Clinical trials: Mortality, open to volunteers
Moderate Aortic Valve Stenosis, Moderate Aortic Valve Regurgitation
Prospective Observational Cohort Study of Moderate Aortic Valve Disease
The objective of this research is to evaluate and predict the progression of moderate aortic stenosis and regurgitation from clinical characterization, biological, echocardiographic, and computed tomography (CT) et. al.
- Conditions
- Moderate Aortic Valve Stenosis, Moderate Aortic Valve Regurgitation, Aortic Valve Disease
- Trial name
- NCT06595992
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Blood Pressure
Association of Inpatient Blood Pressure Levels With In-hospital Adverse Events(APPLE Study)
The purpose of the study is to investigate the association between inpatient blood pressure levels and in-hosopital adverse outcomes.
- Trial name
- NCT04226612
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Surgery, Failure to Rescue
'5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation
'Failure to rescue' describes the preventable death of a patient following the absence of timely identification and treatment of a complication after surgery.
- Trial name
- NCT06997328
- Testing
- Implementation of the '5 Rs to Rescue'
- Where
- South Africa
- Volunteers
- 6,000 people
- Sponsor
- University of Cape Town
Analysis of Pediatric Trauma
Analysis of Pediatric Trauma Registry Data:Patterns,Outcomes,and Predictors of Injury Severity.
Type of the study: A prospective analytical observational study using pediatric trauma registry data. Study period: The study will last for six months.
- Trial name
- NCT07371936
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Liver Transplant Failure, Prognostic Biomarkers
Serum GLYcomics to Predict Graft Loss and Mortality After Liver Transplantation
The first 12 months after liver transplantation (LT) are decisive in posttransplant outcome, as almost half of deaths and two thirds of graft loss requiring retransplant occur in the first year after LT.
- Trial name
- GLYGALT (NCT05866796)
- Testing
- GlycoTransplantTest
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- University Hospital, Ghent
Critical Illness, Malnutrition
Comparing High-protein Vs. Standard Protein Nutritional Support in Critically Ill Patients At Risk for Refeeding Syndrome
The goal of this clinical trial is to determine the optimal protein administration strategy for enhancing both nutritional and clinical outcomes, as well as reducing complications and mortality in ICU patients at risk for…
- Conditions
- Critical Illness, Malnutrition, Refeeding Syndrome, At Risk for Refeeding Syndrome
- Trial name
- NCT06825377
- Testing
- Whey protein
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Shahid Beheshti University
Traumatic Injuries, Prehospital Emergency Care
Study of Pre Hospital Management of Polytrauma Patients by Medical Teams From a Department in the Parisian Region
To study the impact of prehospital management duration by SMUR teams in the Essonne department (91) on early patient mortality (within 24 hours) and to analyze the procedures performed on scene.
- Conditions
- Traumatic Injuries, Prehospital Emergency Care, Early Mortality
- Trial name
- DELTA-91 (NCT07414186)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Sud Francilien
Traumatic Brain Injury
Role of Electrocardiogram Abnormalities in Prediction of Mortality in Patients With Isolated Traumatic Brain Injury
Most common causes of ECG changes, from surgical view, are extradural haemorrhage , intracerebral haemorrhage, intraventricular haemorrhage and subarachnoid haemorrhage.
- Trial name
- NCT06701279
- Volunteers
- 54 people
- Sponsor
- Assiut University
The Number of Ventilator-free Days in the 28 Days Following LT
Veno-arterial ExtraCorporeal Membrane Oxygenation to Reduce Morbidity and Mortality Following Lung TransPlant
In patients undergoing lung transplantation (LT), the investigators hypothesize that a "systematic" intraoperative ECMO strategy would reduce the need for invasive mechanical ventilation in the first 28 days without increasing…
- Trial name
- ECMOToP (NCT05664204)
- Testing
- Veno-arterial extracorporeal membrane oxygenation
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD, Interstitial Pneumonia
Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study
This study analyzes patients who underwent lung transplantation at the First Affiliated Hospital of Zhejiang University from 2017 to 2024, focusing on anesthesia's impact on post-op results.
- Conditions
- COPD, Interstitial Pneumonia, Bronchiectasis, Respiratory Failure
- Trial name
- NCT06922916
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Zhejiang University
Subarachnoid Hemorrhage of Aneurysmal Cause
Observational Study on Mortality and Outcome of Patients Hospitalized for Subarachnoid Hemorrhage of Aneurysmal Origin in Martinique Between 2013 and 2021
The aim of our study is to analyze mortality and sequelae of subarachnoid hemorrhage of aneurysmal origin in hospitalized patients in Martinique. Predictive factors of poor prognosis will also be analyzed.
- Trial name
- HSA Rankin (NCT06525012)
- Testing
- Usual patient care for patients hospitalized for subarachnoid hemorrhage of aneurysmal origin
- Where
- Martinique
- Volunteers
- 122 people
- Sponsor
- University Hospital Center of Martinique
Congenital Heart Disease, Heart Failure
The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R)
Advances in surgical and medical care have led to improved outcomes in patients with congenital heart disease (CHD). As a consequence, the majority of patients nowadays survives to adulthood (adults with CHD, that is, adult CHD…
- Conditions
- Congenital Heart Disease, Heart Failure, Transplant; Complication, Failure, Arrythmia
- Trial name
- ARTORIA-R (NCT04848844)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf