Clinical trials: Mucositis
Head and Neck Cancer, Oral Mucositis
The Effect of Hydrogen Water in Oral Mucositis in Head and Neck Cancer Patients After Therapy
Inpatients or outpatients diagnosed with head and neck cancer who met the inclusion and exclusion criteria were referred to the co-investigator(Dr. Chih-Jen Huang and Dr.
- Conditions
- Head and Neck Cancer, Oral Mucositis, Pain, Quality of Life
- Trial name
- NCT05913895
- Testing
- hydrogen water
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Oral Mucositis
Efficacy of Orosol® in the Treatment of Chemo- and Radiation-induced Mucositis.
Oral mucositis is one of the most debilitating side effects of radiation therapy and various forms of chemotherapy, especially for head and neck cancers and hematopoietic stem cell transplants.
- Trial name
- OROSOL (NCT05161091)
- Testing
- Topical application of Orosol®
- Where
- 2 sites in France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Clermont-Ferrand
Radiotherapy-induced Oral Mucositis
Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.
Evaluate the effectiveness and safety of traditional Chinese medicine compound in improving radiotherapy-induced oral mucositis in patients with head and neck malignant tumors.
- Trial name
- NCT07339774
- Testing
- Zishui Daohuo oral liquid combined with Kujiu mouthwash, Radiotherapy
- Where
- China
- Volunteers
- 128 people
- Sponsor
- West China Hospital
Oral Mucositis
A Mouthwash Medicine for the Reduction or Prevention of Mouth Ulceration Caused by Radiotherapy for Head and Neck Cancer
This study is looking at a new medication called NG11-2 to see if it can reduce a side effect called severe Radiation-induced Oral Mucositis (RIOM) that can happen to people getting radiation treatment for head and neck cancer.
- Trial name
- NCT06669390
- Testing
- NG11-2
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- VasoDynamics Ltd
Head and Neck Squamous Cell Carcinoma
Streptococcus Salivarius K12 for Prevention and Treatment of Oral Mucositis in Patients Undergoing Radiotherapy
To evaluate the efficacy and safety of Streptococcus salivarius K12 for prevention and treatment of oral mucositis in patients undergoing radiotherapy for malignant head and neck tumors.
- Trial name
- NCT05918224
- Testing
- Streptococcus salivarius K12, Streptococcus salivarius K12 simulants
- Where
- China
- Volunteers
- 160 people
- Sponsor
- West China Hospital
Oral Mucositis, Pediatric Cancer
Curcumin VS Photo-bio-modulation Therapy of Oral Mucositis in Pediatric Patients Undergoing Anti-Cancer Non-invasive Treatment
The main objective of this study is to assess the impact of non-invasive photodynamic therapy by Curcumin and photo-bio-modulation low level (LL) laser treatment in managing mucositis induced by chemotherapy in pediatric…
- Trial name
- NCT06044142
- Testing
- Curcumin, Laser
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Riyadh Elm University
Pain, Mucositis
Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy
Stomatitis/oral mucositis is a common side effect to chemotherapy. Stomatitis is often associated with painful ulcers in the mouth.
- Trial name
- NCT00357942
- Testing
- morphine solution for injection, morphine mouthwash
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Danish University of Pharmaceutical Sciences
Blood Stem Cell Transplant Failure, Oral Mucositis
The Effect of Nursing Education on Oral Mucositis in Bone Marrow Transplant Patients
In this study, it is aimed to examine the effect of oral care training for oral mucositis, which will be given by the researcher to patients who have undergone bone marrow transplantation, on the incidence and severity of oral…
- Conditions
- Blood Stem Cell Transplant Failure, Oral Mucositis, Nurse's Role
- Trial name
- NCT05705622
- Testing
- Oral mukositis nurse's education for patients
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Head Cancer, Neck Cancer
Transcutaneous Electrical Nerve Stimulation (TENS) and Head and Neck Cancer Pain (HNC) (TENS & HNC)
The overall goal of this study is to examine the effect of a single dose of TENS on mucositis pain and function secondary to head and neck radiation therapies.
- Conditions
- Head Cancer, Neck Cancer, Pain
- Trial name
- NCT01194466
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Jennifer E. Lee
Locally Advanced Nasopharyngeal Carcinoma
Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy
The purpose of this study was to investigate the role of immunonutrion compared with standard nutrition in reducing oral mucositis in patients with locally advanced nasopharyngeal carcinoma.
- Trial name
- NCT05892354
- Testing
- Enteral immunonutrition, Standard enteral nutrition
- Where
- 20 sites in China
- Volunteers
- 190 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Radiation Induced Oral Mucositis
A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer
The purpose of the phase 2, GT-201 clinical study is to determine if GC4419 administered prior to intensity-modulated radiation therapy (IMRT) reduces the incidence, duration, and severity of radiation induced oral mucositis in…
- Trial name
- NCT02508389
- Testing
- Low Dose GC4419: 30mg/day, High Dose GC4419: 90mg/day, Intensity-Modulated Radiation Therapy
- Where
- 64 sites in United States, Canada and 1 more
- Volunteers
- 223 people
- Sponsor
- Galera Therapeutics, Inc.
Apoptosis, Apoptosis Regulatory Proteins
Genomic and Proteomic Analyses of Apoptosis Mechanisms in Diseased Peri-implant Tissue
A total of 72 individuals were included in the study: 23 with peri-implant mucositis, 25 with peri-implantitis, and 24 healthy controls.
- Conditions
- Apoptosis, Apoptosis Regulatory Proteins, Proteases, Peri-Implantitis and Peri-implant Mucositis
- Trial name
- NCT06865976
- Testing
- Non-Surgical Intervention, Surgical peri-implant therapy, Second stage surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Mucositis, Peri-implantitis
Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis
Evaluate clinically and microbiologically the effect of the oral probiotic Lactobacillus reuteri Prodentis (PerioBalance®, Sunstar, Switzerland) on implants with mucositis or periimplantitis, as a coadjuvant treatment of…
- Trial name
- NCT03047291
- Testing
- Probiotic
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-implant Health, Free Gingival Graft
Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts on Peri-implant Mucosa
This study aims to evaluate the effects of autogenous grafts harvested from different palatal regions on the peri-implant mucosa when applied during second-stage dental implant surgery.
- Conditions
- Peri-implant Health, Free Gingival Graft, Peri-implant Mucositis
- Trial name
- NCT07330609
- Testing
- Coronal palatal tissue, Apical palatal tissue
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Head and Neck Cancer
A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy
The purpose of this study is to evaluate the efficacy, safety and tolerability of palifermin on the incidence of oral mucositis in subjects with locally advanced head and neck cancer receiving postoperative radiotherapy.
- Trial name
- NCT00540332
- Testing
- palifermin
- Sponsor
- Swedish Orphan Biovitrum
Oral Mucositis
Effect of Black Mulberry Lollipop on Prevention of Oral Mucositis in Children
THE EFFECT OF BLACK MULBERRY LOLLIPOP AND SODIUM BICARBONATE USED IN ORAL CARE ON PREVENTION OF ORAL MUCOSITIS AMONG CHILDREN RECEIVING CHEMOTHERAPY DUE TO CANCER
- Trial name
- NCT04800549
- Testing
- Oral Mucositis
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sapanca Ilce Devlet Hastanesi
Mucositis, Head and Neck Cancer
Photobiomodulation Home-use Device for Prevention or Treatment of Oral Mucositis in Patients With Head&Neck Malignancies
Patients with head and neck malignancy that are treated with Radiation Therapy [RT] are expected to develop Oral Mucositis (OM) in 60% of cases.
- Conditions
- Mucositis, Head and Neck Cancer, Radiotherapy Side Effect
- Trial name
- PBM&OM-01 (NCT05176834)
- Testing
- B-Cure laser pro
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Erika Carmel ltd
Oral Mucositis (Ulcerative) Due to Radiation
Aerosolized Mesenchymal Stem Cell-Derived Exosomes for the Prevention and Treatment of Radiation-Induced Oral Mucositis
Radiation-induced oral mucositis (RIOM) is an inevitable acute complication in radiotherapy for head and neck malignancies, characterized by a complex pathogenesis involving multiple biological processes.
- Trial name
- NCT07312656
- Testing
- mesenchymal stem cell-derived exosomes
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Oral Mucositis, Head and Neck Cancer
EN3285 for the Prevention or Delay of Oral Mucositis in Patients With Head and Neck Cancer
Randomized, double-blind, placebo-controlled study for the treatment of head and neck cancer(HNC), to assess the ability of EN3285 to prevent or delay the onset of severe oral mucositis(OM).
- Trial name
- NCT00574860
- Testing
- EN3285, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Cancer, Nasopharyngeal Carcinoma
Assessing Manual Acupuncture's Impact on Mucositis From Nasopharynx Cancer Radiotherapy: A Visual Analogue Scale (VAS) and Quality of Life Study
The goal of this clinical trial is to learn if acupuncture can play a role in reducing pain and improving the quality of life of post-radiotherapy nasopharyngeal cancer mucositis patients.
- Conditions
- Cancer, Nasopharyngeal Carcinoma, Mucositis
- Trial name
- NCT06472024
- Testing
- Verum Acupuncture
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia