Clinical trials: Mother
Phenylketonuria
Low Phenylalanine Diet for Mothers With Phenylketonuria (PKU)
Phenylketonuria (PKU) is a rare genetic condition. If not treated, PKU can cause severe mental retardation. Women with PKU are advised to eat a special diet when pregnant to prevent mental retardation in their children.
- Trial name
- NCT00065299
- Testing
- Restricted phenylalanine diet
- Where
- 3 sites in United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Low Birth Weight
Kangaroo Mother Care Implementation Research for Accelerating Scale-up
The implementation research project aims to develop and evaluate models for scaling up KMC in health facilities across India and Ethiopia and thereby develop effective approaches to achieve high population coverage
- Trial name
- NCT03506698
- Testing
- Kangaroo Mother Care (KMC)
- Where
- 3 sites in Ethiopia
- Volunteers
- 3,804 people
- Sponsor
- Rajiv Bahl
COVID-19
COVID Booster in Pregnancy and Lactation
This is a prospective longitudinal cohort study to evaluate the impact of COVID-19 vaccination and booster on maternal and infant immunity against COVID-19 variants over time.
- Trial name
- NCT05543993
- Testing
- Bivalent COVID-19 Booster
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Maternal Behavior
Midwife-led Continuity and Satisfaction With Care - an Observational Case-Control Study in Palestine
This study investigate if a midwife-led continuity model of care in Palestine, had impact on rural women's satisfaction with care through the continuum of antenatal, intrapartum and postnatal period.
- Trial name
- NCT03863600
- Testing
- Midwife-led continuity of care
- Where
- Palestinian Territories
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Gestational Diabetes Mellitus (GDM), Pregnancy
Gestational Diabetes and Health Outcomes in Mothers and Babies
Gestational diabetes mellitus (GDM) is a common pregnancy complication characterized by impaired glucose metabolism and increased insulin resistance.
- Trial name
- GRAZ-GDM (NCT07459907)
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Graz
Parenting Capacities of Substance Abusing Mothers
Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
A formal randomized efficacy trial testing the Mothers and Toddlers' program, an attachment-based parenting intervention for mothers enrolled in addiction treatment and caring for young children.
- Trial name
- NCT01240993
- Testing
- Mothers and Toddlers Program, Parent Education
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Investigation or Care in A Nonpregnant Woman, Mother (Person)
Pelvic Floor Muscle Function in Nulliparous and Primiparous.
This study aimed to compare the pelvic floor muscle (PFM) strength in nulliparous and primiparous women. Subjective evaluation of PFM strength was performed vaginal digital palpation (TDP).
- Trial name
- NCT01315769
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Systemic Lupus Erythematosus, Contraception
The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB
While the HOP-STEP (Healthy Outcomes in Pregnancy with SLE Through Education of Providers) program has been demonstrated to be effective in improving provider confidence, increasing contraception documentation, and facilitating…
- Trial name
- HOP-STEPsIRB (NCT05818254)
- Testing
- HOP-STEP (Healthy Outcomes in Pregnancy with SLE Through Education of Providers) Intervention, Routine Care
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Preeclampsia, Fetal Growth Restriction
First Trimester Prediction of Preeclampsia and Fetal Growth Restriction
To evaluate the feasibility of screening for preeclampsia and fetal growth restriction between 11-13+6 weeks' gestation utilizing the combination of uterine artery doppler, maternal blood pressure, maternal characteristics…
- Trial name
- NCT02379494
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Fetal Medicine Foundation
Shoulder Pain Back Pain Postpartum Period, Back Pain
Effects of Body Mechanics Training on Shoulder-Back Pain and Breastfeeding Ergonomics in Breastfeeding Mothers
The research will be conducted as a randomized controlled trial and mothers in the intervention group will receive training on posture correction,breastfeeding positions, and shoulder and back muscle strengthening movements.
- Conditions
- Shoulder Pain Back Pain Postpartum Period, Back Pain, Postpartum Period
- Trial name
- RCT (NCT07104227)
- Testing
- body mechanics training, to inform
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ege University
Assisted Hatching, Advanced Age
The Impact of Assisted Hatching on Pregnancy Outcomes After Vitrified-Warmed Embryo Transfer in Advanced-age Patients
The goal of this clinical trial is to evaluate the effect of laser assisted hatching (LAH) on pregnancy outcomes, with live birth rate as the primary outcome, in advanced age infertile women aged ≥35 years who are undergoing…
- Trial name
- NCT07490561
- Testing
- Laser assisted hatching
- Volunteers
- 916 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Fetal Developmental Abnormality, Fetal Development
Scottish Advanced Fetal Research Study
In-utero exposure to drugs and chemicals through maternal smoking, alcohol use, drug abuse, prescription medicines and occupational/lifestyle exposures is widespread.
- Conditions
- Fetal Developmental Abnormality, Fetal Development, Human, Life Style
- Trial name
- SAFeR (NCT04613583)
- Testing
- SAFeR fetuses
- Where
- United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Mental Disorders, Severe
Measuring Development of Brain Responses to Vocal Sounds in Babies of Mums With Mental Illness
CAPRI-Voc examines the differences in how speech and environmental sounds are processed in the infant brain as they grow from 9 to 12 months.
- Trial name
- CAPRI-Voc (NCT04350294)
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Pregnancy Related
Clatsop Astoria Maternal Partnership Study (CAMPS) - Healthy Eating in Pregnancy Intervention
Purpose of this study is to learn more about how nutritional advice given during pregnancy affects a mother's food choices and her baby's growth.
- Trial name
- CAMPS (NCT03210870)
- Testing
- nutritional education classes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Growth Hormone, Advanced Maternal Age
Effect of GH Supplementation on the Blastocyst Euploid Rate in AMA Patients--A Retrospective Cohort Study
This retrospective cohort study aims to investigate the effects of recombinant human growth hormone (rh-GH) on the euploid status of preimplantation blastocysts in AMA patients.
- Conditions
- Growth Hormone, Advanced Maternal Age, PGT-A
- Trial name
- NCT05574894
- Testing
- Growth hormone, GnRH antagonist
- Where
- China
- Volunteers
- 692 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Gestational Diabetes Mellitus, Neonatal Hyperbilirubinemia
Effect of DCC on Neonatal Jaundice and Blood Gas Analysis in Infants Born to GDM Mothers
Evidence for benefited newborns following delayed cord clamping (DCC), including increasing hemoglobin and hematocrit levels, improving iron stores, and decreasing need for blood transfusion and incidence of intraventricular…
- Conditions
- Gestational Diabetes Mellitus, Neonatal Hyperbilirubinemia, Neonatal Asphyxia
- Trial name
- NCT04369313
- Testing
- delayed cord clamping, early cord clamping
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Depression, Postpartum, Maternal Behavior
The Effect of Baby Massage on Postpartum Depression and Maternal Attachment
This study was conducted to determine the effect of baby massage on postpartum depression and maternal attachment in the postpartum period.
- Conditions
- Depression, Postpartum, Maternal Behavior, Attachment
- Trial name
- NCT05813782
- Testing
- Baby Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Breastfeeding
Effects of Breastfeeding on Maternal Plasma Ghrelin and Peptide Tyrosine Tyrosine (PYY) Levels
Weight retention after pregnancy contributes to increasing rates of obesity. There is evidence that breastfeeding is accompanied from changes in fat mobilisation and fat mass, nevertheless there are no data on the effects of…
- Trial name
- NCT00831818
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Baby Massage, Postpartum Depression
The Effect of Baby Massage Training Given to Pregnant Women on Maternal Attachment and Postpartum Depression
The research to be conducted within the scope of the project will be randomized controlled, and the population of the research will be primiparous pregnant women reached through social media.
- Trial name
- NCT06136520
- Testing
- Baby massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obstetric Labor Complications, Fever
Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia
This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes…
- Trial name
- EIVCIMFAELA (NCT06354582)
- Testing
- Vitamin C Injection, Normal saline
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kunyue Li
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