Clinical trials: Multiple Sclerosis, MS
Multiple Sclerosis
Factors That Influence Compliance With Disease-Modifying Therapy in Multiple Sclerosis
The purpose of this study is to evaluate the coorelation between patient factors, health care provider factors, drug factors and compliance in patients with relapsing forms of multiple sclerosis (RMS) treated with Disease…
- Trial name
- NCT00223457
- Testing
- Factors that influence compliance
- Where
- United States
- Volunteers
- 1,040 people
- Sponsor
- University of Texas Southwestern Medical Center
Telerehabilitation, Multiple Sclerosis
Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis
Non-Inferiority Study, Post-Market Clinical Investigation with a Device, Single-Blind Randomized Controlled Trial in a Cohort of Patients Diagnosed with Multiple Sclerosis (MS).
- Conditions
- Telerehabilitation, Multiple Sclerosis, Cognitive Disorders, Neurorehabilitation
- Trial name
- NCT06964581
- Testing
- Cognitive treatment delivered via telerehabilitation., In-person cognitive treatment.
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Universita di Verona
Multiple Sclerosis
Reducing Sedentary Behaviour: A Novel Opportunity for Managing Comorbidity in MS?
Activity recommendations for the general population and those with multiple sclerosis (MS) focus on the promotion of activity that has a moderate intensity - in other words, activity intense enough to breathe heavily and sweat.
- Trial name
- NCT03136744
- Testing
- Sit Less with MS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Multiple Sclerosis
Fingolimod Real World Experience: the French Grand-Est Cohort
Objectives: This study describes efficacy and safety of Fingolimod in patients treated for at least 6 months in the east of France from January 2011 to December 2014.
- Trial name
- Gilenya (NCT02799199)
- Volunteers
- 1,014 people
- Sponsor
- CHU de Reims
Multiple Sclerosis
A Study to Evaluate the Impact of Using Warm Compress Prior to Daily Injections of Copaxone®
This study is designed to compare skin reactions with or without the use of warm compress prior to performing a Copaxone® injection.
- Trial name
- NCT00239993
- Testing
- glatiramer acetate, Warm compress prior to injection of glatiramer acetate
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Teva Neuroscience, Inc.
Sclerosis, Multiple, Neuromyelitis Optica Spectrum Disorder
French Registry for Monitoring Pregnancies for Multiple Sclerosis
The influence of pregnancy on the course of multiple sclerosis (MS) has long been a controversial topic. After the publication of the first large prospective study of pregnancy and MS in 1998, counselling of women with MS has…
- Conditions
- Sclerosis, Multiple, Neuromyelitis Optica Spectrum Disorder, Myelin Oligodendrocyte Glycoprotein (MOG)-Antibody Related Disorders, Pregnancy Abnormal
- Trial name
- RESPONSE (NCT03900221)
- Testing
- No intervention
- Where
- 48 sites in France, Martinique
- Volunteers
- 1,500 people
- Sponsor
- Hospices Civils de Lyon
Relapsing-Remitting Multiple Sclerosis (RRMS)
Brimonidine Tartrate for the Treatment of Injection Related Erythema
The primary objective of this study is to evaluate the Injection Related Erythema (IRE) mitigation effect of a single administration of brimonidine tartrate in comparison with a vehicle gel (placebo).
- Trial name
- BRITE (NCT02568111)
- Testing
- peginterferon beta-1a, brimonidine tartrate, Vehicle Gel
- Sponsor
- Biogen
Ehlers-Danlos Syndrome, Multiple Sclerosis
Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)
The investigators propose that evidence of chronic cerebrospinal venous insufficiency (CCSVI) may be evident in the vasculature of the fundus.
- Trial name
- NCT01356134
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Genetic Disease Investigators
Multiple Sclerosis
A Study Comparing Shared Solutions® Plus MS Center Support Versus Shared Solutions® Alone
To compare the effectiveness of a 90-day Copaxone® adherence enhancement program for a sample of MS patients who are at high risk of nonadherence and receive support from Shared Solutions® and their MS Center versus those who…
- Trial name
- NCT00240006
- Testing
- Shared Solutions® plus MS Center v. Shared Solutions®
- Volunteers
- 307 people
- Sponsor
- Teva Neuroscience, Inc.
Multiple Sclerosis
MR Perfusion Imaging and Hypercapnia (Increased Carbon Dioxide) to Study New Blood Vessel Formation in Multiple Sclerosis
This study will use magnetic resonance imaging (MRI) to examine and compare changes in blood flow and blood volume in the brains of normal volunteers and patients with multiple sclerosis (MS).
- Trial name
- NCT00064909
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Multiple Sclerosis
Multiple Sclerosis, Menstrual Cycle and Physical Acivity
This study aims to identify moderating variables that modify satisfaction with physical activity practice throughout the menstrual cycle (MC) in women with and without multiple sclerosis (MS) during High-Intensity Interval…
- Trial name
- EMMA (NCT06105463)
- Testing
- Strength training sessions and High-interval intensity training sessions
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Multiple Sclerosis, Radiologically Isolated Syndrome
Prognostic Value of Three New Biomarkers of Multiple Sclerosis in Patients With Radiologically Isolated Syndrome
To look at the prognostic value of new biomarkers in CSF and serum for characterisation of multiple sclerosis
- Trial name
- T-RIS (NCT03357887)
- Testing
- Analysis of cerebrospinal fluid and serum
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pediatric-Onset Multiple Sclerosis (POMS)
Dual-Task Training in Pediatric Multiple Sclerosis
This randomized controlled trial aims to investigate the effects of an 8-week dual-task exercise training program compared to conventional functional exercise training on motor and cognitive functions in adolescents with…
- Trial name
- DTT-POMS (NCT07571304)
- Testing
- Dual-Task Exercise Training, Conventional Functional Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istanbul University - Cerrahpasa
Multiple Sclerosis
Evaluate the Safe and Effective Use of the Avonex® Single-Use Autoinjector in Multiple Sclerosis Subjects
The primary objective of the study was to evaluate the safe and effective use of the single-use autoinjector for the intramuscular (IM) delivery of liquid Avonex® (interferon beta-1a) in participants with multiple sclerosis (MS).
- Trial name
- NCT00828204
- Testing
- single-use autoinjector with a prefilled liquid Avonex syringe, Avonex prefilled syringe via manual IM injection, BG9418 (interferon beta-1a)
- Where
- 16 sites in United States
- Volunteers
- 95 people
- Sponsor
- Biogen
Multiple Sclerosis
Kesimpta® (Ofatumumab) in Swiss Multiple Sclerosis Patients - an Observational Study
This is a multi-center, observational study carried out in Switzerland that aims to describe the effects of Ofatumumab in a setting of routine medical care.
- Trial name
- KOSMOS (NCT05285904)
- Testing
- Ofatumumab
- Where
- 13 sites in Switzerland
- Volunteers
- 107 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis
A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)
The primary objective of the study is to estimate the incidence rate of serious adverse events (SAEs), including but not limited to malignancies and serious and opportunistic infections, among participants with MS treated with…
- Trial name
- NCT05767736
- Testing
- Diroximel Fumarate, Dimethyl Fumarate, Disease-Modifying Therapies (DMTs)
- Where
- United States
- Volunteers
- 10,500 people
- Sponsor
- Biogen
Neuronal Plasticity, Multiple Sclerosis
Brain Activity Changes Following Neuroproprioceptive Physiotherapy in Multiple Sclerosis
Imaging methods bring new possibilities for describing the brain plasticity processes that underly the improvement of clinical function after physiotherapy in people with multiple sclerosis (pwMS).
- Conditions
- Neuronal Plasticity, Multiple Sclerosis, Rehabilitation
- Trial name
- NCT04448444
- Testing
- Motor Program Activating Therapy, Vojta reflex locomotion
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Multiple Sclerosis
Study of Utilization Patterns of Dimethyl Fumarate in Germany
The primary objective of this study is to estimate the proportion of DMF use that is prescribed "on-label" versus "off-label". The secondary objectives are: To describe the demographic characteristics and medical history of DMF…
- Trial name
- NCT02969304
- Testing
- dimethyl fumarate
- Where
- Germany
- Volunteers
- 930 people
- Sponsor
- Biogen
Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
Phase II Clinical Trial of OCH-NCNP1
This study is designed to assess the efficacy and safety of OCH-NCNP1 compared to placebo in subjects diagnosed with relapsing remitting multiple sclerosis (RRMS) and secondary progressive mltiple sclerosis (SPMS) .
- Trial name
- NCT04211740
- Testing
- OCH-NCNP1
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- National Center of Neurology and Psychiatry, Japan