Clinical trials: Motor Disability
AMPD3, OMIM*102772, AMP Deaminase Deficiency, AK1, OMIM *103000, Adenylate Kinase Deficiency
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Background: Pyrimidine and purine metabolism disorders (DPPMs) affect how the body metabolizes chemicals called pyrimidines and purines.
- Conditions
- AMPD3, OMIM*102772, AMP Deaminase Deficiency, AK1, OMIM *103000, Adenylate Kinase Deficiency, AMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency, TPMT, OMIM *187680, Thoipurines, Poor Metabolism of
- Trial name
- NCT06092346
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Development, Infant, Development Delay
The Effect of the Covid 19 Pandemic Process on the Neuromotor Developments of 6-24 Month-old Babies
Development; It covers the areas of physical, mental, emotional and social development. Development in one area affects other areas as well. Infancy is the period in which children grow and develop the fastest.
- Trial name
- NCT05778357
- Testing
- Group1
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Down Syndrome, Activity
Activities and Participation of Children With Down Syndrome
The aim of this study is to examine the activity participation levels of Down syndrome(DS) children and the restrictive or supportive factors affecting their participation levels and to investigate their effects on quality of…
- Conditions
- Down Syndrome, Activity, Participation, Quality of Life
- Trial name
- NCT05152251
- Testing
- Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pelvic Pain, Chronic Pain
Effects of Muscle Energy Technique Versus Aerobic Exercises on Pain and Disability in Patients With Chronic Pelvic Pain
The aim of study is to find out the effects of muscle energy technique versus aerobic exercises on pain and disability in patients with chronic pelvic pain.
- Trial name
- NCT05429957
- Testing
- Muscle Energy Technique, Aerobic Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Development Delay
Task Specific vs Basketball-Based Balance Training in Children With Developmental Delay
To compare the effects of task specific balance training vs task-oriented basketball training on balance and motor skills in children with developmental delay
- Trial name
- NCT07015619
- Testing
- Task Specific Balance Training, Task-oriented Basketball Training
- Volunteers
- 60 people
- Sponsor
- Shalamar Institute of Health Sciences
Intellectual Disability
Therapy-Based Games' Effects on Motor and Cognitive Skills in Intellectual Disabilities
Individuals with intellectual disabilities face challenges in areas of attention, motor skills, and awareness. Among the problems they experience are difficulties in focusing, transitioning from one activity to another…
- Trial name
- NCT06097819
- Testing
- Mobile app-based game group, Supervised combined sensor-based game group, Individualized occupational therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Medipol University Hospital
Chronic Nonspecific Low Back Pain
Dual-Task Core Stabilization Training in Chronic Nonspecific Low Back Pain
This study will investigate whether adding cognitive tasks to core stabilization exercises improves the ability to perform physical and mental tasks simultaneously in adults with chronic nonspecific low back pain.
- Trial name
- DT-CSE (NCT07894965)
- Testing
- Dual-Task Core Stabilization Exercise, Single-Task Core Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karabuk University
Mobility Limitation
Lower Extremity Muscle and Function in the Elderly: Study 2
This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at…
- Trial name
- NCT01614392
- Testing
- High velocity low force Power Training, Low velocity high force Power Training
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tufts University
Development Delay
The Balance Influence of Shoe Inserts on Motor Development Delayed Children
Flatfoot, one of the most common foot problems experienced by preschool-aged children, characterized by the collapse of the foot's medial longitudinal arch.
- Trial name
- NCT02644317
- Testing
- Modified shoe inserts
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chung Shan Medical University
Physical Exercise, Disability Physical
Functional Training Improves the Functional Capacity and Physical Fitness of People Whit Spinal Cord Injury
The aim of this study is to understand the effect of adapted functional training on the physical fitness, functionality and quality of life of individuals with SCI after social distancing due to COVID-19.
- Trial name
- NCT06391658
- Testing
- Functional Training
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Stroke, Aphasia
Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment.
- Conditions
- Stroke, Aphasia, Reading Disorder
- Trial name
- NCT06213272
- Testing
- Phono-Motor Therapy, Aerobic Exercise Training (AET), Stretching
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Kessler Foundation
Cerebral Palsy, Cerebral Palsy (CP)
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated…
- Conditions
- Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
- Trial name
- AIM-High (NCT06857539)
- Where
- 4 sites in Ireland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Cork
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
School-based Physical Activity Intervention for Obesity Among Adolescents With Intellectual Disability in Hong Kong
Considering that children with intellectual disability (ID) might be more vulnerable to obesity than their counterparts in the general population.
- Trial name
- NCT04463069
- Testing
- Adapted physical activity
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Osteoarthritis, Hip, Osteoarthritis, Knee
Tai Chi or Hydrotherapy for People With Osteoarthritis of the Hip(s) or Knee(s)
The aim of this study is to determine, in the framework of a randomized controlled clinical trial, whether Tai Chi can affect measurable improvements in self-reported outcomes such as pain, physical function and psychological…
- Trial name
- NCT00123994
- Testing
- Tai Chi classes, Hydrotherapy classes
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- St George Hospital, Australia
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Cerebral Palsy, Child, Preschool
Effect of Power Wheelchairs on the Development and Function of Young Children With Severe Physical Disabilities
Self-produced locomotion often is limited in children with cerebral palsy and other conditions that cause severe motor impairments.
- Trial name
- NCT01115998
- Testing
- Power wheelchair, No power wheelchairs
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Shoulder Impingement Syndrome
Exercise Application in the Treatment of Patients With Subacromial Pain Syndrome
This study evaluate the effectiveness of adding neuromuscular exercises with tactile, visual and auditory feedback to a scapula-focused treatment, both emphasizing the periscapular muscles on improvement of disability in patients…
- Trial name
- NCT02695524
- Testing
- Scapula-focused exercises, Motor control exercises
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Down Syndrome
Promoting Health Through Parent Empowerment and the Activation of Routines (PrO-PEAR)
This study will examine the feasibility of the Promoting Health through Parent Empowerment and the Activation of Routines (Pro-PEAR) intervention using a open case-series for intervention optimization followed by a pilot RCT in…
- Trial name
- Pro-PEAR (NCT05020366)
- Testing
- Promoting Health through Parent Empowerment and the Activation of Routines, Enhanced Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Tetraplegia
NeuroCognitive Communicator: Safety Study
Individuals suffering from tetraplegia as a result of cervical spinal cord injury, brainstem stroke, or amyotrophic lateral sclerosis (ALS) cannot independently perform tasks of daily living.
- Trial name
- NCC-1701 (NCT03100110)
- Testing
- NeuroCognitive Communicator
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Ottawa Hospital Research Institute