Clinical trials: Mouth Diseases
Obsessive Compulsive Disorder
Efficacy of Agomelatine in Patients With Obsessive-Compulsive Disorder
The study will evaluate the efficacy of agomelatine compared to placebo on the reduction of Obsessive and Compulsive symptoms after 16 weeks of treatment.
- Trial name
- NCT01108393
- Testing
- Agomelatine A
- Where
- Israel
- Volunteers
- 74 people
- Sponsor
- Institut de Recherches Internationales Servier
Alveolar Bone Loss
Clinical Trial on the Safety and Efficacy of Magnesium Doped Calcium Silicate 3d Alveolar Bone Repair Unit for Periodontal Bone Defects
The goal of this clinical trial is to test in height increment of alveolar bone and safety evaluation index. The main question it aims to answer are: The safety and effectiveness of magnesium calcium silicate three-dimensional…
- Trial name
- NCT05743452
- Testing
- GBR with CS@Mg
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Huntington Disease
An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196
The primary objective of this study is to provide biological samples from patients with Huntington's disease to allow characterisation of the pharmacological mechanism of action of SEN0014196.
- Trial name
- PADDINGTON (NCT01485952)
- Testing
- SEN0014196 (Low Dose), SEN0014196 (High Dose)
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Siena Biotech S.p.A.
Parkinson Disease
Safety, Tolerability and Effects of Mannitol in Parkinson's Disease
Parkinson's disease is a progressive neurodegenerative disease that causes disabling motor and cognitive impairments. Currently, no disease-modifying therapy exists for this disease.
- Trial name
- PD-mannitol (NCT03823638)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Periodontal Diseases, Smoking Cessation
Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy
The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease.
- Trial name
- NCT06145685
- Testing
- Minimally invasive non-surgical periodontal therapy, Conventional non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Alveolar Osteitis
Photo Biomodulation Therapy for Alveolar Osteitis Recovery in Oral Contraceptive Users
does laser effect on alveolar osteitis recovery in oral contraceptive users ?
- Trial name
- NCT06865508
- Testing
- Laser therapy, zinc oxide eugenol dressing.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Badr University
Measles, Mumps
A Study of ProQuad™ in Healthy Children in Korea (V221-023)
This study will compare ProQuad™ and concomitant administration of M-M-R™ II and Varivax™ with respect to immunogenicity, safety and tolerability.
- Conditions
- Measles, Mumps, Rubella, Varicella
- Trial name
- NCT00839917
- Testing
- Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (ProQuad™), M-M-R™ II and Varivax™
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Asthma
Expert Statements Concerning the Tapering of Oral Corticosteroids (OCS) for the Treatment of Asthma
The objectives of this study are to use the Delphi method to assemble an expert panel representing innovation in asthma treatment, to collect freely suggested recommendation statements concerning OCS tapering (and sub-topics)…
- Trial name
- NCT03899740
- Testing
- Brainstorming 1, Ranking - Round 1, Ranking - Round 2
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Association Jean Baptiste Desbrest
Peri-Implantitis
Non-surgical Treatment of Peri-implantitis With and Without Erythritol Air-polishing
Erythritol is a natural sugar alcohol (a four-carbon polyol) produced by the reduction of erythrose. It is considered safe as food additive and has many of the functional properties that are important for subgingival debridement.
- Trial name
- NCT04152668
- Testing
- Titanium curette., Ultrasonic, Air-polishing
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Knut N. Leknes
Traumatology, Maxillofacial Trauma
Advanced Magnetic Resonance Imaging for Perioperative Evaluation of Dental, Oral and Maxillofacial Trauma
Dental, oral, and maxillofacial trauma represents a significant public health concern, with most cases resulting from accidents and occurring frequently in young adults.
- Conditions
- Traumatology, Maxillofacial Trauma, Maxillofacial Injuries
- Trial name
- NCT07012850
- Testing
- Magnetic Resonance Imaging
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Harald Essig
Peri-implantitis
Non-Surgical Treatment of Peri-implantitis with Systemic Azithromycin or Placebo
The primary objective of this study is to evaluate the change in probing depth in patients with peri-implantitis, assessing the influence of systemic antibiotic (azithromycin) adjunctive to non-surgical treatment at 12 months.
- Trial name
- NSTP (NCT06715150)
- Testing
- Azithromcyin
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- University of Santiago de Compostela
Edentulous Jaw
An Observational Clinical Study of the T3 Dental Implant System
This will be a prospective, observational study where all implants will be placed in either the maxilla or mandible and loaded immediately (within 48 hours), early (within 6-8 weeks) or delayed (> 8 weeks) with a provisional or…
- Trial name
- Kashmir (NCT05062863)
- Testing
- T3 dental implant system
- Where
- 4 sites in United States, Germany
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- ZimVie
Intense-exuberant Stomach Fire Syndrom, Acute Pericoronitis
Effectiveness and Clinical Mechanism of Huanglian-Jiedu Decoction in Patients With Intense-exuberant Stomach Fire Syndrome
This clinical research focus on evaluating the effectiveness of Huanglian-Jiedu Decoction in patients with intense-exuberant stomach fire syndrome (one of the common TCM syndrome)of acute pericoronitis,minor recurrent aphthous…
- Conditions
- Intense-exuberant Stomach Fire Syndrom, Acute Pericoronitis, Recurrent Aphthous Stomatitis, Recurrent Herpes Simplex Labialis
- Trial name
- NCT03469232
- Testing
- Huanglian-Jiedu Decoction
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- China Academy of Chinese Medical Sciences
Oral Hygiene, Pneumonia, Bacterial
Effectiveness of Oral Management Strategies on Improving Oral Frailty and Oral Bacteria
The aim of this study is to examine the effectiveness of nurse-driven oral management for improvements of oral frailty, and oral bacteria pneumonia patients with oral frailty using a randomized controlled trial (RCT) design.
- Trial name
- NCT05407532
- Testing
- Group with oral management, Group with oral care
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- National Cheng-Kung University Hospital
Periodontal Diseases
Evaluation of PerioMonitor for Detection of Oral Inflammatory Load (OIL) in Human Subjects
The purpose of this multicenter, prospective, single arm Study is to evaluate the efficacy and safety of PerioMonitor as an aid to the presumptive detection of oral inflammation associated with periodontal diseases.
- Trial name
- NCT05153798
- Where
- 3 sites in United States, Canada
- Volunteers
- 117 people
- Sponsor
- Oral Science International Inc.
Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies
Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases
To evaluate the safety of UTAA09 injection in the treatment of relapsed/refractory (R/R) autoimmune disease (AID). To evaluate the pharmacokinetic (PK) profile of UTAA09 injection in patients with R/R AID.
- Conditions
- Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies, Systemic Sclerosis, Sjogren's Syndrome
- Trial name
- NCT06417398
- Testing
- T cell injection targeting CD19 chimeric antigen receptor
- Volunteers
- 10 people
- Sponsor
- PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Myocardial Infarction
Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction
This is a multicenter, randomized, double-blind, active-controlled, dose-titrating phase 2 study to evaluate the safety and efficacy of firibastat administered orally BID (2 daily doses) versus ramipril administered orally BID…
- Trial name
- QUORUM (NCT03715998)
- Testing
- Ramipril, Firibastat
- Where
- 7 sites in France, Germany and 5 more
- Volunteers
- 295 people
- Sponsor
- Quantum Genomics SA
Osteoarthritis
Study Evaluating AGG-523 in Subjects With Osteoarthritis
This study will evaluate the effect of AGG-523 administration on biomarkers related to osteoarthritis. Safety and tolerability of AGG-523 will also be assessed.
- Trial name
- NCT00427687
- Testing
- AGG-523
- Where
- 3 sites in United States
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Allergy, Asthma
Sublingual Cockroach Safety in Adults With Cockroach Allergy & Perennial Allergic Rhinitis With or Without Asthma
Immunotherapy may help reduce symptoms of allergy and asthma. Problems concerning compliance and adverse events with subcutaneous allergen immunotherapy have generated interest in delivering immunotherapy sublingually (under the…
- Trial name
- SCSS (NCT00434421)
- Testing
- Glycerinated German cockroach allergenic extract
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
PRF, Gingival Recession
Clinical Evaluation of Platelet Rich Fibrin Membrane With or Without Hyaluronic Acid Along With Coronally Advanced Flap in the Treatment of Rt1 Gingival Recession
Gingival recession is a common mucogingival deformity that may result in root hypersensitivity, esthetic concern, plaque accumulation, and difficulty in oral hygiene maintenance.
- Conditions
- PRF, Gingival Recession, Hyaluronic Acid
- Trial name
- NCT07662447
- Testing
- root coverage with multilayered PRF, root coverage with multilayered PRF and hyaluronic acid
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.