Clinical trials: Mouthwash
Radiation Induced Oral Mucositis
Benzydamine vs Supersaturated Calcium Phosphate Oral Rinses for Radiation Induced Oral Mucositis in Head and Neck Cancer Patients.
The goal of this clinical trial is to compare and correlate salivary macrophage migratory inhibitory factor levels with onset and severity of radiation induced mucositis in head and neck cancer patients by using super saturated…
- Trial name
- NCT07748442
- Testing
- Benzydamine hydrochloride mouthrinse, Super saturated calcium phosphate oral rinses
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Periodontitis, Premature Birth of Newborn
Feasibility and Acceptability of Use of Daily Oral Rinse in Pregnant Women in Rural Nepal
In Nepal, investigators are conducting a cohort study to estimate the relationship between signs of periodontal disease in pregnant women and preterm delivery.
- Trial name
- NCT02788786
- Testing
- Chlorhexidine, Cetylpyridinium chloride, Salt and Water
- Where
- Nepal
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Chronic Gingivitis
Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.
Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.
- Trial name
- NCT04767269
- Testing
- Cuminum Cyminum, herbal Mouthwash
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Xerostomia, Dry Mouth
Efficacy of Natural Enzymes Mouthwash: a Randomised Controlled Trial
The goal of this clinical is to assess the efficacy of natural enzymes mouthwash in the treatment of xerostomia (dry mouth). The main questions it aims to answer are: (1) the efficacy of natural enzymes mouthwash in the…
- Trial name
- NCT05640362
- Testing
- Natural enzymes mouthwash, Benzydamine mouthwash
- Where
- Malaysia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Tooth Erosion
Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
An in situ model will be used to evaluate and compare enamel remineralization of bovine enamel specimens.
- Trial name
- NCT01128972
- Testing
- Sodium fluoride, Sodium monoflurophosphate, Sterile water
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Discoloration
A Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up
The aim of this clinical study is to evaluate the efficacy of an experimental mouthwash used with a marketed whitening toothpaste or a marketed regular fluoride toothpaste, compared to a marketed regular fluoride toothpaste…
- Trial name
- NCT07836998
- Testing
- Whitening Toothpaste, Experimental Mouthwash, Regular Fluoride Toothpaste
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- HALEON
Coronavirus Infection
SINUS WASH Pilot Study in Adults Testing Positive for COVID-19
COVID-19 is highly infectious and transmission of the virus is thought to be similar to that of influenza which can be transferred through droplets released when a person coughs, sneezes or talks.
- Trial name
- NCT04393792
- Testing
- Povidone-Iodine, Normal saline
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Head and Neck Neoplasms, Chemoradiotherapy
Evaluation the Effects of Herbal Gargle for Chemoradiotherapy-induced Oral Mucositis of Head & Neck Cancer, a Pilot Study.
The aim of the study is to evaluate the effects of Herbal gargle on chemoradiotherapy-induced stomatitis in head \& neck cancer patients.
- Conditions
- Head and Neck Neoplasms, Chemoradiotherapy, Stomatitis and Ulceration
- Trial name
- NCT05341206
- Testing
- Herbal gargle, Normal saline
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Dental Caries Prevention
Silver Nanoparticle vs Chlorhexidine Mouthwashes for Reducing Streptococcus Mutans and Improving Salivary pH in Children
Dental caries remains one of the most common chronic diseases in children, with Streptococcus mutans playing a major role in its development.
- Trial name
- SMILE (NCT07728409)
- Testing
- Silver nanoparticle mouthwash (10 ppm), Chlorhexidine mouthwash (0.2%)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Assiut University
Dental Plaque, Gingivitis
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
The objective of this clinical research study is to assess the efficacy of a commercially available triclosan/copolymer toothpaste compared to a commercially available oral hygiene multi-component regimen encompassing the use of…
- Trial name
- NCT02366689
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
An Efficacy Study of Chlorhexidine Mouthwashes
The aim of this study is to compare subject gingival health after 6 weeks of twice daily use of a non-alcohol or alcohol containing mouthrinse and brushing compared to brushing only.
- Trial name
- NCT01751178
- Testing
- Chlorhexidine Digluconate Mouthwash with Alcohol, Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- 3 sites in United Kingdom
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Oral Mucositis
A Mouthwash Medicine for the Reduction or Prevention of Mouth Ulceration Caused by Radiotherapy for Head and Neck Cancer
This study is looking at a new medication called NG11-2 to see if it can reduce a side effect called severe Radiation-induced Oral Mucositis (RIOM) that can happen to people getting radiation treatment for head and neck cancer.
- Trial name
- NCT06669390
- Testing
- NG11-2
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- VasoDynamics Ltd
Plaque, Gum Disease
A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems
This 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the Meridol Base Mouthwash containing 0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride as compared to a…
- Trial name
- NCT05821712
- Testing
- 0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride Mouthwash, 0.057% sodium fluoride Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Postoperative Pain, Tonsillectomy
Ketamine Gargle for Pain After Pediatric Tonsillectomy
Post-tonsillectomy pain in children is a common and clinically significant problem that may lead to poor oral intake, dehydration, and delayed recovery.
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- KET-TONSIL (NCT07558044)
- Testing
- Ketamine Hydrochloride in saline, Normal Saline (0.9% NaCl)
- Where
- Venezuela
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Plaque Induced Gingivitis
Compare the Effect of Green Tea Mouthwash vs Chlorohexidine Mouthwash in Children With Plaque-induced Gingivitis
This study aims to assess and compare the effect of green tea mouthwash compared to chlorohexidine mouthwash in reducing gingivitis and plaque scores (in terms of plaque index and gingival index) in children with plaque-induced…
- Trial name
- NCT05803590
- Testing
- Green tea mouthwash, Chlorhexidine mouthwash
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inhibition of Plaque Formation (by Gingivitis-Index ≤1.5)
Study to Assess the Inhibition of Plaque Formation in Subjects With a Gingival Index ≤1.5
The objective of the study is to demonstrate the superiority of 0.1% octenidine mouthwash (Octenidin Mundspüllösung, OML) to placebo (PLAC) in the inhibition of plaque formation.
- Trial name
- NCT03322124
- Testing
- Octenidinedihydrochlorid
- Where
- 3 sites in Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Schülke & Mayr GmbH
Halitosis
Effect of a Mouthwash Containing Chlorhexidine and Chlorine Dioxide on Halitosis
Halitosis significantly impacts the quality of a patient's life. This randomized, double-blind crossover trial evaluates a mouthwash containing chlorhexidine (0.01%) and chlorine dioxide (0.05%) compared with placebo.
- Trial name
- CHX+CDO (NCT07265102)
- Testing
- CHX 0.01% + CDO 0.05% mouthwash
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Gingivitis
Effectiveness of Propolis Mouthwash on Gingivitis
Mouthrinses have been in used for centuries as breath fresheners, medicaments, and antiseptics. Recently, propolis has caught the eyes of dentists worldwide and researches are being carried out to infuse the usage of propolis in…
- Trial name
- NCT04032548
- Testing
- Propolis mouthwash, Chlorhexidine mouthwash
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mahsa University
Advanced Breast Cancer
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
Open-label, Phase II study of Stomatitis prevention with a steroid-based mouthwash in Post-menopausal women with ER+, HER2- Metastatic or Locally Advanced Breast Cancer
- Trial name
- NCT02069093
- Testing
- Dexamethasone based mouthwash, Everolimus, Exemestane
- Where
- 23 sites in United States
- Volunteers
- 92 people
- Sponsor
- Novartis Pharmaceuticals
Radiation-Induced Xerostomia
Comparative Analysis of BioXtra on Xerostomia
The present study compared the efficacy of BioXtra spray and mouth rinse in the relief of radiotherapy-induced xerostomia in patients referred to Cancer Institute, Tehran Imam Khomeini Hospital.
- Trial name
- BioXtra (NCT01195233)
- Testing
- bioxtra
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Qazvin University Of Medical Sciences