Clinical trials: Multiple Sclerosis Fatigue
Multiple Sclerosis
Low Fat Diet for Fatigue in MS
A randomized, controlled pilot trial of a dietary intervention vs. wait-list control in patients with MS and fatigue for management of their fatigue.
- Trial name
- NCT03322982
- Testing
- Low-fat diet
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Fatigue and Sleep Quality in Multiple Sclerosis Patients
This study was planned to examine the effect of reiki application on fatigue and sleep quality in patients with multiple sclerosis.
- Trial name
- NCT05456464
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Sabahattin Zaim University
Multiple Sclerosis
Rehabilitation in Multiple Sclerosis - Sometimes Too Much?
The primary objective is to evaluate changes in fatigue and physical activity (step counts) before and after rehabilitation in patients with MS (EDSS 3-6.5).
- Trial name
- NCT03187847
- Testing
- Actigraph GT3X
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- Klinik Valens
Multiple Sclerosis
Efficacy of L-carnitine Versus Placebo in the Treatment of Fatigue in Multiple Sclerosis
The objective of this study is to evaluate the efficacy of L-carnitine versus placebo in the treatment of fatigue in multiple sclerosis patients. This study will randomize 60 patients in a cross-over design.
- Trial name
- FACTSEP (NCT01149525)
- Testing
- L-Carnitine
- Where
- 6 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Bordeaux
Multiple Sclerosis
Effectiveness of Home-Based Exercise and Brain Stimulation for Reducing Fatigue in Patients With Multiple Sclerosis
This randomized, double-blind, parallel-group clinical trial aims to assess the effectiveness of a combined intervention consisting of a home-based therapeutic exercise program and transcranial direct current stimulation (tDCS)…
- Trial name
- NCT07567989
- Testing
- Home-Based Therapeutic Exercise Program, Transcranial Direct Current Stimulation
- Where
- 3 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Jacobo Formigo
Multiple Sclerosis, Pilates Exercise
The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis
Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.
- Conditions
- Multiple Sclerosis, Pilates Exercise, Walking, Balance
- Trial name
- MS (NCT07504120)
- Testing
- Pilates
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Multiple Sclerosis
Propionic Acid in Multiple Sclerosis
The purpose of this study is to demonstrate the superiority of propionic acid over placebo as add on treatment in multiple sclerosis (MS).
- Trial name
- MADAI (NCT06402487)
- Testing
- Propionic acid 1000 mg capsule
- Where
- Austria
- Volunteers
- 101 people
- Sponsor
- Salzburger Landeskliniken
Multiple Sclerosis
Role of Neuromuscular Junction Function in Motor Fatigue in Multiple Sclerosis
This pilot study will evaluate for the presence of neuromuscular junction (NMJ) defect in women with motor fatigue in multiple sclerosis by Single Fiber Electromyography (SFEMG) using the concentric needle electrode.
- Trial name
- NCT02418897
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Multiple Sclerosis, Fatigue
Cubii for Exercise in People With MS
The goals of this observational study are to evaluate (1) the feasibility, usability, and satisfaction with the Cubii elliptical and (2) the preliminary efficacy of the Cubii elliptical for increasing activity (primary outcome)…
- Conditions
- Multiple Sclerosis, Fatigue, Activity, Motor, Quality of Life
- Trial name
- Cubii (NCT05826431)
- Testing
- Cubii elliptical
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Washington
Upper Motor Neuron Disease
Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients
To determine whether Spatially Distributed Sequential Functional Electrical Stimulation is more effective than Standard Electrical Stimulation During Functional Electrical Stimulation in Upper Motor Neuron Patients
- Trial name
- SDSS_UMS (NCT06421753)
- Testing
- SDSS, Standard Electrical Stimulation During Functional Electrical Stimulation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- UGECAM Rhône-Alpes
Multiple Sclerosis
Depression and Fatigue in MS Patients Treated With Betaferon.
This study aims to evaluate the occurence and severity of fatigue and depression in multiple sclerosis patients and the impact of Betaferon treatment on symptoms alterations.
- Trial name
- FADO (NCT01354665)
- Testing
- Interferon beta-1b (Betaferon, BAY86-5046)
- Where
- Poland
- Volunteers
- 567 people
- Sponsor
- Bayer
Primary Progressive Multiple Sclerosis, Exercise
The Influence of HIIT Versus MCT on Cardiorespiratory Fitness in PPMS
Endurance training revealed to be an effective means to increase cardiorespiratory fitness in persons with Multiple Sclerosis (MS), considered relevant to health-related quality of life in this population.
- Conditions
- Primary Progressive Multiple Sclerosis, Exercise, Cardiorespiratory Fitness
- Trial name
- CYPRO (NCT05229861)
- Testing
- HIIT, MCT
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- Klinik Valens
Multiple Sclerosis, Endurance
Comparison of Intermittent vs. Continuous Walking in MS
Objective: To compare effects of an intermittent and continuous walking program on walking endurance and fatigue in people with multiple sclerosis (MS).A randomized crossover prospective method was used.The intervention consisted…
- Trial name
- NCT02726373
- Testing
- type of walking
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Multiple Sclerosis
Effect of Hydrotherapy on Multiple Sclerosis
The purpose of this work was to investigate the effect of a hydrotherapy program on the balance and fatigue of patients with multiple sclerosis.
- Trial name
- NCT06121648
- Testing
- hydrotherapy, neurological physiotherapy
- Where
- Greece
- Volunteers
- 26 people
- Sponsor
- University of Thessaly
Multiple Sclerosis
Fampridine in MS Patients: A Cognition, Fatigue, Depression and Quality of Life Analysis
Fampyra, a voltage-dependent potassium channel blocker, is indicated for the improvement of walking in adult patients with multiple sclerosis with walking disability (EDSS 4-7).
- Trial name
- FAMILY (NCT03164018)
- Testing
- Fampridine
- Where
- Greece
- Volunteers
- 111 people
- Sponsor
- Genesis Pharma CNS & Specialty
Multiple Sclerosis, Long Covid
Fatigue Investigation Using Digital Outcomes
This study investigates objective methods to measure and monitor fatigue in patients with post-COVID-19 condition (long COVID) and multiple sclerosis (MS), and includes a group of healthy volunteers for comparison.
- Conditions
- Multiple Sclerosis, Long Covid, Healthy
- Trial name
- FIDO (NCT07783074)
- Where
- 6 sites in Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Liliana Barrios
Multiple Sclerosis, Fatigue
Sleep Medical Treatment in MS Patients Suffering From Fatigue
This study evaluates the effect of an extensive sleep medical investigation and of the subsequent treatment on multiple sclerosis (MS) related fatigue (provided a previously unknown sleep disorder was found).
- Trial name
- Sleep-in-MS (NCT03759249)
- Testing
- Sleep medical treatment
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- Charite University, Berlin, Germany
Multiple Sclerosis, Education
The Effects of Face-to-face and Tele-nursing Education on Fatigue, Pain, Sleep, and Urinary Tract Infections in Patients With Multiple Sclerosis.
The aim of this study is to evaluate the effects of face-to-face and distance nursing education, based on Pender's Health Promotion Model, on fatigue, pain, sleep, and urinary tract infections in MS patients who applied to the…
- Conditions
- Multiple Sclerosis, Education, Symptom Management
- Trial name
- NCT07411508
- Testing
- telenursing, face to face education, Control arm
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- ugurlu
Multiple Sclerosis
Teleconference Fatigue Management for People With Multiple Sclerosis
Approximately 60% of individuals with multiple sclerosis (MS) describe fatigue as their most disabling symptom. Energy conservation education involves teaching people with MS different strategies to manage fatigue and reduce its…
- Trial name
- NCT00591721
- Testing
- Energy conservation education
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Illinois Chicago
Multiple Sclerosis
Wahls Paleo Diet and Progressive Multiple Sclerosis
Based on favorable preliminary data from ongoing studies testing the safety and tolerability of a nutrition, exercise and neuromuscular electrical stimulation funded by Direct MS, the investigators are proposing a pilot study…
- Trial name
- NCT01915433
- Testing
- Wahls Paleo Plus, Wahls Diet
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Terry L. Wahls