Clinical trials: Moyamoya Syndrome
Moyamoya Disease
The Symani Restore Study
A research study for a neurosurgical procedure in adult patients with Moyamoya disease
- Trial name
- NCT07140731
- Testing
- Symani Surgical System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jacobs institute
Moyamoya Disease, Healthy
Cognitive-Motor Incorporated Training and Its Relations in Cerebrovascular Diseases With Cognitive and Motor Impairments
The following three-part proposal will explore the impact of applying motor-cognitive incorporated training (MCIT) in individuals with post-stroke cognitive impairment (PSCI) or Moyamoya disease (MMD), and examine the…
- Conditions
- Moyamoya Disease, Healthy, Stroke
- Trial name
- NCT07144930
- Testing
- MCIT program, Motor training program
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Moyamoya Disease, TIA
The Effect of RIC on TIA/Stroke in Children With Moyamoya Disease
Moyamoya disease is a common reason of transient ischemic attack (TIA) and stroke in children. Remote ischemic conditioning (RIC) has been shown to prevent recurrent stroke in intracranial arterial stenosis, but it is unclear…
- Conditions
- Moyamoya Disease, TIA, Children, Stroke
- Trial name
- RIC-PMD-1 (NCT03821181)
- Testing
- RIC group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Capital Medical University
Moyamoya Disease
Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya Disease
The purpose of this study is to investigate the effectiveness of statins in the treatment of moyamoya disease based on multimodal magnetic resonance imaging.
- Trial name
- SEST-MOYA (NCT06817434)
- Testing
- Revascularization/Conservative management
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Attack, Ischemic Stroke
Multiple Burrhole Therapy With Erythropoietin for Unstable Moyamoya
In this study, the investigators aim to evaluate the indirect revascularization outcomes of a new combination therapy of multiple burrhole procedure with promotion of arteriogenesis by intravenous (IV) erythropoietin (EPO)…
- Conditions
- Ischemic Attack, Ischemic Stroke, Moyamoya Disease, Burr Hole
- Trial name
- NCT03162588
- Testing
- erythropoietin
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Ajou University School of Medicine
Moyamoya Disease, Intracranial Hemorrhages
5T MRI and Metabolomics-Based Hemorrhage Risk Prediction in Moyamoya Disease
Intracranial hemorrhage is a leading cause of death and disability in patients with moyamoya disease (MMD), yet clinically available tools for predicting long-term hemorrhage risk are lacking.
- Conditions
- Moyamoya Disease, Intracranial Hemorrhages, Stroke
- Trial name
- NCT07781579
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Moyamoya Disease, Intracranial Atherosclerotic Stroke
Moyamoya Disease Biomarkers in Patients With Intracranial Atherosclerotic Stroke
The aim of this study is to investigate the proportion of patients with moyamoya disease among the patients who were diagnosed as having intracranial atherosclerotic stroke.
- Conditions
- Moyamoya Disease, Intracranial Atherosclerotic Stroke, Intracranial Steno-occlusive Disease
- Trial name
- NCT02074111
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Moyamoya Disease
Biomarker-Led Optimization of Successful Surgical Outcomes in Moyamoya
The goal of this work is to use advanced magnetic resonance imaging (MRI) methods to assess brain blood flow and vascular function in adults with moyamoya disease (MMD).
- Trial name
- BLOSSOM (NCT06634004)
- Testing
- BOLD MRI
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Moyamoya Disease
Effect of Surgical Revascularization on Hemorrhagic Moyamoya Disease
Moyamoya Disease(MMD), also known as spontaneous basilar artery occlusion, is characterized by the gradual thickening of arterial intima at the distal carotid artery and the proximal portion of anterior/middle cerebral artery…
- Trial name
- ESRHMMD (NCT03627975)
- Testing
- Conservative treatment
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Moyamoya Disease
Neurocognitive and Radiological Assessments in Adult Moyamoya Undergoing Surgery
Adult patients with moyamoya disease (MMD) are reported to suffer from considerable impairment of executive function/attention. Although reduced cerebrovascular reserve (CVR) in frontal areas has been detected by perfusion MRI…
- Trial name
- NRAAMUS (NCT02305407)
- Testing
- Surgical Revascularization, Conservative treatment
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
EEG With Periodic Abnormalities
EEG Monitoring in Children With Moyamoya Disease
EEG in moyamoya disease in children preoperatively
- Trial name
- NCT03173014
- Testing
- EEG
- Where
- 2 sites in South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Moyamoya Disease, Moyamoya
Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression.
- Trial name
- IMAGINE (NCT06330818)
- Testing
- MRI, H2 15O PET/CT, Biosampling
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Moyamoya Disease
Efficacy and Safety of rTMS for Cognitive Rehabilitation in Moyamoya Disease
The purpose of this study is to evaluate the safety and effectiveness of transcranial magnetic stimulation (TMS) therapy in moyamoya patients who received surgical revascularization.
- Trial name
- NCT03543748
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 50 people
- Sponsor
- Huashan Hospital
Moyamoya Disease, Magnetic Resonance Imaging
Predicative Value of Multimodal MRI in Moyamoya Disease
Moyamoya disease (MMD) is a nonatherosclerotic cerebrovascular abnormality, characterized by a progressive stenosis or occlusion of the intracranial internal carotid arteries (ICAs) and their proximal branches, with subsequent…
- Trial name
- NCT03785171
- Testing
- surgical revascularization
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Moyamoya Disease
Long-term Outcomes of Conservative Management in Patients with Moyamoya Disease and Their First-degree Relatives (LAMORA)
The purpose of this study is to investigate the long-term outcomes of conservative management in patients with moyamoya disease and their first-degree relatives, and provide potential pathogenesis of moyamoya disease.
- Trial name
- NCT05332756
- Testing
- Conservative management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Tiantan Hospital
Brain Neoplasm, Intracranial Aneurysm
Subclavian Vein catheterization_Seldinger Vs Modified Seldinger
Seldinger technique is a minimally invasive technique in which the practitioner accesses the target vessel with a small bore needle, then dilates to the size required for the catheter.
- Conditions
- Brain Neoplasm, Intracranial Aneurysm, Cerebrovascular Moyamoya Disease
- Trial name
- MS (NCT02090010)
- Testing
- Seldinger technique, Modified Seldinger technique
- Where
- South Korea
- Volunteers
- 418 people
- Sponsor
- Seoul National University Hospital
Moyamoya Disease, Pediatrics
Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients
This study evaluates the effect of recombinant human erythropoietin (rHuEPO) on the neovascularization of pediatric moyamoya disease patients.
- Conditions
- Moyamoya Disease, Pediatrics, Cerebrovascular Disorders
- Trial name
- NCT03882060
- Testing
- erythropoietin, Normal saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Moyamoya Disease, Moyamoya Syndrome
Development and Validation of Risk Prediction Models for Stroke and Cognitive Impairment in Moyamoya Disease and Moyamoya Syndrome
This multicenter prospective observational cohort study aims to develop and validate individualized risk prediction models for stroke and cognitive decline in patients with moyamoya disease or moyamoya syndrome by integrating…
- Trial name
- NCT07894107
- Where
- 13 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Tiantan Hospital
Moyamoya Disease
Functional Magnetic Resonance-Based Observations of Brain Networks in Moyamoya Disease Patients Under Anesthesia
Moyamoya disease is characterized by progressive stenosis of the genesis of the distal internal carotid arteries bilaterally and progressive generation of compensatory pathological vascular networks at the basis cranii, and these…
- Trial name
- NCT06041659
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Beijing Tiantan Hospital
Moyamoya Disease
The Role of m6A RNA Modification in Moyamoya Disease
The purpose of this study is to detect the change of m6A RNA modification from peripheral blood of patients with moyamoya disease, and to assess the relationship between clinical characteristics.
- Trial name
- NCT04696094
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital