Clinical trials: Mouthwashes
Covid19
Oral Rinse to Reduced Expelled Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During COVID-19 Infection
Prospective, cross-sectional study evaluating the effect of commercially available mouthwashes on expelled/exhaled SARS-CoV-2 viral load using face mask sampling.
- Trial name
- NCT04931004
- Testing
- Mouthwash Product
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Gingivits in Diabetics
A Study of Mouth Rinses in Type 1 and Type 2 Diabetic Participants
The purpose of this study is to evaluate mouth rinse formulations for oral soft tissue tolerance and efficacy in plaque/ gingivitis prevention/reduction in Type 1 and Type 2 diabetics when used twice daily as an adjunct to tooth…
- Trial name
- NCT04449952
- Testing
- Listerine Cool Mint, 5% Hydroalcohol Mouth Rinse, Colgate Cavity Protection Toothpaste
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Good Health, Gingival Inflammation and Bleeding
Oil Pulling Reduction
The goal of this study is to scientifically evaluate the efficacy of this oil pulling oral rinse in reducing dental plaque, gingival inflammation, gingival bleeding, and selectively reducing caries- and periodontal…
- Conditions
- Good Health, Gingival Inflammation and Bleeding, Dental Plaque
- Trial name
- NCT07706647
- Testing
- GuruNanda natural Oil Pulling oral rinse, TheraBreath Plaque Control Oral Rinse, GuruNanda water-based non-whitening mouthwash
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Covid19
Evaluation of SARS-COV-2 Viral Load of Covid-19 Patients After Rinsing With Oral Antimicrobial Mouthwashes
The aim of this study is to analyze the efficacy of oral disinfection with 0.075% Cetylpyridinium Chloride alone and 0.075% Cetylpyridinium Chloride associated with 0.28% zinc lactate in reduction of the viral load of SARS-CoV-2…
- Trial name
- NCT04902976
- Testing
- CPC+ZN, CPC, Negative Control
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Hospital Israelita Albert Einstein
Gingivitis; Chronic, Oxidative Stress
Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study
Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases.
- Conditions
- Gingivitis; Chronic, Oxidative Stress, Inflammation
- Trial name
- NCT05861206
- Testing
- GT-MW group (5% Green tea), WT-MW group (5% White tea),EO-MW group (Listerine mouthrinse), CHX-MW group (0.12% CHX, as a positive control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yağmur Saraç Gül
Gingivitis, Plaque
Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a positive control mouth rinse and a hydroalcohol control mouth rinse for the reduction of gingivitis and…
- Trial name
- NCT04921371
- Testing
- Colgate® Cavity Protection Toothpaste, Listerine® Cool Mint®, Concept Curve Winter Series Toothbrush
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Malignant Neoplasm, Oral Pain
MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN)
This phase II trial studies how well methylene blue works in treating patients with cancer and pain associated with oral mucositis. Methylene blue may relieve pain associated with oral mucositis.
- Conditions
- Malignant Neoplasm, Oral Pain, Stomatitis
- Trial name
- NCT03469284
- Testing
- Best Practice, Methylene Blue
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- M.D. Anderson Cancer Center
Tooth Discoloration
A Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up
The aim of this clinical study is to evaluate the efficacy of an experimental mouthwash used with a marketed whitening toothpaste or a marketed regular fluoride toothpaste, compared to a marketed regular fluoride toothpaste…
- Trial name
- NCT07836998
- Testing
- Whitening Toothpaste, Experimental Mouthwash, Regular Fluoride Toothpaste
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- HALEON
Periodontitis, Bleeding Gum
Effect of a Hydrogen-Peroxide and Hyaluronic-Acid Mouthwash (BMG0703) in the Treatment of Periodontitis
Assessment of the efficacy of BMG0703 in the treatment of periodontitis and control of supragingival plaque, compared to Chlorhexidine and a placebo product
- Conditions
- Periodontitis, Bleeding Gum, Pocket, Periodontal
- Trial name
- NCT04446533
- Testing
- Hydrogen Peroxide and Hyaluronic acid filming formulation, Chlorhexidine 0.2%
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Tooth Extrusion, Wound Healing
Assessment of the Efficacy and Safety of OROXID® Oral Solution in Patients With Oral Cavity Surgery
Oral tissue healing is significantly affected by the high bacterial load and constant mechanical stress within the oral cavity. To control bacterial colonization and support healing, both topical and systemic treatments-such as…
- Trial name
- OroxSurge (NCT06987253)
- Testing
- OROXID® forte oral solution, Standard of Care (SOC)
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- ENIKAM d.o.o.
COVID-19, Coronavirus Infection
Efficacy of Oral Rinses for Inactivation of COVID-19 (MOR2)
Randomized, double-blind prospective trial to test the efficacy of therapeutic, antiseptic mouth rinses to inactivate severe acute respiratory syndrome coronavirus (SARS-CoV-2) in saliva of COVID-19 positive patients aged 18-65…
- Conditions
- COVID-19, Coronavirus Infection, SARS CoV 2 Infection
- Trial name
- MOR2 (NCT05178173)
- Testing
- 27% Ethanol plus essential oils, 0.075% Cetylpyridinium Chloride
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Caries
Effect of Enzyme-containing Mouth Rinse on Dental Biofilm in Patients With Fixed Orthodontic Appliances
Caries is a biofilm-mediated global public health problem causing health, social and economic consequences for individuals, communities and countries.
- Trial name
- NCT05033015
- Testing
- Mouth rinse
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Malmö University
Dentin Sensitivity
A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity
This study is for people with sensitive teeth and involves going to the dentist for 4 visits over 6 weeks. At each visit the dentist will look at the mouth, teeth, tongue and gums of subjects, and check for sensitive teeth.
- Trial name
- NCT01727258
- Testing
- Mouth Rinse, Fluoride Toothpaste, Potassium Nitrate Toothpaste
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Healthy
A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashes
The purpose of this trial is to evaluate the amount of saliva generated and changes in the oral Potential of Hydrogen (pH) after a single use of essential oil (EO)-containing mouth rinses compared to a negative control.
- Trial name
- NCT06136455
- Testing
- Listerine Clinical Solutions Teeth Strength, Listerine Total Care Zero Alcohol Mouthwash, Listerine Cool Mint Zero Alcohol Mouthwash
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Healthy
A Twelve Week Study of Virtually Supervised Mouth Rinse and Flossing
The purpose of this study is to evaluate the efficacy of brushing, flossing, and rinsing with an alcohol containing essential oil mouth rinse; brushing and flossing; versus brushing and rinsing with an alcohol containing…
- Trial name
- NCT04750005
- Testing
- Listerine Cool Mint, Colgate Cavity Protection Toothpaste, Reach Unflavored Waxed Dental Floss
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Hypertension
Effects of Mouthwashes on the Oral Microbiome and Systemic Health
OVERVIEW While antimicrobial mouthwashes are proven to be clinically effective for management of certain oral microbial diseases, recent studies suggest tha, in addition to targeting bacteria responsible for gum diseases such as…
- Trial name
- NCT07356271
- Testing
- Use of mouthwashes
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Oral Malodor
Controlling Oral Malodor by ClōSYS Oral Rinse
The purpose of this Study is to assess the efficacy of two ClōSYS Oral Rinse products in human subjects in controlling oral malodor in partial fulfillment of the requirements for recognition by the American Dental Association's…
- Trial name
- NCT03160573
- Testing
- ClōSYS® Unflavored Rinse, ClōSYS® Flavored Rinse
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Periodontitis, Premature Birth of Newborn
Feasibility and Acceptability of Use of Daily Oral Rinse in Pregnant Women in Rural Nepal
In Nepal, investigators are conducting a cohort study to estimate the relationship between signs of periodontal disease in pregnant women and preterm delivery.
- Trial name
- NCT02788786
- Testing
- Chlorhexidine, Cetylpyridinium chloride, Salt and Water
- Where
- Nepal
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
COVID-19
COVID-19 Infection Control Using H2O2 Mouth Wash and Nasal Spray
Hydrogen peroxide is produced physiologically by oral bacteria and plays a significant role in the balance of oral microecology since it is an important antimicrobial agent.
- Trial name
- NCT04878042
- Testing
- Hydrogen peroxide
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- EPISTATA
Gingivitis, Plaque Accumulation
Evaluation Study of a Mouthwash Based on Schinus Terebinthifolius to Treat Gingivitis in Children
The purpose of this study is to evaluate the clinical efficacy of a mouthwash based on a natural product (Schinus terebinthifolius) used by children with gingivitis.
- Trial name
- NCT01197105
- Testing
- Use of natural product (Schinus terebinthifolius)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba