Clinical trials: Motor Function
Stroke, Rehabilitation; Tobacco Use
Quantitative Prognostic Analysis of Upper Limb Motor Dysfunction After Stroke
30% - 66% of stroke survivors have upper limb dysfunction. Effective rehabilitation can improve the prognosis, but the rehabilitation resources are limited.
- Conditions
- Stroke, Rehabilitation; Tobacco Use, Upper Extremity Dysfunction, Prognosis
- Trial name
- NCT05410054
- Testing
- no intervention
- Volunteers
- 178 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Parkinson Disease (PD)
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS)-Primed Self-controlled Practice in People With Parkinson's Disease
Parkinson's disease (PD) is commonly associated with impaired motor learning and reduced motivation, both of which can negatively influence rehabilitation outcomes.
- Trial name
- NCT07832695
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Physical therapy
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
Effects of Lokomat-Robot Assisted Gait Training on Gross Motor Function in Children and Young Adults With Cerebral Palsy
This single-center, controlled, delayed-intervention, quasi-experimental study evaluates the effectiveness of Lokomat®-assisted robotic gait training on gross motor function and health-related quality of life in children and…
- Trial name
- NCT07732205
- Testing
- Sessions with Lokomat robot-assisted system, Control arm
- Where
- Hungary
- Volunteers
- 96 people
- Sponsor
- Semmelweis University
Peritoneal Dialysis, Kidney Failure, Chronic
Exercise in Peritoneal Dialysis Patients (PDEX)
Patients with end-stage kidney disease (ESKD) receiving peritoneal dialysis (PD) are physically inactive, resulting in poor physical function and reduced quality of life.
- Trial name
- PDEX (NCT03980795)
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Satellite Healthcare
Spinal Muscular Atrophy
Responsiveness and Validation Study of MFM-32 in SMA Patients Treated With Nusinersen
The Motor Function Measure (MFM), a reliable tool assessing motor function and its progression in most neuromuscular diseases, is widely used in France in many teams.
- Trial name
- NusiMFM (NCT04602195)
- Where
- 10 sites in France
- Volunteers
- 33 people
- Sponsor
- Hospices Civils de Lyon
Cognitive Impairment
The Mental Activity and eXercise Trial for Seniors
The primary objective of this study is to conduct a randomized, controlled trial to determine whether engaging in mental activity or exercise, either alone or in combination, improves cognitive function in non-demented, inactive…
- Trial name
- MAX (NCT00522899)
- Testing
- Group 1, Group 2, Group 3
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of California, San Francisco
Stroke, Cerebrovascular Accident
Effects of tVNS and mCIMT in Chronic Stroke
Stroke is a leading cause of death and disability worldwide, resulting in significant physical and cognitive impairments. Arm weakness is most common after stroke and its treatment is recognized as an area of considerable need.
- Trial name
- NCT07272239
- Testing
- Transcutaneous Vagus Nerve Stimulation, Modified Constraint Induced Movement Therapy with Routine Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Cerebral Palsy, Spastic, Diplegic
Potential Benefits of Home Based Exercise Programs in the Management of Spastic Cerebral Palsy
The study will be conducted to see the potential benefits of home based exercise program comprising routine physical therapy and traditional massage in the management of spastic cerebral palsy (CP).
- Trial name
- HEP&CP (NCT05111236)
- Testing
- Routine physical therapy, Traditional massage
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- National Institute of Rehabilitation Medicine, Islamabad, Pakistan
Parkinson's Disease
Non-contact Boxing Training and Traditional Therapeutic Exercise for Persons With Parkinson's Disease
The primary purpose of this study is to compare the effects of a non-traditional boxing training program to a traditional therapeutic exercise program on activity and participation outcomes in persons with Parkinson's disease.
- Trial name
- NCT01014663
- Testing
- Traditional Therapeutic Exercise, Non-Contact Boxing Training
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Indianapolis
Huntington's Disease (HD), Exergame
Comparison of Two Cognitive-Motor Rehabilitation Approaches Via Exergames: a Study of Cognitive, Motor and Behavioral Functions in Huntington's Disease Patients
Huntington's disease (HD) is a rare, hereditary neurodegenerative disorder. It generally manifests itself between the ages of 40 and 50, and results in motor impairment (choreic movements, balance disorders, gait disorders…
- Trial name
- CARE-MH (NCT06807892)
- Testing
- Synergistic management, Sequential management
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Fibromyalgia, Pain
Men With Fibromyalgia or Chronic Widespread Pain - Effect of Exercise on Symptoms and Body Functions
A controlled randomised trial (CRT). 60 men who fulfil the ACR-criteria for Fibromyalgia or Chronic Widespread Pain (Wolfe 1990) participate in the study.
- Trial name
- NCT01278641
- Testing
- Graded strength resistance training program, Temperate pool exercise program
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Göteborg University
Upper Limb Motor Dysfunction, Stroke
ZEPU-SGI1PLUS Hand Training Study (ZEPUSGI1RCT)
The goal of this pilot randomized controlled trial is to learn whether the ZEPU-SG1PLUS Hand Functional Comprehensive Training System - a robotic device used alongside standard rehabilitation - is safe, feasible, and helpful for…
- Conditions
- Upper Limb Motor Dysfunction, Stroke, Incomplete Spinal Cord Injury, Traumatic Brain Injury
- Trial name
- NCT07739264
- Testing
- ZEPU-SG1PLUS Hand Functional Comprehensive Training System, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Exercise Therapy
Virtual Reality Exercise Program for People with Type 2 Diabetes
The purpose of this study is to examine the effectiveness of a virtual reality (VR) based rehabilitation protocol for improvement of blood glucose control and exercise compliance of patients.
- Trial name
- NCT05794009
- Testing
- Immersive Virtual Reality Exercise (IVRE), Home Exercise
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- The Hong Kong Polytechnic University
Multiple Sclerosis
Non-invasive Spinal Cord Stimulation for Spasticity Control and Augmentation of Voluntary Motor Control in Individuals With Multiple Sclerosis
Epidural spinal cord stimulation (SCS) is currently regarded as one of the most promising intervention methods to improve motor function in individuals with severe spinal cord injury.
- Trial name
- noSpasMS (NCT04486209)
- Testing
- transcutaneous spinal cord stimulation
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Medical University of Vienna
Non-communicable Diseases (NCD), Addiction to Opioids
Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants
The existence of social inequalities is a major global issue and a salient challenge for the European Union. During COVID-19 pandemic, health disparities became more evident.
- Conditions
- Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders
- Trial name
- CHANCE (NCT07558187)
- Where
- 5 sites in Greece
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Coenzyme Q10, Oxidative Stress
Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes
It is proposed to establish a group of subjects composed of 10 healthy individuals of> 50 years and <65, physically active, without metabolic or inflammatory pathology.
- Conditions
- Coenzyme Q10, Oxidative Stress, Aging
- Trial name
- CoQ10Sport (NCT03893864)
- Testing
- Administration of a product with Fitosomed Ubiquinone, Coenzyme Q10 level in muscle biopsies, Coenzyme Q10 level in plasma, blood cells, urine cells
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Centre d'Alt Rendiment
Obstetric Brachial Plexus Injury, Birth Related Brachial Plexus Injury
Investigating the Effectiveness of Graded Motor Imagery Training in Children With Obstetric Brachial Plexus Injury
The aim of this study is to investigate the effect of graded motor imagery training on upper extremity motor function, proprioception, functional mobility, balance and quality of life in patients with obstetric brachial plexus…
- Conditions
- Obstetric Brachial Plexus Injury, Birth Related Brachial Plexus Injury, Neonatal Brachial Plexus Palsy
- Trial name
- NCT06966544
- Testing
- Conventional Physiotherapy, Graded Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Bakircay University
Depressive Disorder, Major
Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation
A large body of evidence on depression heterogeneity point to an "immunometabolic" subtype characterized by the clustering of immunometabolic dysregulations with atypical behavioral symptoms related to energy homeostasis.
- Trial name
- MOTIVADE (NCT05909267)
- Testing
- L-dopa/Carbidopa
- Where
- Germany
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Obesity, Overweight
Effective Training in Overweight and Obese People
The aim is to come to a consensus about how to prescribe exercise training that actually helps overweight and obese people. Thus, the present study determines the effects of several types of exercise training to define the one…
- Trial name
- NCT00218920
- Testing
- Strength training, continuous moderate-intensity aerobic training, high-intensity interval aerobic training
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Cerebral Palsy (CP), Spastic Quadriplegia
Impact of Task-Specific Electrical Stimulation on Upper Limb Functional Motor Skills in Children With Spastic Quadriplegia
Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018) .
- Conditions
- Cerebral Palsy (CP), Spastic Quadriplegia, Upper Limb Function, Functional Motor Disorder
- Trial name
- NCT07631390
- Testing
- The Chattanooga Continuum™, Designed Physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University