Clinical trials: Motor Disability
Functional Disability, Obesity
Effects of a Weight Reduction and Lifestyle Program in Older Adults
This research study will assess the effects of two different programs on weight, body composition, mobility and improved health. Measures of health will include functional abilities, and physical performance.
- Conditions
- Functional Disability, Obesity, Physical Inactivity
- Trial name
- NCT00714506
- Testing
- Diet and physical activity, Physical activity control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Preterm, Extreme Prematurity
Effectiveness of Home Based Early Intervention of Extremely Premature Infant by Parent
This study is to prove the effectiveness of home based early intervention of extremely premature infant by Parent.
- Conditions
- Preterm, Extreme Prematurity, Early Intervention, Developmental Delay
- Trial name
- NCT05334550
- Testing
- Home Based Early Intervention by Parent
- Volunteers
- 110 people
- Sponsor
- Samsung Medical Center
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Chronic Low Back Pain
Effectiveness of Electrical Stimulation or Kinesio Taping on Recovery Disability in Low Back Pain
The purpose of this study is to analyze the effectiveness of electrical stimulation and kinesio taping in combination with exercise in People with Chronic Low Back Pain
- Trial name
- ELECBACK (NCT02812459)
- Testing
- Kinesio taping, Electrical Stimulation
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Universidad de Granada
Exercise, Disability Physical
Testing the Implementation of Movement-to-Music in a Community Fitness Center and Blended Onsite and Teleexercise Class
To prepare for a large scale-up study, the goal of this pilot implementation trial is to examine the feasibility of Movement-to-Music (M2M©) delivery mechanisms through two channels: 1) a group-based M2M© program conducted onsite…
- Trial name
- NCT03991273
- Testing
- Y-M2M©, B-M2M©
- Sponsor
- University of Alabama at Birmingham
Diabetic Adhesive Capsulitis, Frozen Shoulder
Pain Neuroscience Education and Graded Motor Imagery Combined With Conventional Physiotherapy on Diabetic Adhesive Capsulitis
The purpose of this study is to determine the effects of Pain Neuroscience Education (PNE) and Graded Motor Imagery (GMI) combined with conventional physiotherapy on pain, kinesiophobia, central sensitization, functional…
- Conditions
- Diabetic Adhesive Capsulitis, Frozen Shoulder, Type II Diabetes Mellitus
- Trial name
- NCT07763366
- Testing
- Pain Neuroscience Education (PNE), Graded Motor Imagery (GMI), Conventional Physiotherapy
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Musculoskeletal Diseases, Neurological Diseases
Impact of Home-Based Rehabilitation on Motor Function and Mood in Individuals With Disabilities
This study aims to evaluate the impact of a multidisciplinary home-based rehabilitation program on motor function and mood in individuals with moderate neuromusculoskeletal disabilities.
- Trial name
- HB-Rehab (NCT06537791)
- Testing
- Home-Based Rehabilitation Program
- Where
- Chile
- Volunteers
- 270 people
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Developmental Delay, Cerebral Palsy
Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study
Background: People who have cerebral palsy often have difficulty walking and moving their legs. Cerebral palsy is sometimes not identified until a child is almost 2 years of age, which means that early motor skill development can…
- Trial name
- NCT01253083
- Testing
- mobility training with dynamic body weight support
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Disability Physical, Cognitive Impairment
FE-SaLiR: Function Improvement Exercise
As complementary and alternative medicines in both Chinese and Western populations, Wu Qin Xi (the Five Animal Play) and Ba Duan Jin (the Eight Pieces of Brocade) have demonstrated small to medium effects on the improvement of…
- Trial name
- NCT04284137
- Testing
- Modified FE-SaLiR, Unmodified Chinese Medicine Exercise, Active Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas at San Antonio
Charcot Marie Tooth Disease, DIFGAN
Genotype/Phenotype Correlation of MORC2 Mutations
The Microrchidia CW-type zinc finger 2 (MORC2) gene encodes a protein expressed in all tissues and enriched in the brain. It is involved in Charcot-Marie-Tooth disease, with mire than 30 families presenting MORC2 mutations.
- Conditions
- Charcot Marie Tooth Disease, DIFGAN, Developmental Delay (Disorder), Impaired Growth
- Trial name
- PhenoMORC2 (NCT07038239)
- Testing
- Skin biopsy, Blood sample
- Where
- 12 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Intellectual Disability
AI-Supported and Traditional Tennis Training in Individuals With Intellectual Disabilities
This study aims to examine the tennis learning experiences of children with mild intellectual disabilities aged 12-18 years by comparing a real-time pose recognition technology-supported teaching approach with a traditional…
- Trial name
- TENN-ID (NCT07577830)
- Testing
- Technology-Supported Tennis Training (Real-Time Pose Estimation-Based Instruction), Traditional Tennis Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Total Hip Replacement
Comparative Effects of Weight Bearing and Non-weight Bearing Exercises in Patients With Total Hip Replacement
to compare the effects of weight bearing and non-weight bearing exercises on pain, range of motion and disability in patients with total hip replacement
- Trial name
- NCT05375565
- Testing
- weight bearing exercises, non weight bearing exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Physically Disabled
Advanced Virtual Exercise Environment Device for Use by Persons With Physical Disabilities
An Advanced Virtual Exercise Environment Device (AVEED) has been developed that incorporates arm and leg ergometers in conjunction with a virtual reality interface.
- Trial name
- AVEED (NCT02990507)
- Testing
- AVEED: Arm rotation, video display, AVEED: Arm rotation, without video display, AVEED: Leg rotation, arm-energy input, video display
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Spinal Degenerative Disorder, Spinal Stenosis
Physical Activity Intervention for Patients Following Lumbar Spine Surgery
There is a critical need to target physical activity during postoperative management to optimize long-term recovery after lumbar spine surgery.
- Conditions
- Spinal Degenerative Disorder, Spinal Stenosis, Spondylosis
- Trial name
- PASS (NCT04591249)
- Testing
- Physical activity intervention, Usual care
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Vanderbilt University Medical Center
Agraphia
Visual Perceptual Motor Training on Kindergarteners
The study aims to investigate the effects of different visuomotor training programs on children's visuomotor skills and handwriting performance.
- Trial name
- NCT05795738
- Testing
- Chinese character-based visuomotor training program, traditional visuomotor training program
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Low Back Pain
Acceptance and Commitment Therapy Plus Physiotherapy for Chronic Low Back Pain
This study is a randomized controlled trial (RCT) investigating whether adding Acceptance and Commitment Therapy (ACT) to standard physiotherapy provides greater benefits for adults with chronic low back pain than physiotherapy…
- Trial name
- NCT07766616
- Testing
- Acceptance and Commitment Therapy (ACT), Standard Physiotherapy Program
- Volunteers
- 64 people
- Sponsor
- Al-Azhar University
Knee Osteoarthritis, Older Women
Adding Group-Based Pain Neuroscience Education to a Community Exercise Program for Older Women With Knee Osteoarthritis
This pilot trial aimed to estimate preliminary clinical effects and to assess the feasibility of adding group-based pain neuroscience education (PNE) to exercise in women aged ≥60 years with medically diagnosed knee…
- Conditions
- Knee Osteoarthritis, Older Women, Pain, Disability
- Trial name
- NCT07565298
- Testing
- Pain neuroscience education (PNE), Exercise program
- Where
- Chile
- Volunteers
- 19 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Lumbar Spine Disease
Efficacy of Motor Control Exercise Program After Lumbar Spinal Decompression Surgery
The study will be conducted with volunteer patients who have undergone lumbar decompression surgery and who are followed up by the Neurosurgery outpatient clinic of Fethiye State Hospital.
- Trial name
- NCT06014632
- Testing
- Rehabilitation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Muğla Sıtkı Koçman University
AMN, AMN Gene Mutation
A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)
This is a Phase 1/2 randomized, blinded, dose-escalation study to evaluate the safety and efficacy of intrathecal (IT) administration of SBT101, a recombinant adeno-associated virus serotype 9 (AAV9) containing a functional copy…
- Conditions
- AMN, AMN Gene Mutation, X-ALD
- Trial name
- PROPEL (NCT05394064)
- Testing
- SBT101 Treatment
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 9 people
- Sponsor
- SwanBio Therapeutics, Inc.
Low Back Pain
Relationship Between Kinesiophobia, Physical Activity and Disability Level and Pain Management in Patients With CLBP
The aim of this study was to examine the relationship between pain management, kinesiophobia, physical activity and disability level in patients with chronic low back pain (CLBP) in different genders.
- Trial name
- NCT06125496
- Testing
- Pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Alanya Alaaddin Keykubat University