Clinical trials: Mouth Disease
Oral Disease, Muco-Cutaneo-Ocular Syndrome
Prevalence of Oral Mucosal Alterations in Mucocutaneous Ocular Disorders
The patients will be selected from the pool of the Clinics (Rheumatology, Ophthalmology and Dermatology) of Faculty of Medicine and (Diagnostic center and Oral Medicine) of Faculty of Dentistry -Cairo University.
- Trial name
- NCT03679988
- Volunteers
- 380 people
- Sponsor
- Sherin Alaa Eldin Eisa Elsayed
Periodontal Diseases
Analysis of Gingival Crevicular Fluid
The purpose of this study was to investigate and compare GCF interleukin-1β (IL-1β), interleukin-10 (IL-10), interleukin-36γ (IL-36γ) levels in patients with healthy (H), gingivitis (G) and chronic periodontitis (CP) status.
- Trial name
- GCF (NCT05325905)
- Testing
- Gingival crevicular fluid sampling
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Diabetes Mellitus, Type 2
Efficacy, Safety, and Tolerability of Once Daily Oral Administration of AZD5004 Versus Placebo for 26 Weeks in Adults With Type 2 Diabetes Mellitus.
This is a Phase IIb, randomised, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy, safety and tolerability of AZD5004 in adults with type 2 diabetes mellitus, compared to placebo and active…
- Trial name
- SOLSTICE (NCT06579105)
- Testing
- AZD5004, Semaglutide
- Where
- 97 sites in United States, Canada and 7 more
- Volunteers
- 406 people
- Sponsor
- AstraZeneca
Vitamin D Deficiency
The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile
Participants in this study will be randomized to receive either oral vitamin D pills OR ultraviolet light treatment. The investigators will compare how these two methods of raising vitamin D levels will affect cholesterol levels.
- Trial name
- NCT01688102
- Testing
- Oral Vitamin D3, Ultraviolet Light
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Dental Plaque
Effects of Fixed and Removable Space Maintainers on Periodontal Health and DMFT/Dft Values
Space maintainers are appliances that applied when primary teeth were lost prematurely because of many reasons such as tooth decay, trauma, lack of germ of permanent tooth.4 Space problems play an important role in practice of…
- Trial name
- NCT03608345
- Testing
- space maintainer
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Xerostomia, Dry Mouth
Xerostomia in Patients With a Life-limiting Condition or Frailty
Xerostomia, the subjective feeling of dry mouth, is a common symptom during the last year of life in patients with a life-limiting condition or frailty.
- Trial name
- NCT05506137
- Testing
- Pilocarpine
- Volunteers
- 120 people
- Sponsor
- Maastricht University Medical Center
Fibromyalgia
Effectiveness of Oral Magnesium Supplementation in Fibromyalgia Patients Not Responding to Standard Treatment
Fibromyalgia is a complex widespread pain disorder. OBJECTIVES To evaluate the effectiveness of oral magnesium supplementation in reducing symptom severity among fibromyalgia patients who have not responded to standard treatment…
- Trial name
- NCT07585045
- Testing
- Magnesium glycinate, Vitamins
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Shaikh Zayed Hospital, Lahore
Gingival Enlargement, Gingival Recession
Development and Validation of the Periodontal Aesthetic Perception Scale in Patients With Periodontal Problems
Aesthetics for individuals become increasingly important, while the aesthetic effects of periodontal disease is an important issue that should be assessed by the patient's perception.
- Trial name
- NCT03436537
- Testing
- Periodontal Aesthetic Perception Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Mouth Sores
Post-marketing Study for the Evaluation of Profilm Mouth Sores
The study aims to assess the effect of Profilm Mouth Sores treatment for relieving symptoms caused by mouth sores. It will involve 35 participants and last around 14 days or until the sores heal, with three daily applications.
- Trial name
- NCT06741280
- Testing
- Profilm Mouth Sores
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- i+Med S.Coop.
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Compare the Difference in Occlusal Force Distribution and Denture Retention Using 2 Different Denture Base Materials in Implant Retained Overdenture
The global increase in the aging population has led to a rise in total edentulism, which remains a major public health concern. two-implant-retained mandibular overdentures have been regarded as the standard of care, offering…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07250503
- Testing
- Conventional acrylic resin denture, Flexible resin denture
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gingivitis
Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters
This study aimed to evaluate the effects of 0.2% HA-impregnated dental flosses on the clinical periodontal parameters of patients with gingivitis.
- Trial name
- NCT06307041
- Testing
- Dental floss+Gengigel, Dental Floss
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Özlem SARAÇ ATAGÜN
Healthy, Asthma
A Study in Healthy Subjects and Mild Asthmatics to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways
A study in healthy subjects and mild asthmatics to investigate Pharmacokinetics of AZD5423 when administered in different ways.
- Trial name
- NCT01310322
- Testing
- AZD5423
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Retinopathy of Prematurity
Oral Propranolol for Prevention of Threshold Retinopathy of Prematurity
Extremely premature infants are at risk of developing a potentially blinding eye disease, called retinopathy of prematurity (ROP).
- Trial name
- RoProp (NCT03083431)
- Testing
- Propranolol
- Where
- 3 sites in Germany, Switzerland and 1 more
- Volunteers
- 276 people
- Sponsor
- University of Zurich
Periodontal Diseases, Oral Health Literacy
Oral Health Literacy and Periodontal Status Among Turkish Adults
This observational cross-sectional study aimed to investigate the association between oral health literacy (OHL) and periodontal status among adult individuals attending Biruni University Faculty of Dentistry, Istanbul, Türkiye.
- Conditions
- Periodontal Diseases, Oral Health Literacy, Periodontitis, Health Behaviour
- Trial name
- NCT07341945
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Biruni University
Acromegaly
Oral Glucose Tolerance Testing (OGTT) on Patients Taking Somatostatin Analogs
The purpose of this study is to test the effect of long-acting somatostatin analog medications, taken by patients with acromegaly or carcinoid syndrome, on growth hormone in comparison to healthy controls who are not receiving…
- Trial name
- NCT01371045
- Testing
- Oral Glucose Tolerance Test (OGTT)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Periodontitis, Endodontic Inflammation
Endo-perio Lesion's Treatment With Using Diode Laser 940nm
Periodontal marginal and periapical diseases cause a huge destruction of tissues surrounding the tooth with periodontal patients.
- Trial name
- NCT04628845
- Testing
- Endo-perio therapy with laser 940nm, Endo-perio therapy without laser 940nm
- Where
- 3 sites in Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Community Acquired Pneumonia
Comparative Study of NXL103 Versus Comparator in Adults With Community Acquired Pneumonia
The purpose of this study is to compare the efficacy, safety and tolerance of 2 different dose levels of oral NXL103 with oral comparator in the treatment of community acquired pneumonia in adults
- Trial name
- NCT00653172
- Testing
- NXL103, comparator
- Where
- 60 sites in Chile, Croatia and 7 more
- Volunteers
- 302 people
- Sponsor
- Novexel Inc
Sleep Apnea Syndrome
Treatment of Sleep Apnea Syndrome With nCPAP Versus Oral Appliance
This prospective randomized cross over study aims to compare nCPAP with mandibular advancement device for the treatment of sleep apnea syndrome.The effectiveness of nCPAP and oral appliance on apnea-hypopnea index, daytime…
- Trial name
- NCT00152672
- Testing
- nCPAP vs oral appliance
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Periodontitis, Type 2 Diabetes
Salivary C1P and PGE2 Levels in Periodontitis Patients With T2DM and Effect of Non-Surgical Periodontal Treatment
Diabetes and periodontal disease are the most common chronic multifactorial and inflammatory diseases in humans, and there is a bidirectional relationship between type 2 diabetes and periodontitis.
- Trial name
- NCT05454059
- Testing
- Non-surgical periodontal treatment, ELISA Test, Periodontal Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Cytomegalovirus Infections, HIV Infections
A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine
To determine whether there is a pharmacokinetic drug interaction between oral ganciclovir and oral zidovudine (AZT) and between oral ganciclovir and oral didanosine (ddI).
- Trial name
- NCT00002096
- Testing
- Zidovudine, Didanosine, Ganciclovir
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
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