Clinical trials: Multiple Fracture Ribs
Rib Fractures
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
Rib fractures cause a significant amount of pain and are associated with an increased risk of lung infections, long hospitalization, and increased cost.
- Trial name
- NCT07145346
- Testing
- Suzetrigine (SUZ)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Rib Fractures, Rib Trauma
Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib Fractures
The study aims to investigate the effect of surgical stabilisation of rib fractures (SSRF) on clinical outcomes measured during the hospital stay (mortality, days on a mechanical ventilator, intensive care unit and hospital…
- Conditions
- Rib Fractures, Rib Trauma, Rib Fracture Multiple, Thorax; Fracture
- Trial name
- NCT06464302
- Testing
- Surgical stabilisation of rib fractures (SSRF), Non-operative management of rib fractures
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- University Hospital Muenster
Pain, Acute, Rib Fractures
Mid-point to Pleura Transverse Process Block Versus Thoracic Intervertebral Foramen Block
The analgesic effect of continuous mid-point to pleura transverse process block compared to the analgesic effect of continuous thoracic intervertebral foramen block, in patients with multiple rib fractures.
- Conditions
- Pain, Acute, Rib Fractures, Polytrauma
- Trial name
- NCT05348330
- Testing
- Thoracic intervertebral foramen block, Mid-point to pleura transverse process block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Rib Fractures
INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures
This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple…
- Trial name
- NCT05642026
- Testing
- Ropivacaine, Non steroidal anti-inflammatory drug and opioids
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Zachary Warriner
Flail Chest, Rib Fractures
Mortality Causes in Rib Surgery Patients
This study retrospectively investigates the causes of mortality and morbidity in patients undergoing rib fracture surgery due to blunt trauma.
- Conditions
- Flail Chest, Rib Fractures, Thoracic Injuries, Pulmonary Contusion
- Trial name
- NCT06755723
- Testing
- Rib fractures manangement
- Volunteers
- 112 people
- Sponsor
- Caner İşevi, MD
Rib Fracture Multiple
Multicenter RCT of SSRF in Non Flail Patients
This study evaluates the efficacy of surgical stabilization of rib fractures, as compared to best medical management, for patients with multiple, displaced rib fractures.
- Trial name
- CWISNONFLAIL (NCT03221595)
- Testing
- Operative
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Denver Health and Hospital Authority
Pain, Postoperative, Rib Fracture Multiple
Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures
To determine if patients with intraoperative cryoablation have better analgesia results compared to the control group of Surgical Stabilization of Rib Fractures (SSRF) without cryoablation
- Trial name
- NCT05415384
- Testing
- Cryoablation of Intercostal Nerves, Standard surgical treatment of patients with multiple rib fractures
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Rib Fracture Multiple
Serratus Anterior Plane Block for Improving Pain and Respiratory Function in Patients With Multiple Rib Fractures
This is an observational study which will evaluate the efficacy of the serratus anterior plane block for treating pain and respiratory capacity in patients with multiple rib fractures.
- Trial name
- NCT04311827
- Testing
- Serratus Anterior Plane Block
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Stanford University
Rib Fracture Multiple
Erector Spinae Plane Block vs Paravertebral Block for Pain Management in Fractured Ribs
Rib fractures pose a significant healthcare burden with its associated morbidity, long term disability, and mortality. Pulmonary morbidity is increased in these patients as a result of diminished gas exchange from fracture…
- Trial name
- NCT03883958
- Testing
- Erector Spinae Plane Block, Paravertebral Block
- Volunteers
- 60 people
- Sponsor
- Assiut University
Blunt Injury of Thorax, Flail Chest
Treatment of Acute, Unstable Chest Wall Injuries
Unstable chest injuries are common in poly trauma patients. They can lead to severe pulmonary restriction, loss of lung volume, difficulty with ventilation and can render the patient to require intubation and mechanical…
- Conditions
- Blunt Injury of Thorax, Flail Chest, Chest Wall Injury Trauma, Rib Fracture
- Trial name
- NCT01367951
- Testing
- Surgical fixation
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Unity Health Toronto
Flail Chest
MatrixRIB Implants for Surgical Stabilization of Flail Chest Injuries: A Registry
The purpose of this observational study is to document the treatment of serial rib fractures with MatrixRIB implants in a registry.
- Trial name
- MatrixRIB (NCT00810251)
- Testing
- MatrixRIB (FDA Approval # K081623)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Legacy Biomechanics Laboratory
Rib Fracture, Rib Fracture Multiple
Orthosis of Acute Traumatic Rib Fractures Via RibFx Belt for Pain Alleviation and Improved Pulmonary Function
Acute traumatic rib fractures are a common issue for patients of trauma surgeons. They inflict substantial morbidity, the most dreaded and consequential of which are pulmonary complications.
- Conditions
- Rib Fracture, Rib Fracture Multiple, Trauma, Trauma Chest
- Trial name
- RibFx (NCT03846024)
- Testing
- RibFx Orthosis Belt
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Vermont Medical Center
Rib Fractures, Spirometry
Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures
In patients admitted following a trauma, the incidence of multiple rib fractures is reported to be 9,7%, and this can be even higher in high energy trauma like motor vehicle accidents (1).
- Trial name
- NCT05105399
- Testing
- Serratus plane block (continuous or single-shot)
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Niguarda Hospital
Pain
Ultrasound-Guided Continuous Serratus Anterior Plane Block vs Dexmedetomidine Infusion in Patients With Rib Fractures.
The aim of this work is to compare analgesic efficacy in patients with multiple rib fractures who will be managed with Ultrasound-guided continuous serratus anterior plane block versus patients who will be managed with…
- Trial name
- NCT05965895
- Testing
- Ultrasound-guided continuous serratus anterior plane block, intravenous dexmedetomidine infusion
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Rib Fracture Multiple
A Prospective Randomized Controlled Study Comparing the Clinical Effects of Surgical and Non-surgical Treatment of Low Rib Fractures
The purpose of this study is to explore the difference between the clinical effects of surgical and non-surgical treatment for patients with low rib fracture, and to explore whether SSRF has more clinical treatment advantages in…
- Trial name
- NCT05758870
- Testing
- surgical stabilization of low rib fratures, converstive treatment of low rib fratures
- Volunteers
- 64 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Multiple Fracture Ribs
Prospective Comparative Study Between Ultrasound-guided Continuous Erector Spinae Plane Block and the Use of Intravenous Patient Controlled Analgesia for Management of Pain in Patients With Multiple Fracture Ribs
Rib fractures are common after blunt injury to the chest. Present in 10% of blunt trauma admissions. Pain associated with rib fractures can result in compromise of pulmonary function causing hypoxaemia or pneumonia, which may…
- Trial name
- NCT05975294
- Testing
- amixture 0.125% bupivicaine with fentanyl, 100 ml volume containing 80 mg of nalbuphine ,180 mg ketorolac, 24mg dexamethasone, 16 mg danset
- Volunteers
- 60 people
- Sponsor
- Sohag University
Erector Spinae Block, Edge of Laminar Block
Continuous Erector Spinae Block Versus Continuous Edge of Laminar Block on The Quality of Analgesia and Diaphragmatic Excursion in Patients With Multiple Rib Fractures
This prospective randomized clinical trial aims to compare the effect of continuous erector spinae plane block versus continuous edge of laminar block on the quality of analgesia and diaphragmatic excursion in patients with…
- Conditions
- Erector Spinae Block, Edge of Laminar Block, Analgesia, Diaphragmatic Excursion
- Trial name
- NCT07069101
- Testing
- Erector spinae block, Edge of lamina block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Chest Trauma, Chest Pain
Serratus Plane Block for Rib Fractures
Patients with ipsilateral multiple rib fractures will be randomized to receive either a single-shot ultrasound-guided serratus plane block, or a continuous serratus plane block within 24h from the chest trauma.
- Trial name
- NCT03664973
- Testing
- Serratus plane block
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Rib Fractures
Pain Relief for Ventilated Patients With Multiple Rib Fractures Using the ON-Q Pain Relief System
The purpose of this study is to find out if patients having the ON-Q post-op Pain Relief System for pain management of multiple rib fractures will require fewer ventilator days, and will need less IV pain medicine to control…
- Trial name
- ON-Q (NCT00880529)
- Testing
- ON-Q bupivicaine administration, IV opioid administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cooper Health System
Rib Fractures
Non-Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural in Pain Management of Rib Fractures
The purpose of this study is to compare 2 pain control treatments for people with 3 or more rib fractures.
- Trial name
- SUETHE-Ribs (NCT05069961)
- Testing
- ESPB, TEA
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University