Clinical trials: Mucositis
Autologous Stem Cell Transplant
High Heated Humidity in Stem Cell Transplant
The purpose of this study is to find out what effects of high heated humidity has on you and your mucositis.
- Trial name
- NCT05358262
- Testing
- Airvo, Standard of Care
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- AHS Cancer Control Alberta
Breakthrough Pain, Mucositis
Intranasal Transmucosal Fentanyl Pectin for Breakthrough Cancer Pain in Radiation-induced Oropharyngeal Mucositis
An open-label, non-randomized study to assess the titration, safety and efficacy of intranasal fentanyl pectin nasal spray for the treatment of secondary breakthrough pain secondary to radiation-induced mucositis in patients with…
- Conditions
- Breakthrough Pain, Mucositis, Radiotherapy, Chemotherapy
- Trial name
- CP073 (NCT02050503)
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Grupo de Investigación Clínica en Oncología Radioterapia
Methamphetamine-dependence, Rectal Gonorrhea
Inflammation in Methamphetamine and STIs (IMSTI)
This clinical trial aims to investigate the effects of a decline in methamphetamine use on rectal inflammatory cytokine levels, substance use contexts, and HIV/STI risk behavior.
- Conditions
- Methamphetamine-dependence, Rectal Gonorrhea, Rectal Chlamydia
- Trial name
- IMSTI (NCT05162391)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Multiple Myeloma
Anakinra: Safety and Efficacy in the Management of Fever During Neutropenia and Mucositis in ASCT
Oral and intestinal mucositis are major risk factors for the occurrence of fever during neutropenia and bloodstream infections after intensive chemo- and radiotherapy.
- Trial name
- AFFECT-1 (NCT03233776)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 9 people
- Sponsor
- Radboud University Medical Center
Peri-implant Mucositis
Non-surgical Treatment of Peri-implant Mucositis: FMUD vs FMUD and Air-Flow Master Piezon®
The aim of the present study is to evaluate the adjunctive effect of glycine-powder air-polishing (GPAP) to full-mouth ultrasonic debridement (Fm-UD) in the treatment of peri-implant mucositis, and to determine the predictive…
- Trial name
- NCT05801315
- Testing
- Glycine powder air polishing, Full mouth ultrasonic debridement
- Where
- Italy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Siena
Mucositis, Hematopoietic Stem Cell Transplantation
Oral Selenium Therapy for the Prevention of Mucositis
Selenium as an antioxidant and anti-inflammatory agent could be effective in prevention of mucositis induced by chemotherapy and radiotherapy.
- Trial name
- NCT01432873
- Testing
- Oral selenium
- Where
- Iran
- Volunteers
- 76 people
- Sponsor
- Tehran University of Medical Sciences
Mucositis Oral
Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Peri-implant disease is an inflammatory process of bacterial etiology that can affect the tissues around the implants and can be classified as peri-implant mucositis or peri-implantitis.
- Trial name
- Mucosite prob (NCT04187222)
- Testing
- Mechanical debridements, Bifidobacterium animalis subsp. lactis
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Peri-Implantitis and Peri-implant Mucositis
Non Surgical Treatment of Periimplantitis
20 consecutive adult implant patients, presenting the signs of peri-implant mucositis (probing depth ≥4 mm combined with bleeding and/or pus on probing) or initial peri-implantitis (probing depth ≥4 mm, bleeding and suppuration…
- Trial name
- NCT02023853
- Testing
- ultrasonic, erythritol, metronidazole gel
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Proed, Torino, Italy
Mucositis (MeSH Unique ID: D052016), Stomatitis (MeSH Unique ID: D013280)
OZOCLO_MUCOSITIS: a New Protocol for Prevention of Oral Mucositis
Oral mucositis (OM) is a significant side effect of cytotoxic anti-cancer chemotherapy and HN radiotherapy. CT-associated OM (CT-OM). It is the ulcerative phase that is most painful and associated with poor health outcomes.
- Trial name
- OZOCLO_MUCOS (NCT05211622)
- Testing
- 1. alpha acid lipoic - tables, 2. ozonated oil - mouthwash, 3. chlorhexidine 0,2% - mouthwash
- Volunteers
- 80 people
- Sponsor
- University of Palermo
Vaginitis, Radiotherapy Induced Mucositis
Clinical Study on the Prevention and Treatment of Radiation Vaginitis With Triethanolamine Cream
The objective of this clinical trial is to understand whether triethanolamine cream can prevent and treat acute radiation vaginitis. It will also learn about the safety of triethanolamine cream.
- Trial name
- NCT07492654
- Testing
- Trolamine (Biafine)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Oral Mucositis, Bone Marrow Transplant Complications
Assessment of Efficacy of LightWalker (Nd:Yag, Er:Yag) Laser Therapy on Incidence, Severity and Duration of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation (HSCT). Prospective Randomized Open-label Study
Oral mucositis (OM) is a common and debilitating adverse effect of conditioning regimens in patients undergoing hematopoietic cell transplantation (HCT). It is treated symptomatically with pain relief medications.
- Trial name
- NCT05175222
- Testing
- Laser therapy
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Peri-implant Mucositis
The Efficacy of Stabilized Chlorine Dioxide Rinse as a Chemical Adjuvant for Treatment of Per-implant Mucositis
A full understanding of etiology and diagnosis of peri-implant diseases is crucial for finding effective treatments for these diseases that are more widely accessible to dentists.
- Trial name
- NCT04838054
- Testing
- Stabilized chlorine dioxide oral rinse
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Inflammatory Bowel Diseases, Crohn Disease
Remote Monitoring of IBD
Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) with a heterogeneous disease course.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT05886322
- Testing
- patient reported outcome measures, fecal calprotectin, colonoscopy
- Where
- 5 sites in Netherlands
- Volunteers
- 400 people
- Sponsor
- Maastricht University Medical Center
Mucositis Oral, Head & Neck Cancer
Photobiomodulation Alone Versus Photobiomodulation Combined With Topical Oral Oxygen Therapy for Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized Clinical Trial
Oral mucositis is the inflammation and ulceration of the mucous membranes within the oral cavity, characterized by atrophy, edema, and erythema (1), and it occurs in nearly all patients with advanced head and neck cancer (HNC)…
- Trial name
- NCT07865780
- Testing
- sirolase xtent laser, blue m gel
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Assiut University
Oral Mucositis, Head and Neck Cancer
Dose Ranging Study to Assess the Safety and Efficacy of SCV-07 for the Delay to Onset of Severe Oral Mucositis in Patients Receiving Chemoradiation Therapy for Head and Neck Cancer
Oral Mucositis (OM) is a painful and debilitating side effect of many of the drug or radiation regiments used to treat cancer. This study examines the investigational drug SCV-07 and it's possible application in treating Oral…
- Trial name
- SCV-07 OM (NCT00756951)
- Testing
- SCV-07
- Where
- 19 sites in United States
- Volunteers
- 59 people
- Sponsor
- SciClone Pharmaceuticals
Mucositis Oral
Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis
Oral mucositis consequences can range from pain, decreased oral intake, impaired speech and swallowing to adverse events as severe as septicemia, increased hospitalization, and G-tube feeding A wide variety of agents have been…
- Trial name
- NCT04303312
- Testing
- Benzydamine Hydrochloride, Solcoseryl and pumpkin seed oil
- Volunteers
- 54 people
- Sponsor
- Ghada zaki
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation
Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients
The overall purpose of this clinical study is to evaluate safety and efficacy of the MuReva Phototherapy System with a light delivery mouthpiece to reduce the severity of oral mucositis (OM) in adult patients with squamous cell…
- Conditions
- Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
- Trial name
- NCT03972527
- Testing
- Photobiomodulation, Routine Oral Care and Analgesia
- Where
- 12 sites in United States
- Volunteers
- 85 people
- Sponsor
- MuReva Phototherapy Inc.
Peri-implantitis, Peri-implant Mucositis
Peri-Implant Sulcus Fluid Stress Markers in Health and Disease
This study examines the association between psychosocial stress and peri-implant diseases. Peri-implant diseases are inflammatory conditions affecting the tissues around dental implants and may contribute to implant failure.
- Conditions
- Peri-implantitis, Peri-implant Mucositis, Peri-Implant Health
- Trial name
- NCT07353515
- Testing
- Psychological Assessment, Peri-implant Sulcular Fluid Biomarker Analysis, Peri-implant Clinical Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Inonu University
Nursing Education
The Effects of Contextual-Based Augmented Reality Facilitated Education in Promoting Oral Mucositis Care Among Nurses
In recent years, cancer has become one of the leading causes of death worldwide, with an increasing number of people being diagnosed with the disease.
- Trial name
- NCT07327333
- Testing
- Situational Augmented Reality-Assisted Teaching, Classroom Teaching
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Mackay Memorial Hospital
Head and Neck Cancer, Radiation-Induced Mucositis
A Randomized Controlled Study on the Improvement of Medical Experience for Patients With Radiation-induced Oropharyngeal Mucositis Based on the RIS System of the Internet of Things
This study is a researcher-initiated, multi-center, prospective, two-arm interventional randomized controlled study across the country.
- Trial name
- NCT07126457
- Testing
- RIS system
- Where
- 4 sites in China
- Volunteers
- 110 people
- Sponsor
- Nanfang Hospital, Southern Medical University