Clinical trials: Mouthwashes
Group A Streptococcus: B Hemolytic Pharyngitis
Detection of GABHS in Throat Gargle
The objective of this study is to investigate the use of patient throat gargle as an alternative to throat swabbing for the diagnosis of pharyngitis caused by Group A β-Hemolytic Streptococcus (GABHS) infection, also known as…
- Trial name
- NCT03231098
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Gargle Tech
Advanced Breast Cancer
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
Open-label, Phase II study of Stomatitis prevention with a steroid-based mouthwash in Post-menopausal women with ER+, HER2- Metastatic or Locally Advanced Breast Cancer
- Trial name
- NCT02069093
- Testing
- Dexamethasone based mouthwash, Everolimus, Exemestane
- Where
- 23 sites in United States
- Volunteers
- 92 people
- Sponsor
- Novartis Pharmaceuticals
Gingivitis
Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use
The objective of this six-month clinical research study is to evaluate the clinical efficacy of a new mouthwash on helping prevent gum problems (gingival index scores ) in adults as compared to a control mouthwash.
- Trial name
- NCT06770114
- Testing
- Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash, PhosFlur Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Leprosy, Hansen's Disease
The Effects of Traditional Chinese Medicine Mouthwash Solutions on the Oral Health of Leprosy Patients
The purpose of this study is to treat with traditional Chinese medicine mouthwash, and through the research of dental plaque detection and xerostomia questionnaire and traditional Chinese medicine treatment mechanism.
- Conditions
- Leprosy, Hansen's Disease, Xerostomia, Plaque
- Trial name
- NCT05091216
- Testing
- Traditional Chinese Medicine mouthwash, Dilute 50 times of Traditional Chinese Medicine mouthwash
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Lo-Sheng Sanatorium
Gingivitis
Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children
The mechanical control of supragingival biofilm is accepted as one of the most important measures to prevent dental caries and periodontal diseases. Nevertheless, maintaining dental surfaces biofilm-free is not an easy task.
- Trial name
- NCT02949583
- Testing
- Punica granatum Linn., chlorhexidine
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Universidade Estadual da Paraiba
Elderly, Periodontal Disease
Oral Hygiene Assistance Training Program
This is an oral health study with a nursing home staff training program and product intervention.
- Conditions
- Elderly, Periodontal Disease, Gingivitis, Caries,Dental
- Trial name
- NCT07807397
- Testing
- Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Candidiasis, Oral
Nitric Oxide Releasing Mouthwash (NORM) for the Management of Oropharyngeal Candidiasis
Phase 1 Single Centre, open-labeled Clinical Trial to Evaluate the Safety and Tolerability of Topical Nitric Oxide Releasing Mouthwash (NORM) for the Management of Oropharyngeal Candidiasis.
- Trial name
- NCT06120816
- Testing
- Nitric Oxide
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Sanotize Research and Development corp.
Gingival Inflammation
Safety and Preliminary Efficacy of Lipoxin Analog BLXA4-ME Oral Rinse for the Treatment of Gingivitis
The primary objective is to evaluate the safety of an investigational compound, BLXA4-ME, topically applied as a daily oral rinse in adults with gingivitis.
- Trial name
- BLXA4 (NCT02342691)
- Testing
- BLXA4
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- The Forsyth Institute
Gingivitis
Evaluation of the Effect of the Mouthwash on Delicate Gums
The goal of this study is to learn if a mouthwash works to alleviate gingivitis in adults. It will also learn about the safety of the product.
- Trial name
- NCT07551908
- Testing
- Mouthwash for delicate gums
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Wound Healing Time
Enhanced Early Soft-Tissue Healing With THERAVEX Technology
randomized, double-blind clinical trial aims to evaluate the effect of different postoperative mouthwashes on early soft-tissue healing following tooth extraction
- Trial name
- NCT07580599
- Testing
- THERAVEX Total Oral Care Plus, Chlorhexidine 0.12% (Paroex), Warm saline
- Where
- Lebanon
- Volunteers
- 51 people
- Sponsor
- Biointelligent Technology Systems SL
Molar Incisor Hypomineralization
Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH. In Vitro Study and In Situ Randomized Double-Blind Placebo Clinical Trial.
In child patients with molar incisor hypo mineralization, Will Vitamin D mouth wash offer more success for patients with MIH as regards better MIH TNI index, decrease plaque accumulation, more gingival health and less bleeding on…
- Trial name
- NCT06515548
- Testing
- Vitamin D3 mouth wash
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Iranian Traditional Mouth Rinse Punica Granatum Pleniflora (Golnaar) in Treatment of Gingivitis in Diabetic Patients
This is a triple-blinded randomized clinical trial to evaluate the effect of an Iranian traditional mouth rinse (Punica granatum Pleniflora or "Golnaar" mouthrinse) on treatment of diabetic gingivitis and compare it with…
- Trial name
- Golnaar (NCT02227485)
- Testing
- Punica granatum Pleniflora (Golnaar) mouth rinse, Chlorhexidine (0.2%), Tooth bleaching
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shiraz University of Medical Sciences
Radiation-induced Xerostomia
The Efficacy of Hibiscus Sabdariffa in Xerostomia
The goal of this [ type of study: Clinical trial] is to test effectiveness of Hibiscus Sabdariffa L. mouth rinse using the subjective dry mouth score as a primary objective and to assess the effect of that mix on the salivary…
- Trial name
- NCT06413550
- Testing
- Hibiscus Sabdariffa
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Plaque-Induced Gingivitis, Orthodontic Treatment
Clinical Outcomes of Different Mouth Rinses During Clear Aligner Orthodontic Therapy
This pilot randomized controlled clinical trial will evaluate the feasibility and preliminary clinical effects of three mouth rinses-alum, Triphala-based herbal mouth rinse, and 0.2% chlorhexidine-in adults undergoing clear…
- Trial name
- NCT07865416
- Testing
- Alum Mouth Rinse, Triphala-based Herbal Mouth Rinse, Chlorhexidine mouth rinse
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Manav Rachna International Institute of Research and Studies
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Halitosis
Evaluation of Clinical and Cost-effectiveness of Different Mouthwashes on Controlling Halitosis Among a Group of Egyptian Children
To evaluate the clinical and cost-effectiveness of mouthwash containing Curcuma longa (Turmeric extract) versus mouthwash containing essential oils and Placebo mouthwash on controlling Halitosis among a group of Egyptian children.
- Trial name
- NCT04905940
- Testing
- Turmeric mouthwash
- Volunteers
- 30 people
- Sponsor
- Cairo University
Dentin Sensitivity
A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
This study will investigate the longitudinal efficacy of two experimental oral rinses, one containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX) /0 Parts per Million (ppm fluoride) and the other 2.0% w/w KOX…
- Trial name
- NCT02753075
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Alveolar Osteitis
Efficacy of 0.2 % Digluconate Chlorhexidine Mouthwash for Preventing Alveolar Osteitis After Third Molar Extraction
The purpose of this study is to demonstrate the efficacy of 0.2 % digluconate chlorhexidine mouthwash in the prevention of alveolar osteitis following third molar extraction and to evaluate the safety and local tolerability.
- Trial name
- NCT02382809
- Testing
- DC071
- Where
- 18 sites in Estonia, France and 2 more
- Volunteers
- 414 people
- Sponsor
- Pierre Fabre Medicament
Dental Plaque, Gingivitis
The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis
The objective of this clinical research study is to assess the efficacy of three oral hygiene multi-component regimens encompassing the use of a manual toothbrush, toothpaste and a mouthwash in controlling established dental…
- Trial name
- NCT02193165
- Testing
- triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash, stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash, fluoride toothpaste + fluoride Mouthwash
- Where
- Puerto Rico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive