Clinical trials: Motor Disorder
Diabetic Neuropathies
Effect of Foot Muscle Energy Technique in Patients With Diabetic Neuropathy
Foot muscle energy technique and conventional physical therapy program administered in patients with type 2 Diabetic Neuropathy.
- Trial name
- NCT05790421
- Testing
- Foot Muscle Energy Technique, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- October 6 University
Amyotrophic Lateral Sclerosis, Neurodegenerative Disease
Assessment of the Cyberlink Control System for Use by the Amyotrophic Lateral Sclerosis (ALS) Patient
The goal of this project is to determine whether this device is a practical and realistic means for ALS patients to operate their computers with only the use of facial, brainwave, and eye movements.
- Conditions
- Amyotrophic Lateral Sclerosis, Neurodegenerative Disease, Motor Neuron Disease
- Trial name
- NCT00718016
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Drexel University College of Medicine
Restlessness
Loxapine in the Management of Restlessness During Mechanical Ventilation Weaning
This study aims to assess the efficacy of a drug (loxapine, a neuroleptic) in calming patients down in a situation of restlessness during mechanical ventilation weaning.
- Trial name
- Sevralox (NCT01193816)
- Testing
- loxapine
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Whole Body Vibration in Chronic Stroke
This study is a randomized controlled trial aimed to assess the efficacy of a 10-week whole body vibration training program on physical functioning, societal participation and quality of life in individuals with chronic stroke.
- Trial name
- NCT01822704
- Testing
- Low intensity whole body vibration, High intensity whole body vibration, Leg exercises
- Where
- Hong Kong
- Volunteers
- 81 people
- Sponsor
- The Hong Kong Polytechnic University
Unilateral and Bilateral Cerebral Palsy
Quality of Life in Children With Cerebral Palsy
Cerebral Palsy (CP) is an umbrella term that defines a group of permanent disorders of movement and posture, happening during the developing foetal or infant brain.
- Trial name
- NCT06288958
- Testing
- Quality of Life and social participation in Italian children with CP
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Fondazione Stella Maris
Spinal Muscular Atrophy (SMA)
Virtual Reality for the Mitigation of Anxiety During Intrathecal Administration in Participants With Spinal Muscular Atrophy
The primary objective of the study is to evaluate anxiety level during intrathecal administration (IT) under standard of care (SOC) and virtual reality (VR) conditions using a reliable self-rating scale.
- Trial name
- REALITY (NCT05354414)
- Testing
- Virtual reality, Standard of Care
- Where
- 12 sites in France
- Volunteers
- 63 people
- Sponsor
- Biogen
Amyotrophic Lateral Sclerosis
Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)
This was a parallel treatment, Phase 2, randomized, double-blind study to assess the efficacy, safety, tolerability, PK, and PD of twice daily (BID) oral SAR443820 compared with placebo in male and female participants, 18 to 80…
- Trial name
- HIMALAYA (NCT05237284)
- Testing
- SAR443820
- Where
- 63 sites in United States, Belgium and 11 more
- Volunteers
- 305 people
- Sponsor
- Sanofi
Sarcopenia, Muscular Atrophy
Exercise and Nutrition Interventions in Age-related Sarcopenia
This project will investigate the synergistic effects of Aerobic and Resistance type Exercise, in combination with Protein Supplementation, on; Body Composition, Musculoskeletal Functioning, Nutritional Status and Quality of Life…
- Trial name
- NCT02912130
- Testing
- Protein Supplementation, Aerobic Exercise, Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Liverpool Hope University
Multiple Sclerosis
Effect of Motor Entrainment to Auditory Cues and Music During Walking on Quality of Movement and Perceived Fatigue in Persons With Multiple Sclerosis (PwMS)
The study investigates the effect of different conditions of auditory cueing and music on walking quality and perceived fatigue in persons with multiple sclerosis compared to healthy controls.
- Trial name
- NCT03281330
- Testing
- auditory cues and music during walking
- Where
- 3 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Hasselt University
Athetoid CP, Cerebral Palsy (CP)
Comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children With Athetoid Cerebral Palsy: A Randomized Controlled Trial
This is an RCT aiming to explore the comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children with Athetoid Cerebral Palsy
- Trial name
- NCT07611565
- Testing
- Sensory Integration Therapy and Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Ibadat International University, Islamabad
Focus Type 2 Diabetes Related Chronic Kidney Disease
Diabetic Kidney Disease: Influence of Exercise Therapy on Physical and Vascular Function.
The general objective is to investigate the effect of a 12 week walking exercise program on vascular endothelial function, arterial stiffness/compliance, and vascular health biomarkers in men and women with pre-dialysis type 2…
- Trial name
- DKD-EXT (NCT02112071)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Minnesota
Chronic Disease
Effects of Tele-yoga in Long-term Conditions
Long-term illness is common in the Swedish population, especially among older people. These conditions are often associated with impaired quality of life due to high physical and psychological symptom-burden.
- Trial name
- TELEYOGA (NCT03703609)
- Testing
- Tele-yoga
- Where
- 4 sites in Sweden
- Volunteers
- 311 people
- Sponsor
- Linkoeping University
Amyotrophic Lateral Sclerosis
The E-health Application To Modify ORal Energy Intake and Measure Outcomes REmotely in ALS Clinical Trial (EAT MORE2)
This is phase IIa feasibility and tolerability study of a mobile health (mHealth) application designed to study the effects of remote dietary counseling on disease progression and quality of life.
- Trial name
- EAT MORE2 (NCT04051333)
- Testing
- ALS Nutrition App (MyDataHelps platform)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Colon Cancer
NIMA-Colon Cancer Study
The goal of this study is to evaluate the effects of nutritional supplementation and physical activity interventions on recovery, muscle strength, nutritional status, inflammation, and metabolic health in adults with colon cancer…
- Trial name
- NIMA (NCT07534852)
- Testing
- Standard hypercaloric-hyperproteic nutritional supplementation, HMB-enriched hypercaloric-hyperproteic nutritional supplementation with vitamin D and calcium, Supervised exercise program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Non Invasive Ventilation, Spinal Muscular Atrophy
Exploratory Study of Respiratory Bacterial Infections or Superinfections and Colonizations in Patients With Spinal Muscular Atrophy Under NIV
SMA (Spinal Muscular Atrophy) is a rare neuromuscular disease characterized by motoneuron damage. Symptoms consist of respiratory involvement with numerous respiratory infections and eventually respiratory failure, for which NIV…
- Conditions
- Non Invasive Ventilation, Spinal Muscular Atrophy, Respiratory Bacterial Infection
- Trial name
- AVNIR (NCT05712330)
- Testing
- non invasive ventilation samples, patient samples, parent questionnaire
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Quality of Life, Exercise
The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise
Treatment of COPD patients depends on the stage of the disease. First of all it is strongly recommended quit smoking, then bronchodilators drugs are added.
- Trial name
- NAC (NCT00476736)
- Testing
- Effect on small airways (N-Acetylcystein)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Myocardial Ischemia, Physical Exercise
Randomized Clinical Trial by Conglomerates on the Efficacy of Maintenance of Physical Exercise in Myocardial Ischemia
Main objective: To assess the efficacy of a phase III cardiac rehabilitation program (CRP), based on counseling in the maintenance of physical exercise (time of physical exercise per week) for patients with myocardial ischemia…
- Trial name
- CarPE3 (NCT04251611)
- Testing
- Maintenance of physical exercise
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Núria Santaularia Capdevila
Post COVID-19 Condition
Multidisciplinary Day-hospital Versus Waiting List Management of Post-COVID-19 Persistent Symptoms (ECHAP-COVID)
After an acute episode of COVID-19, many patients experience persistent or recurrent symptoms with substantial impairment of their quality of life.
- Trial name
- ECHAP-COVID (NCT05532904)
- Testing
- Personalized multidisciplinary day-hospital intervention
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myofascial Pain Syndrome
Dry Needling and High Intensity Laser Therapy in Treatment of Myofascial Pain Syndrome
108 myofascial pain syndrome (MPS) diagnosed patients will be randomly divided into 3 groups. To groups; exercise, exercise+high-intensity laser therapy (HILT) and exercise+dry needling will be applied.
- Trial name
- NCT05078333
- Testing
- dry needle, high intensity laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Emine Dundar Ahi
Stroke, Hemiparesis
Telerehabilitation Through Serious Games in Virtual Reality in a Stroke Population (AutoRReVi)
After a stroke, individuals present with motor and/or cognitive impairments. These impairments limit activity, restrict participation and affect quality of life.
- Conditions
- Stroke, Hemiparesis, Cognitive Impairment, Healthy Subjects
- Trial name
- AutoRReVi (NCT04694833)
- Testing
- Motor and cognitive virtual reality-based assessments, Motor and cognitive virtual reality-based serious games
- Where
- Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain