Clinical trials: Mouth Disease
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Acute Pancreatitis
Early Oral Carbohydrate Solution vs Clear Liquid Diet in Acute Pancreatitis
Background: Acute pancreatitis (AP) is an inflammatory condition associated with increased metabolic demands and negative nitrogen balance, making early nutritional support a critical component of management.
- Trial name
- NCT07375186
- Testing
- Oral Carbohydrate Solution, Clear Liquid diet
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Jinnah Hospital
Gingivitis, Periodontitis
Bacteremia in Periodontal Patients
Bacteremia represents the presence of live germs in the blood stream. Patients with gum disease show damaged tissues and seem to be more susceptible to bacteremia.
- Trial name
- NCT02215473
- Testing
- Chlorhexidine gluconate mouth rinse, Periodontal instrumentation
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Taubate
Psoriasis
Comparison Study of Psoriasis Severity Assessment Tools
This study evaluates the performance of objective psoriasis severity assessment tool compared with a subjective assessment tool for the assessment of the improvement of psoriasis after oral cyclosporine A or methotrexate…
- Trial name
- NCT02655705
- Testing
- Cyclosporine A, Methotrexate
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Periodontal Diseases
Controlled Study Comparing REPaiR® and MIST Therapies for Treatment of Periodontitis
A comparison of laser (REPaiR) compared with minimally invasive surgical therapy for moderate to severe periodontal disease.
- Trial name
- NCT04169139
- Testing
- MIST (minimally invasive surgical therapy)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- McGuire Institute
Cardio-vascular Disease, Stroke Cancer
Improving Access to Control of Diseases for Women
The aim of this study is to evaluate the feasibility and acceptability of the model of delivering CHW-driven home-based comprehensive NCD control services aimed to prevent premature deaths from cardio-vascular diseases, stroke…
- Conditions
- Cardio-vascular Disease, Stroke Cancer, Breast Cancer, Oral Cancer
- Trial name
- IMPACD (NCT03604939)
- Testing
- Evaluation of social, cultural and behavioral factors, Evaluation of the feasibility and acceptability of delivery of early detections services
- Where
- India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Parkinson Disease
A Single-dose Study to Investigate the Tolerance and Pharmacokinetics of Finamine Tablets in China
Design：Randomization, double-blind, single-center, single-dose, dose-escalation , placebo and parallel control Objectives： 1. To investigate the tolerability and safety of Chinese healthy adult subjects after a single oral…
- Trial name
- NCT04162275
- Testing
- Finamine tablets
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yiling Pharmaceutical Inc.
Healthy Volunteers
Multiple Ascending Dose and DDI Study
Part A will investigate the safety, tolerability, PK and PD of PF-06835919 administered for 14 days in a multiple ascending dose design.
- Trial name
- NCT03031119
- Testing
- PF-06835919, atorvastatin
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Pfizer
Parotid Tumors, Facial Nerve Paresis
Intra-parotid Facial Nerve Imaging in Parotidectomy
In this study, the investigators will evaluate the clinical usefulness of 3 dimensional double echo steady state MRI (3D-DESS MRI) for functional preservation of the facial nerve during parotidectomy.
- Trial name
- NCT03822728
- Testing
- 3D-DESS MRI (3 dimensional double echo steady state MRI)
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Samsung Medical Center
Pompe Disease
First-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administered With Oral AT2221
This is an international, multi-center, open-label study designed to evaluate if the co-administration of investigational new drugs ATB200 and AT2221 is safe in adults with Pompe disease.
- Trial name
- NCT02675465
- Testing
- ATB200, AT2221
- Where
- 19 sites in United States, Australia and 4 more
- Volunteers
- 29 people
- Sponsor
- Amicus Therapeutics
Obstetric Labour, Premature, Premature Ejaculation
A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.
A study conducted on healthy volunteers to determine the safety, tolerability and affect on the human body by experimental drug GSK557296.
- Trial name
- NCT00549211
- Testing
- GSK557296
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Kidney Injury
Oral Salt and Water to Prevent Contrast Nephropathy
The purpose of this pilot trial is to determine the safety and feasibility of using oral salt and water loading compared to intravenous saline for the prevention of contrast-induced acute kidney injury in patients with chronic…
- Trial name
- NCT02084771
- Testing
- Intravenous Saline, Oral Salt and Water
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Stable Angina Pectoris, Periodontitis
Effect of Periodontal Therapy on Asprosin in Stable Angina
This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis.
- Trial name
- NCT07591844
- Testing
- Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Peri-Implantitis, Peri-implant Mucositis
Evaluation of the Patient's Risk Profile Using the Peri-implantitis Risk Diagram
Various risk factors defined in the literature should be eliminated in order for the patient to be able to use implant-supported prostheses for a longer period of time.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Dental Implant Failed
- Trial name
- NCT05618171
- Testing
- Evaluation of the patient's pre- and post-treatment risk profile using the peri-implantitis risk diagram
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Hypogonadism
A Preliminary Clinical Study to Evaluate Fispemifene in the Treatment of Hypogonadism
The purpose of this study is to determine whether one or more fispemifene dose regimens are more effective than placebo in the treatment of hypogonadism in older men.
- Trial name
- NCT00290134
- Testing
- Fispemifene once daily for 4 weeks
- Where
- 16 sites in United States
- Volunteers
- 100 people
- Sponsor
- QuatRx Pharmaceuticals Company
Prostate Cancer
Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA
This Phase I/II open-label trial aims to evaluate the safety and efficacy of the herbal supplement INM176 in patients with a history of prostate cancer or low-risk disease under active surveillance.
- Trial name
- NCT06600698
- Testing
- INM176
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Milton S. Hershey Medical Center
Edentulous Jaw
Trueness of Intra-Oral Scanners Compared to an Extra-Oral Scanner for Scanning of Mandibular Edentulous Impressions
the relative accuracy of different intraoral scanner types specifically for capturing the complex morphology of edentulous arches, including peripheral borders and mobile tissues, remains an area of investigation, with…
- Trial name
- NCT07740798
- Testing
- Digital impression of the mandibular edentulous arch
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Covid19
Effect of Hypertonic Saturated Saline Mouth Rinse on Covid-19 Virus in Vivo.
Sars-Cov2 virus is transmitted through the respiratory route and by direct contact with contaminated surfaces and subsequent contact with nasal, oral or ocular mucosa.
- Trial name
- NCT04842721
- Testing
- Hypertonic Saturated Saline Mouth Rinse Active Arm
- Where
- Canada
- Sponsor
- Rafik Batroussy
Gingivitis, Dental Plaque
Next Science Antimicrobial Mouth Rinse Study
To assess the effect of a test antimicrobial oral rinse from Next Science on the prevention of oral biofilm formation and thereby preventing gingivitis by monitoring the oral microbial flora and measuring gingival inflammation…
- Trial name
- NCT03154021
- Testing
- Next Science OTC Oral Rinse with Essential Oils, OTC Oral Rinse Control
- Where
- 2 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Florida
Periodontitis, Dental Plaque
Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis
This study compares the effectiveness of powered and manual toothbrushes in reducing gum bleeding and dental plaque in people with stage 3 or 4 periodontitis.
- Conditions
- Periodontitis, Dental Plaque, Gingival Bleeding
- Trial name
- NCT06980714
- Testing
- Powered, Manual
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
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