Clinical trials: Mouthwashes
Healthy Subjects
Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth
A clinical study to evaluate the effect of a commercial mouth rinse on plaque re-growth
- Trial name
- NCT01122862
- Testing
- 0.12% chlorhexidine mouthrinse, Cosmetic mouthrinse, Sterile water
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontal Diseases
Compare the Efficacy of Aloe Vera Mouthwash With Non- Alcoholic Chlorhexidine Mouthwash on Periodontal Diseases
Aim: To compare the efficacy of Aloe Vera and non-alcoholic chlorhexidine mouthwash in the treatment of Periodontal diseases. Methods \&Material: 32 patients were selected, the following periodontal parameters were recorded at…
- Trial name
- NCT02560870
- Testing
- Active Comparator:Aloe Vera mouthwash, Active Comparator:Chlorhexidine mouthwash
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Gingivitis, Periodontitis
OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study.
Periodontal disease- Inflammatory, Multifactorial, and Threshold disease. Periodontal disease is a highly prevalent dental disease, an almost 100% prevalence in developing countries.
- Conditions
- Gingivitis, Periodontitis, Aerosol Disease, Gingival Disease
- Trial name
- NCT03839719
- Testing
- Group PI, Group OC, Group CHX
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Group A Streptococcus: B Hemolytic Pharyngitis
Detection of GABHS in Throat Gargle
The objective of this study is to investigate the use of patient throat gargle as an alternative to throat swabbing for the diagnosis of pharyngitis caused by Group A β-Hemolytic Streptococcus (GABHS) infection, also known as…
- Trial name
- NCT03231098
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Gargle Tech
Recurrent Aphthous Stomatitis
Clinical Evaluation of Fluid Extract of Chamomilla Tincture for Oral Aphthae
Recurrent aphthous stomatitis is a difficult to treat and quite common chronic inflammatory disease of the oral mucosa. This study evaluates the fluid extract from Chamomilla recutita's safety and effectiveness in treatment of…
- Trial name
- NCT01122147
- Testing
- chamomilla tincture mouthwash
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Mashhad University of Medical Sciences
Leukoplakia, Periodontal Disease
Randomized, Double Blind, Placebo-Controlled, Phase IIB Trial of Ketorolac Mouth Rinse Evaluating the Effect of Cyclooxygenase Inhibition on Oropharyngeal Leukoplakia: Collaborative Study of the NCI, NIDCD and the NIDCR
In Phase II trials, treatment with ketorolac tromethamine oral rinse has been shown to block periodontal disease progression even in the absence of standard clinical intervention such as scaling and root planing which is…
- Trial name
- NCT00001698
- Testing
- Ketorolac Rinse
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- National Cancer Institute (NCI)
Peri-implant Mucositis
Domiciliary Use of Hyaluronic Acid Gel Solutions vs Domiciliary Use of Chlorhexidine Mouthwash 0,20% for the Management of Peri-implant Mucositis Sites
This is a randomized controlled clinical trial (RCT). After signing the informed consent, patients satisfying the inclusion criteria will undergo supragingival and subgingival professional oral hygiene of both arches performed…
- Trial name
- NCT05312593
- Testing
- Aftoral Oral Gel, Unidea Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Pavia
Esophageal Adenocarcinoma, Barrett's Esophagus
Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome
This is a randomized, open-label pilot study to assess whether treatment with chlorhexidine mouthwash can alter the esophageal and gastric cardia microbiome
- Conditions
- Esophageal Adenocarcinoma, Barrett's Esophagus, Reflux Esophagitis
- Trial name
- Mouthwash (NCT02513784)
- Testing
- Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Columbia University
Oral Mucositis
A Mouthwash Medicine for the Reduction or Prevention of Mouth Ulceration Caused by Radiotherapy for Head and Neck Cancer
This study is looking at a new medication called NG11-2 to see if it can reduce a side effect called severe Radiation-induced Oral Mucositis (RIOM) that can happen to people getting radiation treatment for head and neck cancer.
- Trial name
- NCT06669390
- Testing
- NG11-2
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- VasoDynamics Ltd
Oral Mucositis (Ulcerative) Due to Radiation
Dexpanthenol Mouthwash to Treat Oral Mucositis
Oral mucositis can be a significant problem for cancer patients. It is typically associated with pain and increased risk of infection and can lead to impaired nutritional status and inadequate hydration.it can be seen in the…
- Trial name
- NCT01318889
- Testing
- Dexpanthenol
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Sore Throat
Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore Throat
Post-operative sore throat (POST) following General Anesthesia with endotracheal is a common symptom and drains resources. The researchers will compare preoperative gargling of Asprine and Benzydamine HCL to study comparative…
- Trial name
- Postbenas (NCT05343429)
- Testing
- Benzydamine hydrochloride, Aspirin
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Denture Stomatitis
Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis
The aim of the present study was to compare the effect of aqueous extract of garlic with nystatin mouthwash in denture stomatitis.
- Trial name
- NCT01198223
- Testing
- garlic , nystatin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Qazvin University Of Medical Sciences
Healthy
A Twelve Week Study of Prototypes Mouth Rinses
The purpose of this study is to evaluate the safety and efficacy of two essential oil containing experimental mouth rinse formulations and an essential oil containing mouth rinse compared to a hydroalcohol control mouth rinse for…
- Trial name
- NCT05526586
- Testing
- Colgate Cavity Protection Toothpaste, Zero Alcohol Gum Prototype, Alcohol Gum Prototype
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
High Caries Risk Patients, Antimicrobial Effect
Antibacterial Effect of Guava Leaves Extract Mouthwash Compared to Chlorhexidine Mouthwash in High Caries Risk Patients
This trial is to test the antibacterial effect of Guava leaves extract mouth wash compared to Chlorhexidine mouth wash in high caries risk patients. Also salivary pH and patient satisfaction to taste will also be tested.
- Conditions
- High Caries Risk Patients, Antimicrobial Effect, Salivary pH, Patient Satisfaction to Taste
- Trial name
- NCT03773094
- Testing
- Guava leaves extract, Chlorhexidine
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cairo University
Esophageal Cancer, Gastric Cancer
Evaluation of the Preventive Effect of Chlorhexidine Acetate Gargle for Upper Gastrointestinal Tract Infection After ESD
Backgrounds： With the continuous improvement of sterilization and endoscopic structure, the infection caused by endoscopy has gradually declined.With the rapid development of digestive endoscopic therapy in the past decade…
- Trial name
- NCT03492827
- Testing
- chlorhexidine acetate gargle
- Where
- China
- Volunteers
- 306 people
- Sponsor
- Peking University Third Hospital
Xerostomia
Clinical Evaluation of Oral Rinse for Xerostomia
Xerostomia causes a difficulty in eating, have irritated oral tissues, and a poor quality of life. The new oral rinse was designed to reduce the symptoms and improve the patient's quality of life.
- Trial name
- NCT04289051
- Testing
- HYDRAL Oral Rinse, BIOTENE® Oral Rinse
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Sunstar Americas
Oral Health, Menopause
Womens Health Screening and the Oral Microbiome
The overall aims of this project are to undertake a women's health screening clinic on oral health and systemic health, linking the oral microbiome to hormonal status (menopause); The follow quantitative and qualitative markers…
- Conditions
- Oral Health, Menopause, Gum Disease, Mouthwash
- Trial name
- NCT07859761
- Testing
- Listerine mouthrinse
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Dental Caries
Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)
the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.
- Trial name
- NCT05841589
- Testing
- Green tea extract mouth rinse, Garlic with lime extract mouth rinse, Pomegranate extract mouth rinse
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- omnia sayed
Oral Hygiene, Oral Health
Antibacterial Effect of Ozonated Olive Oil, Propolis and Chlorhexidine Mouthwashes in Pediatric Patients
Streptococcus mutans and Lactobacillus acidophilus are the most common cariogenic microorganisms. Chlorhexidine has been the most widely used antibacterial mouthwash in dentistry.
- Trial name
- NCT07197073
- Testing
- Ozonated olive oil, Propolis, Chlorhexidine
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Alexandria University
Cancer of Head and Neck, Mucositis Oral
Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial
Patients with head and neck cancer generally receive a standard of care of 7 weeks of daily radiation therapy given alongside an aggressive chemotherapy drug called cisplatin.
- Conditions
- Cancer of Head and Neck, Mucositis Oral, Pharyngeal Mucositis
- Trial name
- NCT05331131
- Testing
- Ketamine Topical
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health