Clinical trials: Movement Disorders in Old Age
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Cognitive Dysfunction, Cognitive Dysfunction, Cognitive Disorder
China-NINE Cohort：Neuroimmune Network in Elderly / Neurodegeneration
This is an observational study aimed at understanding the cognitive, functional, and behavioral characteristics of Chinese patients with cognitive impairment, exploring the underlying mechanisms, and providing evidence for early…
- Conditions
- Cognitive Dysfunction, Cognitive Dysfunction, Cognitive Disorder, Parkinson's Disease (PD)
- Trial name
- NCT07586501
- Where
- 2 sites in China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Yantai Yuhuangding Hospital
Diabetes Mellitus Type 2, Impaired Balance in Elderly
Improvement Through Movement - Balance Control and Somatosensory Function in People With Diabetes Mellitus Type 2
This study focuses on improving balance control and somatosensory functions in individuals aged 60 years and older with diabetes mellitus tyoe 2 (DMT2).
- Conditions
- Diabetes Mellitus Type 2, Impaired Balance in Elderly, Somatosensory Disorders, Balance Control in Elderly
- Trial name
- NCT07786194
- Testing
- Balance control and exercise training, Relaxation and exercise training
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universiteit Antwerpen
Parkinson Disease, Delirium in Old Age
Parkinson's Disease: Risk Assessment of Persistent Delirium and Its Management
Background: delirium describes the change in people's behaviour and thinking when they are unwell. People with delirium may appear confused, have difficulty with organisation and can be different to their usual personality.
- Trial name
- PARADIGM (NCT05437458)
- Testing
- Delirium (exposure)
- Where
- United Kingdom
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Osteoarthritis, Knee
Effects of MatPilates in Pain and Functionality in Elderly Woman With Osteoarthritis.
Introduction: The osteoarthrosis is incurable, one of the most incapacitating disease around the world and your prevalence is increasing every year.
- Trial name
- NCT03321084
- Testing
- MatPliates, Control
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Maria das Graças Rodrigues de Araújo
Urinary Tract Infections, Infectious Diarrhea
Creation of an E-toileting Log Through Classification of the Physical Properties of Stool and Urine Using TrueLoo™
The purpose of this study is to assess the feasibility of TrueLoo™, an Internet-connected smart toilet seat, in accurately monitoring and logging bowel movements and urinations of residents in senior living facilities across…
- Conditions
- Urinary Tract Infections, Infectious Diarrhea, Clostridium Difficile Infection, Gastrointestinal Disease
- Trial name
- NCT05008640
- Testing
- TrueLoo™
- Where
- 6 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Toi Labs, Inc.
Old Age; Dementia, Swallowing Disorder
The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia
Swallowing impairment (dysphagia) is extremely common in older adults living with dementia due to age-related changes in swallowing and other disease-specific impairments.
- Conditions
- Old Age; Dementia, Swallowing Disorder, Cough, Parkinson Disease
- Trial name
- NCT04362228
- Testing
- Whole-body exercise
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- McMaster University
Elderly, Parkinsons Disease
BETA Study: Improving Balance Function in Elderly by Progressive and Specific Training and Physical Activity
Balance control, physical activity and health related quality of life will be assessed before and after a 10 to 12 weeks training program as well as 6 and 12 months thereafter in 200 elderly (>60) with balance problems (100 with…
- Conditions
- Elderly, Parkinsons Disease, Osteoporosis
- Trial name
- BETA (NCT01417598)
- Testing
- Gait and balance group training, Nordic walking (only osteoporosis group)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Parkinson Disease
Safety and Effectiveness of Opicapone Plus Standard of Care in Elderly Patients With Parkinson's Disease
The purpose of this study is to describe the safety and efficacy of opicapone plus standard of care in elderly patients with PD in the real-world setting
- Trial name
- NCT03959540
- Testing
- Opicapone, Levodopa (L-DOPA) + Standard care
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- Bial - Portela C S.A.
Parkinson's Disease
Reduction of Falls in the Elderly - Parkinson's Disease
The REFINE-PD study is a controlled trial embedded within a larger cluster controlled study (the IMPACT study). The study aims to investigate the efficacy of a multifactorial falls prevention program for patients with Parkinson's…
- Trial name
- REFINE-PD (NCT00518648)
- Testing
- Multifactorial fall prevention program, Usual care
- Where
- 6 sites in Netherlands
- Volunteers
- 187 people
- Sponsor
- Radboud University Medical Center
Accidental Fall, Postural Balance
The Relation Between Movement Patterns, Balance Performance, Function of the Inner Ear and Falls
Falls are one of the most common reasons for immobilisation and death in elderly population. This study aims at studying falls among a group of older people.
- Conditions
- Accidental Fall, Postural Balance, Movement Disorders in Old Age
- Trial name
- NCT03503916
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Lund University
PARKINSON DISEASE (Disorder), Aged 65 Years or Older
Multidimensional Assessment of Fatigability in Older Adults Living in Southern Switzerland and Elderly With Parkinson's Disease
With our study, the investigators aim to assess the impact of the fatigue experienced during daily life activities (tiredness) and whether there is a relationship with muscle fatigue during an exercise task.
- Trial name
- LifeLike (NCT07485218)
- Where
- 5 sites in Italy, Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Post-stroke, Parkinson Disease
Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients
The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related…
- Conditions
- Post-stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Mild Cognitive Impairment (MCI)
- Trial name
- VP_Adults (NCT07616050)
- Testing
- Dual-task training with Virtual Reality, Cycling training
- Where
- 7 sites in Italy
- Volunteers
- 70 people
- Sponsor
- Marta Mondellini
Frontotemporal Dementia, Dementia
Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)
The protocol is organized into three Phases - In Phase I an online training program will be developed in "Care of Persons with Dementia in their Environments" (COPE) -an evidence-based bio-behavioral dementia program -using…
- Conditions
- Frontotemporal Dementia, Dementia, Multi-Infarct Dementia, Vascular Dementia
- Trial name
- NCT04165213
- Testing
- Care of Older Persons in their Environment (COPE) online module training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cervical Spine Degeneration, Movement, Abnormal
Cervical Spine Motion in the Elderly
Rationale: Physiological motion of the cervical spine is a subject of interest for medical specialists. Segmental range of motion (sROM) has been most commonly used to define motion but inter- and intra-variability is large.
- Conditions
- Cervical Spine Degeneration, Movement, Abnormal, Aging
- Trial name
- NCT04222777
- Testing
- Cinematographic Recording
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Parkinson's Disease Patients
Bio-Feedback to Improving Stability in Elderly Population
Our hypothesis is that intensive training with positive biofeedback may enhance postural control and stability in Parkinson's disease patients and in elderly fallers.
- Trial name
- NCT00716261
- Testing
- McROB Hybrid node 3-axes accelerometers and 3-axes gyroscopes
- Where
- Israel
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson Disease
Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients
This study will determine whether glucose facilitates memory in healthy elderly people and those with Parkinson's disease.
- Trial name
- NCT00004451
- Testing
- Glucose
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Sarcopenia, Sarcopenia in Elderly
The Influence of Movement Velocity Biofeedback on Muscle Activation and Self Perception in Older Adults With Sarcopenia
The overall objective for this clinical trial is to provide evidence for internal and external cueing for physical therapists and other rehabilitation clinicians to optimize resistance training within rehabilitation for older…
- Conditions
- Sarcopenia, Sarcopenia in Elderly, Age-associated Muscle Loss
- Trial name
- NCT06853275
- Testing
- Experimental: External Focus, Other: Internal Focus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Creighton University
Healthy Elderly, Parkinson Disease
A Study to Assess Single and Multiple Doses of IkT-148009 in Healthy Elderly Participants and Parkinson's Patients
This study investigates the safety and tolerability of drug IkT-148009 in healthy elderly volunteers (55 to 70 years old). This first-in-human study is designed in 3 parts.
- Trial name
- NCT04350177
- Testing
- IkT-148009
- Where
- 4 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- ABLi Therapeutics, Inc.
Fall, Aging
PRE.C.I.S.A - Fall Prevention and Promotion of Active and Healthy Aging
Randomized Controlled Trial (RCT) aiming at assessing the efficacy of an interdisciplinary multi-component and personalized multi-factorial intervention for reducing falls at one year post-enrolment in comparison to the usual…
- Conditions
- Fall, Aging, Parkinson Disease, Stroke
- Trial name
- PRECISA (NCT03592420)
- Testing
- Interdisciplinary multicomponent interventions, Usual care
- Where
- 2 sites in Italy
- Volunteers
- 366 people
- Sponsor
- Azienda Unita' Sanitaria Locale Di Modena