Clinical trials: Mortality Rate
Cholecystitis
Harmonic in Laparoscopic Cholecystectomy for Acute Cholecystitis
In the developmental stage of laparoscopic cholecystectomy it was considered 'unsafe' or 'technically difficult' to perform laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- HAC (NCT00746850)
- Testing
- early LC within 72 hours after the diagnosis with H (Harmonic), early LC within 72 hours after the diagnosis with MD (Monopolar Diathermy)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Bologna
Acute Decompensated Heart Failure
Short-term Mortality Prediction by the SOFA Score in Acute Decompensated Heart Failure
Data on the use of sequential organ failure assessment (SOFA) in patients with cardiovascular disease are increasing. Several studies demonstrated that the SOFA score can identify short-term mortality in patients with acute…
- Trial name
- NCT06354426
- Where
- Vietnam
- Volunteers
- 216 people
- Sponsor
- Hanoi Heart Hospital
Heart Failure
The Darlington Retrospective Outpatient Study
Having heart failure means the heart is unable to pump blood around the body effectively. This reduces life expectancy and hinders normal daily activities.
- Trial name
- DROPSY (NCT01013883)
- Where
- United Kingdom
- Volunteers
- 509 people
- Sponsor
- County Durham and Darlington NHS Foundation Trust
Leukemia, Myeloid, Acute
Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AML
This is a pilot efficacy assessment clinical trial of vosaroxin and cytarabine for the treatment of adults 60 years of age or older with previously untreated acute myeloid leukemia.
- Trial name
- NCT02485353
- Testing
- Vosaroxin and Cytarabine
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Hamid Sayar
COVID, Drug Effect
Assessment of Mortality Rates in COVID-19 Infected Populations Treated With Repurposed Medications
This retrospective cohort study will include eligible patients that received a positive COVID-19 test and filled a new prescription for one of the repurposed medications (including hydroxychloroquine, chloroquine, with or without…
- Conditions
- COVID, Drug Effect, Drug Interaction, Risk Reduction
- Trial name
- NCT04432350
- Where
- United States
- Sponsor
- Tabula Rasa HealthCare
Renal Transplant Recipients
Effects of Whole-body Vibration Training on the Heart Rate Variability Cardiac in Kidney Transplantation
Introduction: Renal transplantation represents the therapeutic mode with more durable treatment, greater cost-effectiveness, survival benefits and quality of life of the patients, however, with high cardiovascular mortality.
- Trial name
- NCT03110406
- Testing
- whole-body vibration training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Diabetes Mellitus, Type 2
Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients
The study aims to evaluate the effects of Insulin Degludec/Liraglutide on glycemic variability assessed by continuous glycemic monitoring with the function time in range, serum markers of inflammation, markers of endothelial…
- Trial name
- NCT05360537
- Testing
- Insulin Degludec / Liraglutide Injectable Product, Insulin Glargine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Recurrence, Survival Rate
Impact of Perioperative Hyperoxia on Cancer Recurrence and Mortality After Elective Colorectal Cancer Surgery
The goal of this observational study is to evaluate whether perioperative hyperoxia (FiO₂ > 0.8), compared to conventional oxygen therapy (FiO₂ < 0.4), is associated with increased cancer recurrence and mortality in patients…
- Conditions
- Recurrence, Survival Rate, Mortality, Colorectal Surgery
- Trial name
- OncO2 (NCT06989346)
- Where
- Spain
- Volunteers
- 403 people
- Sponsor
- Parc de Salut Mar
Pneumonia, Neurological Dysphagia
Drug to Prevent Pneumonia in the Tube Fed
Background: Older people with neurological dysphagia are at risk of recurrent aspiration pneumonia. Angiotensin converting enzyme inhibitor (ACEI) has been shown to improve swallowing and cough reflexes which may protect…
- Trial name
- NCT02358642
- Testing
- Angiotensin converting enzyme inhibitor (Lisinopril)
- Where
- Hong Kong
- Volunteers
- 93 people
- Sponsor
- Chinese University of Hong Kong
Type 2 Diabetes Mellitus
The Sapienza University Mortality and Morbidity Events Rate (SUMMER) Study in Diabetes
This observational study is aimed at identifying new molecular promoters of mortality (and morbidity) in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- SUMMER (NCT02311244)
- Where
- Italy
- Volunteers
- 5,139 people
- Sponsor
- University of Roma La Sapienza
Chromium Deficiency, Diabetes Mellitus
Examination of the Effects of Chromium Levels on Glucose Metabolism, Lipid Metabolism, Morbidity and Mortality Rates in Patients Followed in Intensive Care Unit
The goal of this observational study is to determine the effects of chromium serum levels on glucose metabolism, lipid metabolism, morbidity and mortality rates in critically ill intensive care patients.
- Conditions
- Chromium Deficiency, Diabetes Mellitus, Hyperlipidemias, Hypercholesterolemia
- Trial name
- NCT06334042
- Testing
- Serum Chromium Level
- Where
- Turkey (Türkiye)
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Oguzhan Kahveci
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Sudden Death
Death Rate in Anesthesia, a Study in a Tertiary Hospital
Death rate in anesthesia is one of the most valuable methods to assess the safety of anesthesia practice among different types of patients.
- Trial name
- NCT02732067
- Testing
- anesthesia related deaths
- Where
- Jordan
- Volunteers
- 30 people
- Sponsor
- University of Jordan
Covid19, Diabetes Mellitus
The Effect of Diabetes Mellitus on the Prognosis of Patients With COVID-19
All hospitalised patients with COVID-19 who have positive RT-PCR for SARS-COV-2 will be included in the study. The patients will be divided into two groups, as diabetics and non-diabetics.
- Trial name
- COVID-19-DM2 (NCT04591704)
- Testing
- hospitalisation, necessity of ICU, mortality rate, lung involvement
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Uşak University
Abdominal Injury, Thoracic Injury
Outcome of Patients With Thoraco-abdominal Injury and Stress-induced Hyperglycemia or Diabetic Hyperglycemia
This study aimed to measure the effects of SIH and DH on the mortality outcomes of the adult patients with moderate to severe thoracoabdominal injury
- Conditions
- Abdominal Injury, Thoracic Injury, Hyperglycemia, Hyperglycemia Stress
- Trial name
- NCT04058015
- Testing
- Stress-induced hyperglycemia, Diabetic hyperglycemia, Diabetic normoglycemia
- Where
- Taiwan
- Volunteers
- 802 people
- Sponsor
- Chang Gung Memorial Hospital
Mortality Rate, Hemorrhagic Shock
Low Dose of Norepinephrine Within 24-Hour Mortality in Traumatic Patient With Hemorrhagic Shock
The aim of the work is to evaluate role of low dose of nor epinephrine administration in the early 24-hour period among traumatic patients and hemorrhagic shock. The primary outcome: evaluate mortality at first 24 hour.
- Trial name
- NCT07053163
- Testing
- Crystalloid and blood as resuscitation, crystalloid, blood and low dose of norepinephrine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Endometrial Carcinoma
Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates
This phase I trial investigates the development of a new early detection test to reduce racial disparities in endometrial cancer death rates.
- Trial name
- NCT04474184
- Testing
- Biospecimen Collection, Focus Group, Survey Administration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sudden Death
Death Rate in Anesthesia: A Study in a Tertiary Hospital
Death rate in anesthesia is one of the most valuable methods to assess the safety of anesthesia practice among different types of patients.
- Trial name
- NCT02685540
- Where
- Jordan
- Volunteers
- 792 people
- Sponsor
- University of Jordan
Community Based Study, Cardiovascular Disease
Heart Rate, Baroreflex Sensitivity and Cardiovascular Morbidity and Mortality in the Population
The aim of the present Paris Prospective Study III (PPS3) is (1) to assess the determinants of the regulation of heart rate and blood pressure variations and carotid properties (under different physiologic stimulations) and (2)…
- Conditions
- Community Based Study, Cardiovascular Disease, Sudden Death, Blood Pressure
- Trial name
- PPSIII (NCT00741728)
- Testing
- Spider flash ECG, high-precision carotid echo-tracking, step test
- Where
- France
- Volunteers
- 10,157 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Death
Evolution of the Rate and Causes of Death in Geriatric SSR
In view of the ageing population and the increasing fragility of geriatric patients, it seems interesting to carry out a retrospective epidemiological observational study, on the evolution of the mortality rate and the causes of…
- Trial name
- NCT03985332
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France