Clinical trials: Motion Sickness
Motion Sickness
Motion Sickness Desensitization Using VR
Evaluation of a virtual reality desensitization protocol on subjects with severe motion sickness and study of the role of the emotional component on the effectiveness of the therapy.
- Trial name
- SENSORIEL1 (NCT05628220)
- Testing
- physiotherapy
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Motion Sickness
Motion Sifnos: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness
Randomized, double-blind, placebo-controlled investigating the efficacy of tradipitant in the treatment of motion sickness.
- Trial name
- NCT03772340
- Testing
- Tradipitant
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Vanda Pharmaceuticals
Sea Sickness
Video Head Impulse Test and Seasickness Susceptibility
This a case control study on seasickness susceptibility. 86 healthy maritime personal were divided to seasickness susceptible and non susceptible groups based on a seasickness questionnaire (Golding) and motion sickness score.
- Trial name
- NCT05657340
- Testing
- Video-head impulse testing
- Where
- Israel
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Migraine, Vestibular Migraine
Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma
Multiple sensory cues are typically generated by discrete events, and while they do not reach the cerebrum simultaneously, the brain can bind them temporally if they are interpreted as corresponding to a single event.
- Conditions
- Migraine, Vestibular Migraine, Vestibular Schwannoma, Motion Sickness
- Trial name
- NCT04196933
- Testing
- Temporal Binding Adaptation - PSS training, Temporal Binding Adaptation - PSS adaptation with VI stimulation, Chronic Motion-modulated Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Joint Contractures, Critical Illness
Incidence and Determinants of Joint Contractures in Mechanically Ventilated ICU Patients
This prospective observational cohort study aims to evaluate the incidence and determinants of joint contracture development in mechanically ventilated adult patients admitted to the intensive care unit (ICU).
- Conditions
- Joint Contractures, Critical Illness, Mechanical Ventilation, INTANSIVE CARE
- Trial name
- ICU-CONTRACT (NCT07339397)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Cybersickness, Motion Sickness
Gaze Stabilization vs Oculomotor Exercises on Cybersickness in Computer Users
Many people who use computers for long hours experience "cybersickness" (dizziness, nausea, blurred vision) because their eyes see movement on the screen but their body feels still.
- Conditions
- Cybersickness, Motion Sickness, Vestibular Diseases
- Trial name
- GAZE-CS (NCT07616596)
- Testing
- Gaze Stabilization Exercises, Oculomotor Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Faisalabad
Motion Sickness, Space, Motion Sickness
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
The primary specific aim is to evaluate the use of intranasal scopolamine gel and sensory augmentation as an integrated countermeasure to mitigate motion sickness and enhance sensorimotor performance.
- Conditions
- Motion Sickness, Space, Motion Sickness, Sea Sickness
- Trial name
- NCT05886660
- Testing
- DPI-386 Nasal Gel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Prevention of Nausea Associated With Motion Sickness, Treatment of Nausea Associated With Motion Sickness
Study of the Safety and Efficacy of DPI-386 Nasal Gel on Ocean-Going Vessels
This multi-site Phase 3 clinical trial is a randomized, double-blind, placebo-controlled study to identify the safety and efficacy of DPI 386 nasal gel (intranasal scopolamine gel) for the prevention and treatment of nausea…
- Trial name
- INSCOP (NCT03920644)
- Testing
- Scopolamine Transdermal Patch [Transderm Scop], Scopolamine
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Naval Aeromedical Research Unit, Dayton
Drug Reaction
Motion Sickness Medications and Vestibular Time Constant
Sea sickness represents a major limitation on the performance of ships' crew. One of the challenges faced by the physician in the motion sickness clinic when prescribing anti-sea sickness medication is to select the appropriate…
- Trial name
- NCT03270839
- Testing
- Bonine 25Mg Chewable Tablet, Kwells
- Where
- Israel
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Migraine
Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines?
The purpose of this study is to determine if Rizatriptan, a migraine medication, lowers motion sickness in migraine sufferers.
- Trial name
- NCT00360282
- Testing
- Rizatriptan
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Pittsburgh
Binocular Dysfunction, Vertical Heterophoria
Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria
The purpose of this study is to demonstrate whether, in patients diagnosed with Vertical Heterophoria, the symptoms of dizziness, headache and / or anxiety are reduced or eliminated when a kind of correction called vertical prism…
- Conditions
- Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
- Trial name
- NCT00785135
- Testing
- Lenses containing prismatic correction, Lenses not containing prismatic correction
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Vision Specialists of Birmingham
Motion Sickness
Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness
A multi-center, randomized, double-blind, placebo-controlled study to investigate the efficacy of tradipitant in subjects affected by motion sickness during travel
- Trial name
- NCT04327661
- Testing
- Tradipitant
- Where
- 7 sites in United States
- Volunteers
- 366 people
- Sponsor
- Vanda Pharmaceuticals
Motion Sickness
Clinical Evaluation of the Use of Ginger Extract in the Management of Motion Sickness
This is an open-label, case control study of 180 patients presenting motion sickness, who will perform a motion sickness assessment questionnaire before and after treatment with dry ginger (Z. officinale) extract.
- Trial name
- NCT03755596
- Testing
- Z. officinale extract
- Where
- Brazil
- Volunteers
- 184 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Motion Sickness
Virtual Reality Sickness Questionnaire: Psychometrics in Stroke Patients
The aim of this study is to examine the effects of virtual reality on physiological factors (heart rate, blood pressure) in stroke patients and the psychometric properties of the Virtual Reality Sickness Questionnaire in…
- Trial name
- NCT07297862
- Testing
- Roller Coaster application
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Post-operative Nausea and Vomiting
Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion
The purpose of this study is to clarify whether or not a low-dose propofol infusion can effectively prevent postoperative nausea and vomiting (PONV) in patients who have a documented history of PONV and/or motion sickness.
- Trial name
- PONV (NCT05759481)
- Testing
- Hybrid anesthesia (propofol + sevoflurane), Propofol only TIVA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Milton S. Hershey Medical Center
Motion Sickness
Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray
Part 1, the pharmacokinetic (PK) phase, will expand upon the pilot study conducted at Naval Medical Research Laboratory (NAMRL) and has the goal of determining bioavailability and time to Cmax in a larger representative sample.
- Trial name
- NCT02155309
- Testing
- Scopolamine
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Dizziness, Vertigo
Sensory Training for Visual Motion Sickness
This is a preliminary study to determine the reliability and validity of new tests of orientation and balance, as well as to test the effects of a new treatment for visually induced dizziness.
- Conditions
- Dizziness, Vertigo, Motion Sickness
- Trial name
- NCT04420949
- Testing
- Sensory re-weighting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chronic Nausea
Vagal Auricular Stimulation for Motion Sickness
This study aims to understand the mechanisms underlying nausea response in the brain stem, and the effect of vagal nerve stimulation on nausea.
- Trial name
- VAMOS (NCT07873164)
- Testing
- UROStim
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Motion Sickness
A Comparative Bioavailability and Adhesion Performance Study, Comparing a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants.
In this comparative bioavailability and in vivo skin adhesion study, the impact of minor changes in qualitative composition of polyiso-Butylenes (PIB) from a different supplier and change of the manufacturing line of the micro…
- Trial name
- NCT02839135
- Testing
- Reformulated scopolamine patch, Marketed scopolamine patch
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Motion Sickness
Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion
This is a Phase 3, two-arm, randomized, double-blind, placebo-controlled, single dose efficacy and safety study evaluating the use of a nasal gel to prevent nausea and vomiting associated with motion
- Trial name
- NCT04947423
- Testing
- DPI-386 Nasal Gel
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.