Clinical trials: Mouthwashes
Gingivitis, Dental Plaque
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction.
- Trial name
- NCT04723732
- Testing
- Myrrh mouthwash, Chlorhexidine mouthwash, Normal saline
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Periodontal Diseases
Anti Plaque Efficacy of Salvadora Persica L. and Green Tea Mouthwash
Periodontal diseases and caries are essentially initiated and progressed by accumulation of dental plaque. Thus, daily effective plaque control is valuable as a preventive measure and maintaining oral health.
- Trial name
- NCT03790904
- Testing
- Co., Kin, Distilled water
- Where
- Iraq
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Healthy, Dental Plaque
Short-Term Anti-plaque Effect of Cymenol Mouthwash Analysed Using Dentius Deep Plaque Software
The objective of this project was to investigate the short-term in situ anti-plaque effect of cymenol, using the Dentius Deep Plaque software
- Trial name
- NCT05521230
- Testing
- Cymenol mouthwash
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Periodontal Diseases
A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases
Aim: clinical effectiveness of 0.05% cetylpyridinium chloride mouth rinse in patients with gingivitis as compared to non-alcoholic chlorhexidine mouth wash.
- Trial name
- NCT02756377
- Testing
- cetylpyridinium chloride mouthwash, Chlorhexidine mouthwash
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Mouthwashes, Chlorhexidine
Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining
Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with…
- Conditions
- Mouthwashes, Chlorhexidine, Dental Plaque, Gingival and Periodontal Disease
- Trial name
- NCT07351370
- Testing
- chlorhexidine/ cetylpyridinium chloride/ hydrogen peroxide mouthwash, Chlorhexidine/ cetylpyridinium chloride
- Where
- Greece
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Dental School
Dental Health
Oral Tissue Tolerance of a Mouthrinse
This study is 8 weeks long. People participating in this study will be asked to brush their teeth two times a day. Some people will get a mouthwash. People with a mouthwash will rinse two times a day after brushing their teeth.
- Trial name
- NCT01009554
- Testing
- Potassium Oxylate Mouthwash, Sodium Fluoride Dentifrice
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Generalized Gingivitis
The Effect of SOW Mouthwash on the Level of IL_1β in GCF and Some Clinical Periodontal Parameters for Patients With Gingivitis
Forty-five adult male patients with generalized gingivitis participated in the double blinded randomized controlled parallel study divided into three groups, two mouth rinses and distilled water( negative control) used during…
- Trial name
- NCT04328753
- Testing
- Super Oxide water, Chlorhexidine mouthwash, Distilled water
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontitis, Dental Plaque
Antiplaque/Antigingivitis Effect of Lacer Oros Integral
Background; A new mouth rinse formulation ("Lacer Oros Acción Integral", Lacer SA, Barcelona, Spain) has been recently proposed, including O-Cymen-5-ol, potassium nitrate, zinc chloride, dipotassium glycyrrhizate, sodium…
- Conditions
- Periodontitis, Dental Plaque, Gingival Inflammation
- Trial name
- LacerINT (NCT04881357)
- Testing
- test mouth rinse (Lacer Oros Acción Integral - new formula, Barcelona, Spain)., control group
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Oral Biofilm, Dental Plaque
Essential Oils With and Without Alcohol: Substantivity and Antiplaque Effect
The Essential oils (EO) are composed by a wide diversity of products. Therefore, their antimicrobial activity will be related to their composition, configuration, amount and their possible interaction.
- Conditions
- Oral Biofilm, Dental Plaque, Periodontitis
- Trial name
- NCT03146390
- Testing
- Essential oils, Alcohol free essential oils, Water
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Xerostomia, Dry Mouth
Efficacy of Natural Enzymes Mouthwash: a Randomised Controlled Trial
The goal of this clinical is to assess the efficacy of natural enzymes mouthwash in the treatment of xerostomia (dry mouth). The main questions it aims to answer are: (1) the efficacy of natural enzymes mouthwash in the…
- Trial name
- NCT05640362
- Testing
- Natural enzymes mouthwash, Benzydamine mouthwash
- Where
- Malaysia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Postoperative Complications
The Effect of Peppermint Flavored Mouthwash Applied to Patients
Treatment of obesity consists of diet/lifestyle modification and bariatric surgery consisting of several procedures. One of the most common complications in the early period after bariatric surgery is nausea and vomiting due to…
- Trial name
- NCT05990140
- Testing
- peppermint flavored mouthwash
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Gingival Inflammation
Safety and Preliminary Efficacy of Lipoxin Analog BLXA4-ME Oral Rinse for the Treatment of Gingivitis
The primary objective is to evaluate the safety of an investigational compound, BLXA4-ME, topically applied as a daily oral rinse in adults with gingivitis.
- Trial name
- BLXA4 (NCT02342691)
- Testing
- BLXA4
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- The Forsyth Institute
Gingivitis
Dose Finding Study to Assess Octenidine Mouthwash Concentrations in Comparison to Placebo
The objective of this clinical trial is to identify the most efficacious octenidine dihydrochloride concentration regarding bacterial count reduction in comparison to a placebo in the oral cavity.
- Trial name
- OML0113 (NCT02138552)
- Testing
- Octenidine dihydrochloride
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Schülke & Mayr GmbH
Molar Incisor Hypomineralization
Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH. In Vitro Study and In Situ Randomized Double-Blind Placebo Clinical Trial.
In child patients with molar incisor hypo mineralization, Will Vitamin D mouth wash offer more success for patients with MIH as regards better MIH TNI index, decrease plaque accumulation, more gingival health and less bleeding on…
- Trial name
- NCT06515548
- Testing
- Vitamin D3 mouth wash
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Recurrent Aphthous Stomatitis
Topical Hyaluronic Acid and Recurrent Aphthous Stomatitis.
This study was conducted to estimate the hypothesis that the topical hyaluronic acid mouthwash have no role in the treatment of recurrent aphthous stomatitis
- Trial name
- NCT04265001
- Testing
- Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
COVID-19
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19
The SARS-CoV-2 coronavirus pandemic is responsible for more than 180,000 deaths worldwide and 20,000 deaths in France. To date, no treatment or vaccine has been successful.
- Trial name
- KILLER (NCT04371965)
- Testing
- Povidone-Iodine
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Poitiers University Hospital
Gingivitis
A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease
Participants will be given special instructions about taking care of their teeth during the 18 hours before they come to the dentist's office for screening/baseline, 1 week, 2 weeks and 4 weeks.
- Trial name
- NCT02065414
- Testing
- Listerine Advance Gum Defense, Mouth rinse containing Chlorhexidine, Mouth rinse containing 5% Hydroalcohol
- Where
- United Kingdom
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingival Diseases
Effects of Three Different Mouth Rinses on Dental Plaque in Children
Dental plaque is a major problem in the field of oral and dental health and its prevention is more important to avoid dental caries and gingival diseases.
- Trial name
- NCT06013735
- Testing
- sodium fluoride solution, guava leaves aqueous extract, pomegranate peel aqueous extrac
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Periodontitis
Evaluating the Efficacy of Resveratrol Containing Mouthwash as Adjunct Treatment Periodontitis:
To evaluate the effectiveness of resveratrol mouthwash as adjunct to NSP treatment of periodontitis
- Trial name
- resveratrol (NCT05874882)
- Testing
- resveratrol mouthwash as adjunct to scaling and root planing in periodontitis patients, chlorhexidine mouthwash as adjunct to scaling and root planing in periodontitis patients
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Wound Heal, Surgical Wound
Chlorhexidine Plus Hyaluronic Acid Mouthwash in Surgical Wound Healing Following Third Molar Surgery
Evaluation of the response of gingival tissues to the use of mouthwash with chlorhexidine and chlorhexidine + hyaluronic acid in terms of healing of the surgical wound following third molar surgery.
- Conditions
- Wound Heal, Surgical Wound, Impacted Third Molar Tooth
- Trial name
- CLOR_4 (NCT05414253)
- Testing
- Parallel Assignment
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pisa