Clinical trials: Motor Impairment
Multiple Sclerosis, Fatigue
The Impact of Exercise Training on Living Quality in Multiple Sclerosis Individuals
The most common symptom displayed in patients with multiple sclerosis (MS) is a pronounced sense of fatigue that can have negative effect on functional ability and quality of life (QOL).
- Conditions
- Multiple Sclerosis, Fatigue, Mental Status Change, Physical Disability
- Trial name
- NCT03222596
- Testing
- Exercise training
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Mild Cognitive Impairment
Intervention to Reduce Sedentary Time
The purpose of this study is to determine whether the researchers can help people change the amount of time they spend in sitting activities and whether this change might improve health outcomes.
- Trial name
- ReST-MCI (NCT02878486)
- Testing
- Jawbone Up, Physical Activity Education, ActivPAL
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Kansas Medical Center
Instability; Back
Neuromuscular Electrical Stimulation and Motor Control
Phase I, this study aims to:- 1. Establish intra- and inter-rater reliability and minimal detectable change of ultrasound imaging measurement 2.
- Trial name
- NCT03786627
- Testing
- Combined NMES and motor control
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Ischemic Stroke, Motor Deficits
Effect of Vagus Nerve Stimulation Via the Outer Ear on Motor and Cognitive Deficits After Ischemic Stroke
The goal of this clinical trial is to learn if transcutaneous auricular vagus nerve stimulation (taVNS) works to treat motor and neurocognitive deficits after ischemic stroke when applied within 30 days after onset of stroke.
- Conditions
- Ischemic Stroke, Motor Deficits, Cognitive Impairment, Vagus Nerve Stimulation
- Trial name
- EVAMOS (NCT06822140)
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- Switzerland
- Volunteers
- 144 people
- Sponsor
- Rheinburg-Klinik
Multiple Sclerosis, Physical Activity
Exercise and Learning and Memory in Multiple Sclerosis
The two primary study objectives involve examining the effects of treadmill walking exercise training versus stretching-and-toning activities on the primary and secondary outcomes.
- Conditions
- Multiple Sclerosis, Physical Activity, Memory Impairment, Cognitive Change
- Trial name
- NCT03319771
- Testing
- Treadmill Walking Exercise Training, Stretching-and-toning Exercise Training
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Alabama at Birmingham
MCI
Motor-cognitive Interventions Are Effective in Improving Cognitive Function in Older Adults With Mild Cognitive impairment--a Chinese Sample
Mild cognitive impairment (MCI) is a syndrome that occurs in the preclinical stage of Alzheimer, and early intervention can be effective in preventing Alzheimer, but further research is needed on intervention methods.
- Trial name
- NCT05764421
- Testing
- motor-cognitive intervention
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Jinxuan Cheng
Alzheimer Disease, Traumatic Brain Injury
Olfactory Deficits in Neurologic Disease
The goal of this study is to examine olfactory function in preclinical subjects or individuals with neurological diseases such as Probable Alzheimer's Disease (PRAD), Frontotemporal Dementias (FTD), Dementia with Lewy Bodies…
- Conditions
- Alzheimer Disease, Traumatic Brain Injury, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
- Trial name
- NCT05019014
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Shoulder Posterior Instability, Shoulder Anterior Instability
Evaluating Upper Limb Movement Precision With AuReha in People With One-Sided Motor Impairment
The clinical investigation is designed as a controlled, two-arm, intra-patient, non-randomized interventional study aimed at assessing the capabilities of the AuReha system in detecting upper limb movement precision in patients…
- Conditions
- Shoulder Posterior Instability, Shoulder Anterior Instability, Shoulder Anterior Latarjet Instability, Adhesive Capsulitis, Shoulder
- Trial name
- NCT07133100
- Testing
- Upper limb rehabilitation wearable device
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- DigitalRehab
Cognitive Impairment, End-Stage Renal Disease
Impact of Exercise on Cognitive Impairment in End-Stage Renal Disease
The purpose of this study is to evaluate the impact of 12 weeks of exercise on cognition in patients with end stage renal disease.
- Trial name
- NCT02145702
- Testing
- Aerobic Exercise, Standard Care Dialysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Stroke
Mirror Therapy in Pos Stroke Individuals
To evaluate the benefits of Mirror Therapy (MT) and motivation in patients with different levels of post-stroke motor impairment with two different therapy protocols.
- Trial name
- NCT03175237
- Testing
- Mirror Therapy
- Volunteers
- 27 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Dysphagia, Oral Phase, Stroke, Ischemic
Lingual Endurance Exercise in Treating Post-Stroke Dysphagia
Aim 1: Determine feasibility of lingual endurance training for individuals with persistent dysphagia after ischemic stroke. Primary outcome measures: % patient adherence (# of attempted repetitions/# prescribed repetitions) and %…
- Trial name
- NCT05523973
- Testing
- Lingual Endurance Training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
Mild Cognitive Impairment
The Effectiveness of Combining Physical Exercise and Cognitive Training for Individuals With Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a syndrome defined as an intermediate stage between cognitively intact and clinically diagnosed dementia.
- Trial name
- NCT03619577
- Testing
- Sequential training
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Mild Cognitive Impairment
Effects of Cognitive-motor Training on Cognition, Depression and Daily Functioning in Patients With Mild Cognitive Impairment (MCI)
This randomized controlled trial evaluated the effectiveness of an immersive virtual reality (IVR) application (focused on a daily activity) to train cognitive functions and its impact on depression and the ability to perform…
- Trial name
- NCT06313931
- Testing
- cognitive training via immersive virtual reality, cognitive training via paper and pencil, motor stimulation
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad de Zaragoza
To Evaluate Effectiveness of the Gait Trainer in Increasing the Functionality and Spatiotemporal Parameters of Gait of 4 Patients.
Evaluation of the Effectiveness of a Novel Gait Trainer in Increasing the Functionality of Motor Impaired Patients: Pilot Study
Unstrained ambulation is the main goal of gait rehabilitation for preventing fatigue and increasing functionality in patients with gait deficiencies.
- Trial name
- NCT01906723
- Testing
- Walker
- Where
- Israel
- Volunteers
- 4 people
- Sponsor
- Hadassah Medical Organization
Stroke Hemorrhagic, Stroke, Ischemic
The Role of Cognition in Motor Learning After Stroke
Stroke leads to lasting problems in using the upper limb (UL) for everyday life activities. While rehabilitation programs depend on motor learning, UL recovery is less than ideal.
- Conditions
- Stroke Hemorrhagic, Stroke, Ischemic, Cognitive Impairment
- Trial name
- NCT05268861
- Testing
- Error Augmentation Feedback, No Error Augmentation Feedback
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McGill University
Stroke, Hand Functions
Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients
Hand and arm function is often significantly impaired in stroke patients, making its recovery a primary goal in rehabilitative treatment.
- Conditions
- Stroke, Hand Functions, Cerebrovascular Disease, Brain Diseases
- Trial name
- NCT06809959
- Testing
- In-phase-tACS, Out-of-phase-tACS
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cognitive Impairment, Dementia
Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial
Dementias secondary to cerebrovascular diseases are of significant epidemiological and clinical relevance. As a result, the management of individuals with comorbid dementia should involve early diagnosis, effective treatment, and…
- Conditions
- Cognitive Impairment, Dementia, Comorbidities and Coexisting Conditions, Vascular Dementia
- Trial name
- RCTCogRehab (NCT05954741)
- Testing
- Motor rehabilitation alone, Motor rehabilitation and Cognitive rehabilitation (paper-based), Motor rehabilitation and cognitive rehabilitation (digital-based)
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Diabetes Mellitus Type 2, Impaired Balance in Elderly
Improvement Through Movement - Balance Control and Somatosensory Function in People With Diabetes Mellitus Type 2
This study focuses on improving balance control and somatosensory functions in individuals aged 60 years and older with diabetes mellitus tyoe 2 (DMT2).
- Conditions
- Diabetes Mellitus Type 2, Impaired Balance in Elderly, Somatosensory Disorders, Balance Control in Elderly
- Trial name
- NCT07786194
- Testing
- Balance control and exercise training, Relaxation and exercise training
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universiteit Antwerpen
Deglutition Disorders, Impaired Cognition
Dysphagia in Elderly Medical Patients
Dysphagia in hospitalized elders is associated with less positive outcomes in rehabilitation, increased likelihood of readmission, increased comorbidity and mortality, and increased length of hospital stay.
- Conditions
- Deglutition Disorders, Impaired Cognition, Physical Activity, Complete Immobility Due to Frailty
- Trial name
- DEM (NCT01006330)
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Herlev Hospital
Physically Disabled
Evaluation of the Lakeshore Online Fitness Program
The purpose of this project is to test feasibility of an online platform that delivers virtual exercise programs for individuals with physical disabilities.
- Trial name
- NCT05138809
- Testing
- Exercise
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Alabama at Birmingham