Clinical trials: Mouthwash
Dental Plaque
Clinical Research Study Efficacy of a Prototype Oral Rinse
Evaluate the efficacy of an oral rinse on dental plaque and gingival inflammation
- Trial name
- Quigley (NCT01021007)
- Testing
- Iodine, water
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Head and Neck Neoplasms, Mucositis
Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer
Oral Mucositis (OM) is a painful and debilitating side effect of many of the drug/radiation regimens used to treat cancer. This study examines the investigational drug brilacidin and its possible application in prevention of oral…
- Trial name
- Brilacidin (NCT02324335)
- Testing
- Brilacidin
- Where
- 16 sites in United States
- Volunteers
- 61 people
- Sponsor
- Innovation Pharmaceuticals, Inc.
Plaque
A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis
Rinse contains an anti-plaque agent that helps prevent the accumulation of dental plaque associated with gingivitis.
- Trial name
- NCT03421145
- Testing
- 3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Dental Health
Oral Tissue Tolerance of a Mouthrinse
This study is 8 weeks long. People participating in this study will be asked to brush their teeth two times a day. Some people will get a mouthwash. People with a mouthwash will rinse two times a day after brushing their teeth.
- Trial name
- NCT01009554
- Testing
- Potassium Oxylate Mouthwash, Sodium Fluoride Dentifrice
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Xerostomia
Clinical Evaluation of Oral Rinse for Xerostomia
Xerostomia causes a difficulty in eating, have irritated oral tissues, and a poor quality of life. The new oral rinse was designed to reduce the symptoms and improve the patient's quality of life.
- Trial name
- NCT04289051
- Testing
- HYDRAL Oral Rinse, BIOTENE® Oral Rinse
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Sunstar Americas
Dental Plaque, Gingivitis
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation…
- Trial name
- NCT06660069
- Testing
- Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste), CPC Mouthwash (Parodontax Active Gum Health Mouthwash), Regular Fluoride Toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- HALEON
Xerostomia
A Clinical Study to Evaluate the Efficacy of Three Dry Mouth Relief Products Versus Water
This study assessed the efficacy of three dry mouth products (including an experimental Oralbalance gel, oral rinse, and moisturizing spray) to relieve the feeling of dry mouth compared to water, in dry mouth population over a…
- Trial name
- NCT03494985
- Testing
- Experimental Oralbalance Moisturizing Gel, Biotene Original Oral Rinse, Biotene Moisturizing Mouth Spray
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Plaque
A Four-Week Study to Measure the Effectiveness of an Experimental Mouthwash Used After Teeth Cleaning
This study will test the idea that using an experimental mouth rinse after each time you brush your teeth will result in a healthier mouth than using the regular mouth rinse.
- Trial name
- NCT01462110
- Testing
- 19416-154-1, W002194-0221P
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Tooth Erosion
Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
An in situ model will be used to evaluate and compare enamel remineralization of bovine enamel specimens.
- Trial name
- NCT01128972
- Testing
- Sodium fluoride, Sodium monoflurophosphate, Sterile water
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.
This will be a single center, eight week, randomized, double blind, three treatment arm, parallel design, stratified (by mean baseline Schiff Sensitivity Score of the two selected test teeth) study in healthy participants.
- Trial name
- NCT02651467
- Testing
- Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0), Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Plaque, Gingivitis
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
The objective of this clinical research study is to assess the efficacy of a commercially available triclosan/copolymer toothpaste compared to a commercially available oral hygiene multi-component regimen encompassing the use of…
- Trial name
- NCT02366689
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US
The objective of this clinical research study is to evaluate clinical efficacy of Colgate Total Toothpaste as compared to Crest Pro-Health Toothpaste and Crest Pro-Health Mouthwash, and Crest Cavity Protection Toothpaste and…
- Trial name
- NCT02360995
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride toothpaste
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this 12-week clinical study is to evaluate the ability of an experimental mouthwash, containing 0.085 percent (%) Cetylpyridinium chloride (CPC) as an adjunct to toothbrushing with a regular fluoride toothpaste, to…
- Trial name
- NCT06933368
- Testing
- Crest Cavity Protection Toothpaste, Experimental Mouthwash
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- HALEON
Dry Mouth
Improvement of Dry Mouth Sufferers After Using an Experimental Dry Mouth Rinse Compared to a Water Control
The objective of this study is to evaluate dry mouth relief in subjects with self-reported feeling of dry mouth after using an experimental mouth rinse or a positive control compared to a water control.
- Trial name
- NCT04189081
- Testing
- dry mouth rinse, Water Control
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dry Mouth
A Pilot Study to Assess Dry Mouth Relief After Using an Experimental Mouth Rinse
The objective of this pilot study is to determine if an experimental mouth rinse and a marketed dry mouth rinse are more effective in relieving dry mouth compared to water.
- Trial name
- NCT04152642
- Testing
- Marketed Dry Mouth Rinse, Water control, Experimental Dry Mouth Rinse
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Oral Mucosal Disorder
3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes
The primary objective of this study is to evaluate the incidence of oral tissue sloughing through self-report by study subjects and by professional dental examinations.
- Trial name
- NCT04601103
- Testing
- No SLS toothpaste, Medium SLS toothpaste, High SLS toothpaste
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Dental Plaque
Evaluating Commercial Anti-Plaque Products and Oral Rinse
Clinical research study to determine the anti-plaque efficacy of commerical dentifrices and an oral rinse.
- Trial name
- NCT01014143
- Testing
- Fluoride, Chlorhexidine digluconate, Fluoride, triclosan
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque, Gingivitis
A Clinical Trial to Test the Effect of Marketed Mouth Rinses on Decreasing Plaque and Gum Inflammation
The reduction of existing plaque and gum inflammation will be evaluated using two marketed mouth rinses along with tooth brushing after 21 days of use compared to a placebo mouth rinse.
- Trial name
- NCT02233998
- Testing
- Mouth Rinse 1, Mouth Rinse 2, Mouth Rinse 3
- Where
- Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Tooth Stain
A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal
The whitening action of an investigative hydrogen peroxide/sodium fluoride containing mouth rinse will be evaluated through stain removal using mean Lobene Stain Index over 14 days compared to a currently marketed hydrogen…
- Trial name
- NCT02151058
- Testing
- Colgate® Regular Cavity Protection, Experimental Mouth Rinse, Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Dental Plaque
Study to Determine the Anti-plaque Efficacy of Commerical Toothpastes and an Oral Rinse
Calibration study to determine the anit-plaque efficacy of commerical toothpastes and an oral rinse
- Trial name
- NCT01024738
- Testing
- Fluoride, Triclosan, fluoride, Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive