Clinical trials: Motor Activities
Hypertension
Understanding the Exercise-Hypertension Paradox
Hypertension affects 37% of the Veteran population, making it the most common medical condition treated by the VA Health Care System. Physical activity is the first line of defense in the treatment and management of hypertension.
- Trial name
- NCT02034422
- Testing
- Oral Antioxidant, Exercise rehabilitation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Type 2
Evaluation of a Computer-Based, Self-Management Tool for People With Type 2 Diabetes
NEW Brief Summary: Managing diet and physical activity are vital aspects of diabetes self-care; however, people with diabetes often find it difficult to make changes to their usual diet and physical activity patterns.
- Trial name
- LWD (NCT00877851)
- Testing
- Computer-based Program
- Where
- 2 sites in United Kingdom
- Volunteers
- 84 people
- Sponsor
- Queen's University, Belfast
Parkinson's Disease
Genetic Influences on Response to Gait Rehabilitation in Parkinson's Disease
The aging Veteran population, together with high exposure to Agent Orange or other herbicides during military service, has made diseases such as Parkinson's disease (PD), currently affecting more than 80,000 Veterans, a major…
- Trial name
- Gen-Ex (NCT03607695)
- Testing
- Gait training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Stroke, Inflammation
Inflammatory Abnormalities in Muscle After Stroke: Effects of Exercise
The purpose of this study is to first define whether abnormalities of skeletal muscle are related to the presence of inflammation and to poor motor performance and whether this can be modified by exercise interventions.
- Trial name
- NCT00387712
- Testing
- Velocity based treadmill training, Duration based treadmill training
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Long-Term Effects of Torso-Weighting
The goal of this pilot study is to test the protocol for investigating the longer-term effects of torso weighting on physical activity, number of falls, and muscle activation (when muscles turn on and off and how intensely) in…
- Trial name
- TWPS (NCT02743312)
- Testing
- Torso Weights, Fitbit Flex
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- San Francisco State University
Arthritis, Rheumatoid
Effects of a Mobile Application RA Joint Protection and Activity Self-management Program
The goal of this clinical trial is to evaluate the effectiveness of mobile application self-management program (App) for joint protection and physical activity in patients with rheumatoid arthritis.
- Trial name
- NCT05570175
- Testing
- Mobile application RA joint protection and activity self-management program
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Chang Gung Memorial Hospital
Overweight, Obesity
The VA-STRIDE Study
The purpose of the study was to examine the effectiveness of an expert-system, print-based physical activity (PA) intervention delivered to Veterans receiving primary care at the VA Pittsburgh Healthcare System (VAPHS).
- Conditions
- Overweight, Obesity, Sedentary Lifestyle
- Trial name
- NCT00731094
- Testing
- Expert system-based physical activity counseling
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Alcohol Use
Oxytocin, Alcohol Craving, and Intimate Partner Aggression
Alcohol use disorders (AUD) and intimate partner aggression (IPA) frequently co-occur. There are significant health and economic burdens associated with AUD and co-occurring IPA, and little empirical data to guide treatment…
- Trial name
- NCT03046836
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Medical University of South Carolina
Exercise, Bone Resorption
Enhancing Skeletal Adaptations to PTH and Exercise
Exercise is essential for building and maintaining bone mass and strength, but current exercise recommendations for how to achieve this lack detail on the optimal exercise prescription.
- Conditions
- Exercise, Bone Resorption, Bone Formation
- Trial name
- ESkAPE (NCT05029128)
- Testing
- Endurance exercise intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Physical Activity, Weight
Physical Activity and Leisure-time Study (PALS)
Physical inactivity is a major public health problem and a primary contributing factor to the obesity epidemic. While most Americans do not meet the physical activity (PA) guidelines (30 min/day, 5 day/wk), they do report…
- Trial name
- PALS (NCT01342471)
- Testing
- TV commercial stepping, 30-min walk
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Physical Inactivity, Cardiovascular Risk Factor
The Clinical Referral to Activity Study
The main aim of this effort is to test a physical activity intervention, for adult clinical care patients at risk of developing cardiovascular disease.
- Conditions
- Physical Inactivity, Cardiovascular Risk Factor, Obesity, Blood Pressure
- Trial name
- NCT04743856
- Testing
- ActiveGOALSv2, PAT
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Osteoarthritis
Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP)
This is a multi-phase study that will develop and test an osteoarthritis (OA) primary care Physical activity Care Pathway (OA-PCP), a scalable intervention that includes: 1) a practical process for physical inactivity screening…
- Trial name
- NCT03780400
- Testing
- Osteoarthritis Physical Activity Care Pathway
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Multiple Sclerosis
Promoting Physical Activity Behavior in Persons With Multiple Sclerosis
The purpose of this research study is to evaluate whether tailored print material can promote physical activity and exercise, and subsequently improve quality of life and fitness levels among people with multiple sclerosis (MS).
- Trial name
- NCT01572207
- Testing
- Immediate exercise, Delayed exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Western Reserve University
Type 1 Diabetes
Technology-delivered Physical Activity Program for Adolescents With Type 1 Diabetes
This project is comprised of a two-arm randomized control trial (RCT) testing the feasibility, acceptability, and preliminary efficacy of a nationally scalable program, Activate, a 12-week, technology-delivered diabetes…
- Trial name
- Activate (NCT05319600)
- Testing
- Diabetes behavior change skills training, Physical activity promotion program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
Obesity
DVD Lifestyle Intervention
Most Veterans who receive VA healthcare have obesity (41%) or are classified as overweight (37%), putting them at higher risk for multiple serious chronic health conditions.
- Trial name
- D-ELITE (NCT03260140)
- Testing
- behavioral lifestyle intervention
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- VA Office of Research and Development
Motor Activity
Investigating Motor Cortex Processing for Pain Modulation
The purpose of this study is to investigate the effects of different types of interventions (motor learning, somatosensory learning, observation task, mental imagery and tDCS) on the perception of pain and motor cortex…
- Trial name
- NCT01404039
- Testing
- Motor Learning, Somatosensory Learning, Observational Task
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Osteoarthritis, Knee, Osteoarthritis, Hip
Resilience for Older Workers With OA Through Exercise
Exercise is effective at reducing pain while improving physical function. However we do not know if exercise can boost resilience in the workplace, to allow people with osteoarthritis to work as long as they desire.
- Trial name
- NCT02609672
- Testing
- Exercise, No Exercise
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McMaster University
Post-traumatic
Exercise and PTSD in Older Veterans
The purpose of this study is to examine whether posttraumatic stress disorder (PTSD) symptoms impact adherence to a 12-week physical activity program and whether exercise can help improve PTSD symptoms and health outcomes in…
- Trial name
- NCT02295995
- Testing
- Exercise as an Adjuvant Therapy for Veterans with PTSD
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Chronic Heart Failure
Splanchnic Nerve Block for Therapy of Chronic Heart Failure (Splanchnic III)
Splanchnic vasoconstriction may contribute to decompensation of chronic heart failure (HF) via volume redistribution from the splanchnic vascular bed to the central compartment.
- Trial name
- NCT04575428
- Testing
- Splanchnic nerve block
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Athletes Heart, Left Ventricular Hypertrabeculation
Training-induced Increased Left Ventricular Trabeculation
This project will expand on research conducted by the investigators' group, where the investigators have demonstrated increased LV trabeculation, satisfying currently existing criteria for LV Non-Compaction Cardiomyopathy (LVNC)…
- Trial name
- MARATHON (NCT02568072)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- St George's, University of London