Clinical trials: Multiple Trauma/Injuries
Ulcer Foot, Ulcer Healing
Aquacel With Strengthening Fiber (WSF) Ribbon Dressings
Retrospective, multi-site, non-comparative, post-market study
- Conditions
- Ulcer Foot, Ulcer Healing, Wound Infection
- Trial name
- NCT07308665
- Testing
- Aquacel Ribbon
- Volunteers
- 214 people
- Sponsor
- ConvaTec Inc.
Critical Illness, Hyperglycemia
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients
Critically ill patients admitted to intensive care units (ICUs) frequently develop elevated blood sugar levels (hyperglycemia) as a result of acute illness-related stress, even if they do not have diabetes.
- Conditions
- Critical Illness, Hyperglycemia, Acute Kidney Injury, Multiple Organ Failure
- Trial name
- NCT07853911
- Volunteers
- 230 people
- Sponsor
- Assiut University
Sepsis, Burn Injury
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07249762
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Acute Kidney Injury
A Multi-Center Study of a SCD for Immunomodulatory Dysregulation in Pediatric AKI
The SCD PED-02 trial is examining the safety and efficacy of the Selective Cytopheretic Device (SCD) in treating pediatric acute kidney injury (AKI).
- Trial name
- SCD PED-02 (NCT04869787)
- Testing
- Selective Cytopheretic Device
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Multiple Trauma, Head Trauma
Oxepa in Multiple Trauma
This is a single-center, prospective, randomized, comparative, double-blind controlled clinical study mend to assess the effect of enteral feeding with Oxepa (a fish oil-based nutrition), compared to an isocaloric control, on…
- Trial name
- OMT (NCT01099501)
- Testing
- Oxepa (enteral nutrition formula, ABBOTT), at a dose determined by a patient's energy expenditure and tolerance of enteral feeding., oxepa, Control group
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Rabin Medical Center
Perinatal Depression, COVID19
Global Mental Health of Urban Mothers
Mental health disorders are common during pregnancy and the postnatal period, and can have serious adverse effects on the well-being of woman and child.
- Conditions
- Perinatal Depression, COVID19, Anxiety, PTSD
- Trial name
- MUM (NCT04363177)
- Testing
- Web-based psychosocial peer-to-peer support
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Spinal Cord Injuries, Multiple Sclerosis
Polish Translation and Validation of NBSS, Qualiveen and SF-Qualiveen
The aim of this study is to translate, culturally adapt, and validate Polish versions of the NBSS, Qualiveen and SF-Qualiveen questionnaires.
- Trial name
- NCT04185792
- Testing
- NBSS, Qualiveen and SF-Qualiveen
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Lateral Epicondylitis
Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia
The purpose of this research is to compare two different approaches for treating patients with lateral epicondylalgia: electric dry needling, thrust manipulation and stretching versus impairment-based manual therapy, exercise and…
- Trial name
- NCT03167710
- Testing
- Dry Needling, manipulation, stretching, manual therapy, exercise, ultrasound
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Bronchopulmonary Dysplasia (BPD), ELGAN (22-28SA)
Mesenchymal Stromal Cell Therapy to Prevent Bronchopulmonary Dysplasia in Extreme Preterm Infants
This clinical trial aims to evaluate the safety and efficacy of mesenchymal stromal cell (MSC) therapy in extreme preterm infants to prevent bronchopulmonary dysplasia, the main respiratory complication of preterm birth.
- Trial name
- HULC-2 (NCT07058025)
- Testing
- Human Allogenic Umbilical Cord Mesenchymal Stromal Cells
- Where
- 8 sites in Canada
- Volunteers
- 168 people
- Sponsor
- Ottawa Hospital Research Institute
TBI (Traumatic Brain Injury) or MS (Multiple Sclerosis)
Improving Learning in Hispanics With TBI or MS
The goal of this study is to establish that a memory retraining protocol, originally developed for English-speakers, and translated into Spanish, is effective.
- Trial name
- NCT03453125
- Testing
- Spanish modified Story Memory Technique (mSMT)
- Where
- 2 sites in United States, Spain
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
ReInventing Yourself After SCI: an Intervention to Improve Outcomes After Spinal Cord Injury
The primary goal of this study is to conduct a multi-site RCT to evaluate the replicability and efficacy of the ReInventing Yourself after SCI intervention in improving health and function outcomes for persons with spinal cord…
- Trial name
- NCT03390140
- Testing
- ReInventing Yourself after SCI structured group CBT, ReInventing Yourself after SCI study-specific workbook, ReInventing Yourself after SCI YouTube videos
- Where
- 3 sites in United States
- Volunteers
- 281 people
- Sponsor
- Craig Hospital
Severe Sepsis, Septic Shock
Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury
Severe sepsis or septic shock with acute kidney injury shows high mortality in intensive care unit. A few studies have shown CRRT relating the clinical improvement seems to be related to the early initiation of therapy.
- Conditions
- Severe Sepsis, Septic Shock, Acute Kidney Injury
- Trial name
- NCT00837057
- Testing
- crrt
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Cardiac Arrest (CA), Post Cardiac Arrest Syndrome
TNF-α Antagonists Mitigate Systemic Inflammatory Response After Cardiac Arrest.
The investigators assessed the effect of TNF-α antagonism within 6 hours of return of spontaneous circulation on 30-day mortality in patients who remained comatose after cardiopulmonary resuscitation (CPR) following cardiac…
- Trial name
- NCT07176754
- Testing
- Infliximab
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Peking University Third Hospital
Multiple Trauma
Independent Predictors of Mortality in Polytrauma Patients
Prospective observational trial searching for independent predictors of mortality. Data was collected at trauma scene, ER, three and 24 hours of hospital stay.The patients will be followed for 30 days after hospital admission.
- Trial name
- NCT01669577
- Testing
- analysis of blood samples and clinical features
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Muscular Diseases
The Role of Ischaemia-reperfusion Injury in the Pathogenesis of Muscle Wasting After Thoracic Aortic Surgery
Single-centre observational study over one year investigating the mechanisms of muscle homeostasis in patients with acute skeletal muscle atrophy following major aortic surgery
- Trial name
- RIMMAS (NCT03354767)
- Testing
- Aortic and aortic valve surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs in DCD Kidney Transplantation
This study is designed to determine the efficacy and safety of allogeneic bone marrow-derived mesenchymal stem cells in kidney transplantation from Chinese donation after citizen's death (DCD).
- Trial name
- NCT02561767
- Testing
- bone marrow-derived mesenchymal stem cells, Saline, Induction therapy (ATG or Basiliximab)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Stroke, Traumatic Brain Injury
Hypnosis and Attention in Patients With a Neurological Disease (Stroke, Traumatic Brain Injury and Multiple Sclerosis)
This feasibility study investigates the potential of hypnosis as a complementary therapy for improving attentional deficits and reducing fatigue in patients with neurological conditions such as stroke, traumatic brain injury…
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis
- Trial name
- HYPNOVA (NCT07256704)
- Testing
- Intervention Hypnosis
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Luzerner Kantonsspital
Open Abdomen
Post Market Clinical Follow Up Study of Avance Foam Abdominal Dressing Kit in Open Abdomen
The investigation is a Post Marketing Follow-Up Study for the Avance Foam Abdominal Dressing Kit conducted as part of Mölnlycke Health Care's quality system.
- Trial name
- NCT01968811
- Testing
- Avance Foam dressing kit
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Molnlycke Health Care AB
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