Clinical trials: Mother
Infections, Cytomegalovirus, Cytomegalovirus Infections
Study of the Transmission of Cytomegalovirus (CMV) Infection From Mother to Foetus
This study is designed to evaluate maternal virological and immunological parameters to determine their ability to predict congenital cytomegalovirus (CMV) infection.
- Trial name
- NCT01251744
- Testing
- Blood sample, Cord blood sample, Saliva swab
- Where
- 9 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- GlaxoSmithKline
Coronary Angioplasty, Bifurcation Coronary Artery Disease
Initial Study of a MOTHER-DAUGHTER SIDE-BRANCH ACCESS™ DES System (FIH Feasibility Study)
This first in human feasibility study is designed to evaluate the feasibility MD-SBA DES in subjects undergoing percutaneous coronary intervention (PCI) to treat bifurcation lesions.
- Conditions
- Coronary Angioplasty, Bifurcation Coronary Artery Disease, Ischemic Heart Disease (IHD), Percutaneous Coronary Intervention (PCI)
- Trial name
- NCT07649798
- Testing
- MD-SBA DES System
- Where
- Paraguay
- Volunteers
- 13 people
- Sponsor
- Advanced Bifurcation Systems Inc.
Pregnancy Related
Correlating Probiotic Dietary Supplements During Pregnancy With Maternal Microbiome Profiles
The overarching goal of this project is to compare the microbiome profiles of healthy pregnant women, both before and after the introduction of a probiotic supplement into the maternal diet.
- Trial name
- NCT03611647
- Testing
- Probiotic
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Effect of Taxes and Subsides on Food Purchases in Mothers
Price Changes and Hypothetical Food Purchases in Adult Grocery Shoppers
The goal of the proposed study is to apply experimental economics in an online grocery store shopping model to examine the effects of pricing on hypothetical food purchases
- Trial name
- Grocery (NCT01619787)
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Endothelial Dysfunction, Childhood Obesity
Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring
The rising worldwide prevalence of obesity and its subsequently rising incidence of concommitant diseases as diabetes and cardiovascular events impose a defiant obstacle for the health care and associated health care costs of…
- Trial name
- EFFECTOR (NCT02992106)
- Testing
- Parental questionnaires, Blood sample, Urine sample
- Where
- Belgium
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Mental Health Wellness, Emotional Problem
Active Pregnancy. Mental and Emotional Health Care to Pregnant Woman During and After Coronavirus (COVID-19)
The complex process of pregnancy and childbirth can determine the future health of mother and child. It is the only vital process that involves the modification of practically all of a woman's body systems in order to sustain…
- Trial name
- GESTACTIVE (NCT05295264)
- Testing
- Moderate exercise program
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
HIV-infected Pregnant Women Who Request HAART From the TRCSPMTCT
The Thai Red Cross Society Prevention of Mother-To-Child Transmission of HIV (TRCS PMTCT) Program
To assess the safety and the efficacy of Highly Active Anti-Retroviral Treatment (HAART) for the Prevention of Mother-To-Child Transmission of HIV (PMTCT)
- Trial name
- NCT02151838
- Where
- Thailand
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Perinatal Depression, Perinatal Anxiety
The DC Mother-Infant Behavioral Wellness Program
This randomized controlled study will examine the effectiveness of patient navigation with culturally adapted cognitive-behavioral interventions and peer support groups for low-income Black/of African Descent pregnant women who…
- Conditions
- Perinatal Depression, Perinatal Anxiety, Prenatal Stress
- Trial name
- NCT05345834
- Testing
- Patient Navigation, Adapted Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Normal Pregnancy
Maternal and Umbilical Cord Hormone Concentrations in Twin and Singleton Pregnancies
This study will examine levels of hormones, such as estrogen and testosterone, in maternal and umbilical cord blood to compare hormones between mothers who are having twins and mothers who are having one baby.
- Trial name
- NCT00341263
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- National Cancer Institute (NCI)
Gestational Diabetes
Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes
Gestational diabetes (GDM) develops during pregnancy and is becoming increasingly common. The condition is associated with adverse outcomes for mother and baby during both the pregnancy and delivery period.
- Trial name
- PAGED-GDM (NCT05981547)
- Testing
- Libre 3 continuous glucose monitoring sensor
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Labor, Second Stage of Labor
The Effect of Chocolate Consumption During Labor on Second Stage Duration
Childbirth is an energy-intensive physiological process, requiring sustained effort comparable in intensity to moderate physical activity.
- Conditions
- Labor, Second Stage of Labor, Pregnancy
- Trial name
- NCT07375836
- Testing
- 50 g of milk chocolate cocoa content 25-30%
- Volunteers
- 180 people
- Sponsor
- Hillel Yaffe Medical Center
Caregiver Burden
10-Week Physical Activity Program for Mothers of Children With Developmental Disabilities
The purpose of this study is to determine the feasibility and acceptability of a 10-week supervised Physical Activity program for mothers of children with developmental disabilities.
- Trial name
- NCT07182071
- Testing
- Physical Activity Program, Waitlist for Physical Activity Program
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Addiction, Substance Abuse Drug Chronic
Stage III Community-based Efficacy Trial for Mothering From the Inside Out
This is a Stage III community-based randomized clinical efficacy trial testing Mothering from the Inside Out (MIO), the first evidence-based parenting intervention designed to be delivered by addiction counselors in addiction…
- Conditions
- Addiction, Substance Abuse Drug Chronic, Child Neglect, Child Neglect Emotional
- Trial name
- NCT02955199
- Testing
- Mothering From the Inside Out (MIO), Parent Education
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Yale University
Health Behavior, Mother-Child Relations
Early Intervention With the Marte Meo Method
Early intervention with the Marte Meo method. Aim to study whether the program have effect on: Maternal confidence, maternal stress, maternal mood (EPDS), dyadic synchrony (Infant care index), and infants social competences…
- Trial name
- TiMM (NCT01799447)
- Testing
- Early intervention
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Congenital Cytomegalovirus Infection, Maternal Cytomegalovirus Infection
A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)
Cytomegalovirus (CMV) is a common virus that usually presents with few if any side effects. When first infected, some people may have symptoms similar to mononucleosis (i.e., fatigue, weakness, fever, swollen glands).
- Trial name
- CMV (NCT01376778)
- Testing
- CMV hyperimmune globulin
- Where
- 16 sites in United States
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Pollutant Effects in the Growth and Development
Environment and Childhood Project Based on a Multicentric Mother-child Cohort of Spain
INMA - INfancia y Medio Ambiente [Environment and Childhood] Project is a research network of several Spanish groups that created a project with the aim to study the paper of the more relevant environmental pollutants in the air…
- Trial name
- INMA (NCT03352960)
- Where
- Spain
- Volunteers
- 2,957 people
- Sponsor
- Basque Health Service
Whooping Cough, Maternal Vaccine Exposure
Immunising Mums Against Pertussis 3
This study will aim to recruit at least 70 children who participated in the iMAP2 study whose mothers received a pertussis vaccine in pregnancy as part of the iMAP2 trial and at least 15 children born to mothers who did not…
- Conditions
- Whooping Cough, Maternal Vaccine Exposure, Immunization; Infection
- Trial name
- iMAP3 (NCT03578120)
- Testing
- Pre-school booster vaccine
- Where
- 3 sites in United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Postpartum Depression
Parenting Skills Group for Mothers With Postpartum Depression
The goal of this longitudinal study is to study the effects of a parenting skills group (Circle of Security Parenting, aka COSP) in mothers with postpartum depression.
- Trial name
- NCT05772897
- Testing
- Circle of Security Parenting program
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Preterm Delivery, Hypothermia
Randomized Controlled Trial of Social Network Targeting in Honduras
Social network targeting strategies can be used to improve the delivery and uptake of health interventions. We will enroll approximately 30,000 individuals into a randomized controlled trial of different targeting algorithms in…
- Conditions
- Preterm Delivery, Hypothermia, Diarrhea, Upper Respiratory Infection
- Trial name
- NCT02694679
- Testing
- CBNH
- Where
- 2 sites in United States, Honduras
- Volunteers
- 31,195 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Use in Childbirth, Smoking Cessation
Fish Oil to Reduce Tobacco Use iN Expectant Mothers Study
The purpose of this feasibility study is to obtain pilot data in preparation for an upcoming R01 submission. The goals of that submission will be to conduct a clinical trial of n-3 LCPUFAs for smoking cessation in pregnant women.
- Conditions
- Tobacco Use in Childbirth, Smoking Cessation, Pregnancy Related
- Trial name
- FORTUNE (NCT03077724)
- Testing
- Fish oil
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
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