Clinical trials: Mouth Disease
Oral Health, Old Age; Dementia
Evaluation of the Use of a Novel Oral Health Screening Instrument by Caregivers in Nursing Homes
BACKGROUND: Oral health of nursing home residents is often poor. Oral health is related to general health, quality of life and well-being.
- Conditions
- Oral Health, Old Age; Dementia, Long-Term Care, Nursing Homes
- Trial name
- OHS-interRAI (NCT06536322)
- Testing
- OHS-interRAI
- Where
- Belgium
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Tooth Diseases, Oral Disease
Turkish Version of Child-Friendly Oral Health Questionnaire
Oral problems are a common occurrence among school-age children. In order to develop effective oral health interventions and services, it is essential to determine children's oral health behaviours using an internationally…
- Trial name
- NCT06525090
- Testing
- no intervention-child-administered questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Sleep Bruxism, Adult, Stress
The Effect of Stress, Anxiety, and Depression Experienced by Pregnant Women on Sleep Bruxism and Oral Health
Background The oral health of pregnant women affects not only the systemic health of the mother but also the birth outcome of the fetus.
- Conditions
- Sleep Bruxism, Adult, Stress, Depression, Anxiety
- Trial name
- NCT06520241
- Testing
- Pregnant
- Where
- Turkey (Türkiye)
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Trakya University
Laryngeal Disease, Pharyngeal Diseases
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.
- Conditions
- Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease
- Trial name
- NCT06507202
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Oral Health, Oral Disease
Levilactobacillus Brevis Oral Health
This RCT investigates the impact of an oral supplement containing the probiotic Levilactobacillus brevis CNCM I-5566 on various salivary indicators of oral health.
- Trial name
- LBOH-RCT (NCT06457724)
- Testing
- Levilactobacillus brevis CNCM I-5566
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Oral Leukoplakia, Oral Cancer
Saliva and Plasma Exosomes for Oral Leukoplakia Malignant Transformation Diagnosis and Oral Cancer Prognosis Monitoring
The goal of this observational study is to test the expression levels of salivary and plasma exosomal miR-185 in patients with oral leukoplakia and oral squamous cell carcinoma.
- Trial name
- NCT06469892
- Testing
- Detect the expression level of miR-185 in salivary and plasma exosomes.
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Beijing Stomatological Hospital, Capital Medical University
Oral Disease
Can a Low-threshold Check-up Motivate Older People to Schedule a Dental Visit?
There is little research on the effect of oral screening campaigns for improving oral health in older people. Therefore, the aim of this study is to investigate the effect of a low-threshold contact with an oral health…
- Trial name
- NCT06341959
- Testing
- Oral screening
- Where
- Belgium
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hand, Foot, and Mouth Disease
Hand, Foot, and Mouth Disease: Could EPs®7630 be a Treatment Option
This randomized controlled study aims to evaluate the effectiveness and safety of the pharmaceutical extract EPs® 7630 from P.sidoides in treating hand, foot, and mouth disease in children.
- Trial name
- NCT06353477
- Testing
- EPs® 7630
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Eskisehir Osmangazi University
Melanoma, Non-small Cell Lung Cancer
A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies
This is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and to further evaluate its tolerability and efficacy…
- Conditions
- Melanoma, Non-small Cell Lung Cancer, Breast Cancer, Gastric Cancer
- Trial name
- NCT03329950
- Testing
- CDX-1140, CDX-301, pembrolizumab
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- Celldex Therapeutics
Oral Disease, Stroke, Ischemic
Oral Health in Patients Hospitalized Because of Ischemic Stroke
Maintaining good oral health is essential for general health and quality of life. Results of many anal-yses showed that stroke patients had poorer oral condition and worse periodontal status than control population.
- Trial name
- NCT06332846
- Testing
- oral examination
- Where
- Poland
- Volunteers
- 118 people
- Sponsor
- Pomeranian Medical University Szczecin
HIV, Dental Caries
An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.
The aim of this 2- arm randomized-control study is to determine the effect of an oral hygiene self care intervention on the oral health status and oral health-related quality of life (OHRQoL) of HIV-positive children (age: 8-16…
- Conditions
- HIV, Dental Caries, Quality of Life, Oral Disease
- Trial name
- NCT05540171
- Testing
- Oral health education and instructions/training for self-oral care
- Where
- Nigeria
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Aminu Kano Teaching Hospital
Hand, Foot and Mouth Disease, Herpangina
Surveillance of HFMD in Pediatric Outpatients
The aims of this prospective multicentric study is to determine the types of enteroviruses (EVs) responsible for hand, foot and mouth disease (HFMD) or herpangina in children seen within an ambulatory setting : to detect an…
- Conditions
- Hand, Foot and Mouth Disease, Herpangina, Enterovirus Infections
- Trial name
- PMB (NCT06263439)
- Testing
- Throat/buccal swab sample
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hand, Foot and Mouth Disease
Active Case Finding of Clinical Hand Foot Mouth Disease in Children Aged 6 Months Old to 18 Years Old in Indonesia
An observational study of active case surveillance to identify the pathogens of clinically diagnosed HFMD cases aged 6 months to 18 years old recruited from puskesmas and hospitals in Indonesia.
- Trial name
- NCT06251219
- Testing
- PCR
- Volunteers
- 100 people
- Sponsor
- Sinovac Biotech Co., Ltd
Dry Mouth, Salivary Gland Diseases
Efficacy of Manuka Honey Oral Rinse in Treatment of Xerostomia
Xerostomia causes many clinical problems, including oral infections, speech difficulties, and impaired chewing and swallowing of food thus may affect the individual's quality of life, therefore this study aimed to evaluate the…
- Trial name
- NCT06240806
- Testing
- Manuka Honey, Saline mouthwash
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- British University In Egypt
Gingival Recession, Surgery
Analysis of Root Coverage Stability.
One-hundred and one healthy participants (221 gingival recessions-GRs) were treated from 1987 to 1996. The probing depth (PD), keratinized tissue width (KTW), gingival recession depth (RD), gingival recession width (RW), gingival…
- Conditions
- Gingival Recession, Surgery, Oral Disease
- Trial name
- NCT05439382
- Testing
- Gingival recession regenerative surgery
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Hand, Foot and Mouth Disease
Immunogenicity of the Inactivated EV71 Vaccine Combined With Hepatitis B and Group A Meningococcal Vaccine
The main purpose of this study is to evaluate the immunogenicity and safety of inactivated enterovirus type 71 vaccine combined with recombinant hepatitis B vaccine or Group a meningococcal polysaccharide vaccine.
- Trial name
- NCT06209398
- Testing
- Enterovirus Type 71 Vaccine, inactivated ( Human Diploid Cell ), Recombinant Hepatitis B Vaccine, Group A meningococcal polysaccharide vaccine
- Where
- China
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Hand, Foot and Mouth Disease
Lot-to-lot Consistency Study of Three Commercial Batches of Enterovirus 71 Vaccine
This study is a randomized, blinded study to evaluate the lot-to-lot consistency of immunogenicity, safety, and immune persistence of three consecutive manufacturing lots of EV71 vaccine, in 1500 children aged 6-35 months.
- Trial name
- NCT06146088
- Testing
- EV71 Vaccine
- Where
- 4 sites in China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Oral Disease, Food Selection
Oral Health-related Patterns of Food Selectivity in Dental Populations
The present study was undertaken in order to describe the clinical profiles of food selective behavior in 35-65 years dental and non-dental populations.
- Trial name
- NCT06140654
- Testing
- Clinical oral examination, Food behavior
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Hôpital Rothschild
Hand, Foot and Mouth Disease
A Serosurvey Study of Hand, Foot, and Mouth Disease in Indonesia
This study is a sero-survey study of infants aged 6 months to 71 months in Bandung City and West Bandung District. As initial data to find out how many children have been exposed to human enterovirus type 71 (HEV-71) which causes…
- Trial name
- NCT05637229
- Where
- 2 sites in Indonesia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Hand, Foot and Mouth Disease
A Safety Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Adults, Children and Infants
Enterovirus 71 (EV71), a major pathogen that is responsible for causing hand-foot-and-mouth disease (HFMD) worldwide, is a member of the Human Enterovirus species A, family Picornaviridae.
- Trial name
- NCT01391494
- Testing
- 160Eu/0.5ml in adults, 320Eu/0.5ml in adults, 640Eu/0.5ml in adults
- Where
- China
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences