Clinical trials: Mucocutaneous Lymph Node Syndrome
Kawasaki Disease
A Study to Evaluate the Use and Safety of CARDIOLITE® in Pediatric Patients With Kawasaki Disease
Determine the predictive value of CARDIOLITE® rest and stress myocardial perfusion imaging (MPI) to define a pediatric population with Kawasaki Disease (KD) at high and low risk of developing cardiac events.
- Trial name
- NCT00162032
- Testing
- Sestamibi
- Where
- 50 sites in United States, Brazil and 5 more
- Volunteers
- 445 people
- Sponsor
- Lantheus Medical Imaging
Kawasaki Disease, Children
Anakinra and Kawasaki Disease
The study is designed to assess the efficacy and safety of anakinra, an interleukin 1 receptor antagonist, in patients with Kawasaki disease who failed to respond to standard treatment:e.g.
- Trial name
- KAWAKINRA (NCT02390596)
- Testing
- Anakinra
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kawasaki Disease, Appendicitis
Acute Abdomen in Kawasaki Disease
Clinical and histopathological description of three cases of Kawasaki disease with acute abdomen.
- Trial name
- NCT03902262
- Testing
- appendicectomy
- Volunteers
- 3 people
- Sponsor
- National Institute of Pediatrics, Mexico
Kawasaki Disease
Different Doses of IVIG for Kawasaki Disease
The objective of this study is to investigate the effect of different doses of intravenous immunoglobulin (IVIG) (1g/kg once, 1g/kg twice, 2g/kg once) for Kawasaki disease (KD) in a multicentre, prospective,randomised trial.
- Trial name
- NCT02439996
- Testing
- IVIG (1g/kg,once), IVIG (1g/kg,twice), IVIG (2g/kg.once)
- Where
- China
- Volunteers
- 404 people
- Sponsor
- Children's Hospital of Fudan University
Kawasaki Disease
A Multi-center, Randomized to Compare the Efficacy of IVIG Alone and IVIG Plus High-dose Aspirin in Kawasaki Disease
Kawasaki disease (KD) is an acute febrile systemic vasculitis most commonly seen in children under the age of 5 years old. This trial has been designed as a multi-center, prospective, randomized controlled, evaluator-blinded…
- Trial name
- NCT02951234
- Testing
- IVIG only, IVIG and Aspirin
- Where
- 5 sites in Taiwan
- Volunteers
- 278 people
- Sponsor
- Chang Gung Memorial Hospital
Kawasaki Disease
Prevalence and Early Markers of Atherosclerosis in Adults With a History of Kawasaki Disease
Kawasaki disease (KD) is an acute systemic vasculitic syndrome with coronary tropism. It has been reported worldwide, but it is ten times more common in Asian population.
- Trial name
- Kawasaki (NCT01440075)
- Testing
- Cardiac evaluation
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Kawasaki Disease, Steroid
A Trial to Evaluate the Efficacy of Immunoglobulin Plus Steroid for Prevention of Coronary Artery Abnormalities in Taiwanese Refractory Kawasaki Disease (RAST Study)
Background: Kawasaki disease (KD), most popular acquired heart disease in childhood, is characterized by diffuse vasculitis, especially on the middle-sized muscular arteries. IVIG and aspirin are currently standard treatment.
- Conditions
- Kawasaki Disease, Steroid, Immuoglobulin
- Trial name
- RAST (NCT03200561)
- Testing
- Prednisolone, immunoglobulin
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Kawasaki Disease
Study of Efficacy and Safety of Canakinumab in Pediatric Patients With Kawasaki Disease
The purpose of this trial is to evaluate whether, in Intravenous Immunoglobulin-naïve or refractory patients diagnosed with active Kawasaki disease, administration of canakinumab controls fever and acute phase reactants.
- Trial name
- NCT02980263
- Testing
- Canakinumab
- Sponsor
- Novartis Pharmaceuticals
Kawasaki Disease
Measurement of Antibodies in Adults With a History of Kawasaki Disease
Kawasaki disease (KD) is an acute systemic vasculitic syndrome with coronary tropism. It has been reported worldwide, but it is ten times more common in Asian population.
- Trial name
- KAWASAKI Ac (NCT02853266)
- Testing
- laboratory biomarker analysis
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Kawasaki Disease
Safety and Vascular Remodelling After BVS Implantation for Stenotic or Occluded Lesions in Children and Young Adults With KD.
To investigate the safety and long-term vascular remodeling after bioresorbable vascular scaffold (BVS) implantation for stenotic or occluded lesion in children or young adults with Kawasaki disease (KD).
- Trial name
- NCT02771288
- Testing
- Bioresorbable Vascular Scaffold
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Kawasaki Disease
Cardiovascular Risk Markers and Response to Statins After Kawasaki Disease
The purpose of this study is to determine whether Chilean children with history of Kawasaki disease have endothelial dysfunction years after the acute phase of the disease, and if this condition can be modified by treatment with…
- Trial name
- NCT00305201
- Testing
- pravastatin
- Where
- Chile
- Sponsor
- Pontificia Universidad Catolica de Chile
Kawasaki Disease
Epidemiologic Features of Kawasaki Disease in Shanghai From 2008 Through 2012
To investigate the epidemiological pictures of Kawasaki disease (KD) in Shanghai from 2008 through 2012, and illustrate the risk factors of coronary arterial lesions .
- Trial name
- NCT02317913
- Where
- China
- Volunteers
- 2,402 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Kawasaki Disease
Infliximab for Kawasaki Disease Patients Resistant to IVIG : a Multicentre, Prospective, Randomised Trial
The objective of this study is to investigate the effect of infliximab to the children who don't respond to the first dose of intravenous immunoglobulin (IVIG) (2g/kg) in Kawasaki disease.
- Trial name
- NCT02298062
- Testing
- Infliximab, IVIG
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fudan University
Kawasaki Disease
Multi-center Prospective Randomized Control Trail of High Dose Aspirin in Acute Stage of Kawasaki Disease
Kawasaki disease (KD) is an acute multi-system vasculitis syndrome of unknown etiology occurring mostly in infants and children younger than 5 years of age.
- Trial name
- NCT02359643
- Testing
- Aspirin
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Kawasaki Disease
Etiology Study of Kawasaki Disease
The purpose of this study is to investigate the infectious etiology of Kawasaki disease (KD); a prospective household and case control study for Kawasaki disease will be done.
- Trial name
- NCT00154596
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Kawasaki Disease
Infliximab Plus Intravenous Immunoglobulin for the Primary Treatment of Kawasaki Disease
The purpose of this study is to determine whether the addition of infliximab to standard primary therapy of intravenous immunoglobulin (IVIG) and high dose aspirin will reduce resistance to therapy in acute Kawasaki disease (KD).
- Trial name
- NCT00760435
- Testing
- Infliximab
- Where
- 2 sites in United States
- Volunteers
- 196 people
- Sponsor
- University of California, San Diego
Giant Cell Arteritis, Takayasu's Arteritis
Reproductive Health in Men and Women With Vasculitis
The purpose of this study is to learn about reproductive health, including fertility and pregnancies, in people with vasculitis.
- Conditions
- Giant Cell Arteritis, Takayasu's Arteritis, Polyarteritis Nodosa, Wegener's Granulomatosis
- Trial name
- NCT02176070
- Where
- United States
- Volunteers
- 467 people
- Sponsor
- University of South Florida
Kawasaki Disease, Aneurysm, Coronary
Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease
Background Kawasaki disease (KD) is characterized by fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy.
- Trial name
- NCT02114099
- Testing
- Atorvastatin
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Cardiovascular Diseases, Coronary Aneurysm
Prevention of Coronary Aneurysms in Kawasaki Syndrome
To test the efficacy of intravenous gamma globulin (IVGG) in preventing coronary artery aneurysms in children with Kawasaki Syndrome.
- Conditions
- Cardiovascular Diseases, Coronary Aneurysm, Heart Diseases, Mucocutaneous Lymph Node Syndrome
- Trial name
- NCT00000520
- Testing
- immunoglobulins, intravenous, aspirin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Kawasaki Disease
Study of Combined Therapy of Aspirin and "IVIG-SN" in Kawasaki Disease
The purpose of this study is to evaluate the safety, efficacy and of Immune Globulin Intravenous (Human) IVIG-SN™ in subjects with kawasaki diseases.
- Trial name
- NCT01524939
- Testing
- immunoglobulin G
- Where
- 7 sites in South Korea
- Volunteers
- 45 people
- Sponsor
- Green Cross Corporation