, diastolic heart failure postoperatively.
- Trial name
- NCT04128735
- Where
- Thailand
- Volunteers
- 116 people
- Sponsor
- Mahidol University
Bariatric Surgery Candidate, Dysbiosis
The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric Surgery
This study explores the effects of probiotic administration on the outcomes of surgical treatment, and also on the state of the intestinal microbiota and the intestinal barrier.
- Trial name
- NCT05407090
- Testing
- probiotic supplementation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Obesity, Type-2 Diabetes Mellitus
Loop Duodenal Switch Surgery in Morbidly Obese Patients
The loop duodenal switch (L-DS) is a single-anastomosis biliopancreatic diversion with duodenal switch (BPD-DS) procedure. The original BPD-DS has two-anastomosis and is an accepted and approved bariatric procedure by the…
- Trial name
- NCT02671331
- Testing
- Loop duodenal switch
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Medical College of Wisconsin
Morbid Obesity
Boussignac Valve and Fibroptic Intubation in Morbidly Obese Patients, Can it be a Solution?
In this study, fiberoptic intubation through Boussignac valve, while ventilation of morbidly obese patients is maintained through the ventilator, will be studied.
- Trial name
- Obese-FOB (NCT03046797)
- Testing
- Fibroptic intubation through Boussignac valve opening, Classic Fibroptic intubation
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Obesity, Morbidly Obese
Novel SaCoVLM™ Video Laryngeal Mask Airway as an Intubation Conduit in Morbidly Obese Bariatric Surgery
Background: The SaCoVLM™ video laryngeal mask is a novel video-assisted device that integrates the functions of both a dual-channel laryngeal mask airway (LMA) and an intubating laryngeal mask airway (ILMA).
- Trial name
- NCT07573813
- Testing
- SaCoVLM™ in Difficult Airways
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Yongtao Sun
Morbid Obesity
Effect of Oxalidine Combined with Reduced-opioid Anesthesia on Multimodal Analgesia in Morbidly Obese Patients Undergoing Bariatric Surgery
The goal of this study is to elucidate the efficacy and safety of oxelidine combined with oligopiate anesthesia for multi-modal analgesia in weight-loss surgery in morbidly obese patients, and to discover a new strategy for…
- Trial name
- NCT06712199
- Testing
- oxalidine
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Yongtao Sun
Morbid Obesity, Hypertension
Prevention of Coronary Heart Disease in Morbidly Obese Patients
The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied.
- Conditions
- Morbid Obesity, Hypertension, Type 2 DM, Obstructive Sleep Apnea
- Trial name
- SphCor (NCT00626964)
- Testing
- Bariatric Surgery, Conservative Treatment:
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- The Hospital of Vestfold
Intubation, Endotracheal, Anesthesia, General
Tracheal Intubation of Morbidly Obese Patients. GlideScope Versus Direct Laryngoscopy
The purpose of this study is to examine whether orotracheal intubation in morbidly obese patients is faster, gentler and safer using the GlideScope videolaryngoscope than with the Macintosh direct laryngoscope.
- Conditions
- Intubation, Endotracheal, Anesthesia, General, Obesity
- Trial name
- NCT00917033
- Testing
- GlideScope, Macintosh direct laryngoscope
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Oxygen Deficiency, Apnea
Oxygen Reserve Index Predicting Hypoxemia
After obtaining the approval of the hospital ethics committee, this prospective, observational study included written informed consent from 51 participants with 19<BMI<25 m/kg2 and 51 participants with BMI>40 m/kg2 undergoing an…
- Trial name
- NCT05480748
- Testing
- monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Apneic Oxygenation
A "Less-rapid" Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the "Duration of Apnea Without Desaturation" in Paralyzed Non-obese and Morbidly Obese Patients?
The study will test the efficacy of the Pentax AWSTM video laryngoscope (VLS) equipped with a P Blade (Figure 1) as the means to provide Apneic Oxygenation (AO) and prolong Duration of Apnea Without Desaturation (DAWD) in…
- Trial name
- NCT02943629
- Testing
- Apneic oxygenation: Eight minute, Without apneic oxygenation, Apneic oxygenation: five minutes
- Sponsor
- Vanderbilt University
Morbid Obesity
Clinical and Economic Outcomes in Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass Surgery
Study objectives: 1. generate local clinical, health-related quality-of-life and health economic data to evaluate the benefits of two types of minimally invasive weight-loss surgery 2.
- Trial name
- OPTIMIZE (NCT01754194)
- Testing
- Gastric Sleeve Resection, Roux-en-Y Gastric Bypass
- Where
- 18 sites in Germany
- Volunteers
- 293 people
- Sponsor
- Medtronic - MITG
Bariatric Surgery, Obesity, Morbid
Lung Recruitment Manoeuvre in Morbidly Obese Patients Underdoing Laparoscopic Bariatric Surgery
Lung ultrasonography is an easy-to-use, portable, non-invasive, visual, and non-radiative technique that has been widely used in clinical monitoring and diagnosis.
- Trial name
- NCT06000969
- Testing
- Lung Recruitment Conventional, Lung Recruitment Ultrasound
- Where
- 2 sites in Egypt
- Volunteers
- 78 people
- Sponsor
- Tanta University
Morbid Obesity
A Study of Clinical Outcomes of the REALIZE Adjustable Gastric Band-C
The purpose of this study is to evaluate the results patients are obtaining with the Realize™ Adjustable Gastric Band-C during the first 24 months after surgery.
- Trial name
- NCT00999661
- Where
- 7 sites in United States
- Volunteers
- 231 people
- Sponsor
- Ethicon Endo-Surgery
General Anesthesia of Morbid Obese Patients
Ultrasound in Airway Assessment of Morbidly Obese Patients
the study aims to evaluate the role of airway ultrasound as a new evolving modality in assessment and management of airway in surgical patients
- Trial name
- AiUs (NCT02766504)
- Testing
- airway ultrasound
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Apneic Oxygenation, High-flow Nasal Cannulae
High-flow Nasal Oxygenation in Obese Patients During Apnea
Before going off to sleep patients are given oxygen to saturate blood with oxygen to extend time before a decrease in the level of oxygen in the blood occurs.
- Conditions
- Apneic Oxygenation, High-flow Nasal Cannulae, Bariatric Surgery, Anesthesia Induction
- Trial name
- NCT03195504
- Testing
- HFNC, CON (control)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Pain, Postoperative
Comparison of QLB Block and TAP Block in Morbid Obese Patients
Quadratus lumborum block (QLB) and Transversus abdominis plane (TAP) blocks are regional anesthesia techniques that are frequently used to reduce postoperative pain and are an important part of the current analgesic regimen for…
- Trial name
- NCT05820620
- Testing
- TAP block, QLB block, Control Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Biruni University
Obesity, Morbid
Tracheal Intubation in Morbidly Obese (BMI>35) and in Lean (BMI<30) Patients Using McGrath MAC X-Blade
80 lean (BMI<35) and morbidly obese (BMI>35) patients undergoing elective surgery were enrolled in this prospective ransomİzed study were intubated using McGrath MAC X-Blade.
- Trial name
- NCT03759990
- Testing
- lean, obese
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kocaeli University
Morbid Obesity, Type 2 Diabetes Mellitus
Caloric Restriction and Insulin Secretion
Caloric restriction in obese diabetic patients quickly improves glucose control, independently from weight loss. However, the early effects of a very-low calorie diet (VLCD) on insulin sensitivity and insulin secretion in…
- Trial name
- NCT01447524
- Testing
- Very Low Calorie Diet
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Rome Tor Vergata
Hypoxemia, Esophageal Cancer
Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients
Hypoxaemia during sedated gastrointestinal endoscopy exceeds 40 % in morbidly obese (BMI ≥ 35 kg m-²) patients. High-flow nasal cannula alone often fails because of persistent airway collapse.
- Conditions
- Hypoxemia, Esophageal Cancer, Morbidly Obese Patients, Gastric Cancer
- Trial name
- NCT07175155
- Testing
- COMBO Endoscopy Oropharyngeal Airway with High-Flow Nasal Cannula Oxygenation, High-Flow Nasal Cannula Oxygenation
- Where
- 5 sites in China
- Volunteers
- 410 people
- Sponsor
- Zhejiang University
Diabetes
Surgical Treatment of Type 2 Diabetes in Non-Morbidly Obese Patients
The aim of this study is to assess the short term success and feasibility of ileal transposition with sleeve gastrectomy in non-morbidly obese patients with poorly controlled Type 2 Diabetes Mellitus
- Trial name
- NCT00596973
- Testing
- Surgical Treatment
- Where
- United States
- Sponsor
- Medtronic - MITG