Clinical trials: Multiple Trauma/Injuries
Covid19
COVID-19 Soliris Expanded Access Protocol
This protocol provides participants with COVID-19 access to Soliris.
- Trial name
- NCT04802083
- Testing
- Eculizumab
- Sponsor
- Alexion Pharmaceuticals, Inc.
Soft Tissue Injury
A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.
Researchers are looking for a different way to treat people who have an injury to their muscles, ligaments, or tendons in their legs or feet. This is known as a "soft tissue" injury.
- Trial name
- NCT05026320
- Testing
- Naproxen gel, Diclofenac gel
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- Bayer
Contusions
Phase III Trial to Assess the Safety and Efficacy of TK-254RX in Patients With Contusions
This study is an open-label, multi-centric clinical trial to evaluate the safety and efficacy of TK-254RX in patients with contusions. The primary objective of this study is to assess the safety of TK-254RX.
- Trial name
- NCT06871046
- Testing
- Esflurbiprofen Topical System (EFTS)
- Where
- 5 sites in Germany
- Volunteers
- 221 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Musculoskeletal Injury, Hypogonadism
Adaptions and Resiliency to Multi-Stressor OpeRations
Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits.
- Conditions
- Musculoskeletal Injury, Hypogonadism, Hormonal Contraception
- Trial name
- ARMOR (NCT06455969)
- Testing
- Goserelin 3.6 MG, Multi-Stressor Training, Testosterone gel (AndroGel 5g)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bradley Nindl
Spinal Cord Injuries (SCI)
AI-Guided Multi-Electrode Transcutaneous Spinal Cord Stimulation for Gait Rehabilitation in People With Spinal Cord Injury or Stroke
The goal of this clinical trial is to investigate whether personalized multi-electrode transcutaneous spinal cord stimulation (tSCS), guided by machine learning (ML) and combined with gait training, can improve walking function…
- Trial name
- NCT07895888
- Testing
- Single-Electrode Tonic tSCS, Multi-Electrode Spatiotemporal tSCS
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo General Hospital
Trauma Injury of Hand Multiple, Neurologic Disorder
Arm Use With Soft-robotic Glove
This study, aimed at investigating the impact of using a supportive soft-robotic glove on actual arm and hand use in daily life, is designed as a single-case experimental design study.
- Trial name
- NCT06033027
- Testing
- Carbonhand
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Roessingh Research and Development
Free Fall Trauma
Mortality in Free-fall Trauma Patients
In this study, the investigators aimed to analyze the demographic characteristics, patterns of injury, and mortality after free fall in the emergency department of the National Taiwan University Hospital, and the affiliations…
- Trial name
- NCT04596436
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Intracranial Aneurysm, Pipeline Embolization Device
Post Market Multi-Center Retrospective Research on Embolization of Intracranial Aneurysms With Pipeline Embolization Device in China
Pipeline TM embolization device launched to China in 2014, and has been widely used to treat large width IA. Therefore, it is necessary to collect and analysis the clinical data to evaluate effectiveness and safety of its usage…
- Trial name
- PLUS (NCT03831672)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Neurosurgical Institute
Neurologic Disorder, Stroke
Home Based Tele-exercise for People With Chronic Neurological Impairments
To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health and wellness in people with chronic neurological impairments (CNI).
- Conditions
- Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- Telex (NCT04564495)
- Testing
- Seated exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Burke Medical Research Institute
Whiplash Injuries, Sedentary Lifestyle
A Novel Intervention to Promote Engagement in Physical Activity for Individuals With Whiplash Associated Disorder
Approximately 50% of adults who have a whiplash injury experience ongoing pain and disability from whiplash associated disorder (WAD). Causes are multifactorial, with considerable variation.
- Trial name
- NCT03729856
- Testing
- intervention, B, Follow-up
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- The University of Queensland
Surgical Wound
VASCADE ANTEGRADE-PVD Post-Market Registry
The objective of the registry is to collect procedural outcomes data when the Cardiva VASCADE Vascular Closure System (VCS) is used to seal femoral arterial access sites at the completion of ipsilateral peripheral interventional…
- Trial name
- NCT02948257
- Testing
- Cardiva Medical VASCADE VCS
- Where
- 5 sites in United States
- Volunteers
- 52 people
- Sponsor
- Cardiva Medical, Inc.
Wound
A Study Evaluating the Safety and Efficacy of the 3M™ V.A.C. Peel and Place Dressing
The purpose of this clinical study is to obtain post-market safety and efficacy data when the V.A.C.® Peel and Place dressing is used in conjunction with 3M™ V.A.C.® Therapy.
- Trial name
- NCT06625385
- Testing
- 3M™ V.A.C.® Peel and Place Dressing
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Moderate Traumatic Brain Injury
Intracranial Pressure Monitoring in Moderate Traumatic Brain Injury
Objectives The primary focus for scientific investigation is to conduct a multi-center observational study to determine if intracranial pressure (ICP) monitoring to direct treatment of patients with moderate traumatic brain…
- Trial name
- IPMMTBI (NCT04900168)
- Testing
- Intracranial pressure monitoring
- Where
- China
- Volunteers
- 832 people
- Sponsor
- Tang-Du Hospital
Epilepsy, Brain Injuries
Hybrid Device DIALYTRODE for Multimodal Neuro-monitoring of Patients With Brain Injury and Status Epilepticus
This clinical trial evaluates the safety and diagnostic performance of a newly developed combined catheter that will be implanted into the brain of patients with severe brain injury for short time (up to 28 days) monitoring of…
- Trial name
- NCT03163485
- Testing
- Dialytrode, Standard treatment
- Where
- 2 sites in Germany
- Sponsor
- University of Erlangen-Nürnberg Medical School
Rib; Fracture, Multiple, With Flail Chest
Prospective Follow up of Minimally Invasive Chest Wall Surgery After Trauma
The purpose of this study is to assess the outcome of a muscle sparing, minimally invasive open surgical technique for unstable ribcage injuries after trauma.
- Trial name
- NCT04710602
- Testing
- Minimally invasive surgical fixation of unstable rib cage, Large incision surgical fixation of unstable rib cage.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Postconcussion Syndrome, Mild Traumatic Brain Injury
Effectiveness of Rehabilitation in Adults Suffering From Persistent Concussion Symptoms
Protocol Summary The present study was developed to better understand the effects and benefits of individualizing rehabilitative treatments based on subgroup classifications determined by a standardized clinical examination.
- Trial name
- NCT06069700
- Testing
- Non-pharmacological Individualized rehabilitative therapy, Non-pharmacological Usual care therapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
White Matter Abnormalities, Nonspecific, ADHD
Predicting the Outcome of ADHD in White Matter Injure Neonates With Multi-modality MRI
The goal of this bidirectional observational cohort study is to investigate the longitudinal relationship between neonatal white matter injury (WMI) and the subsequent development of attention-deficit/hyperactivity disorder…
- Conditions
- White Matter Abnormalities, Nonspecific, ADHD, Neurodevelopment Outcome
- Trial name
- NCT07836244
- Where
- 9 sites in China
- Volunteers
- 348 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Rib Fractures, Polytrauma
Blunt Thoracic Trauma: Definition of a Standard Operating Procedure
Rib fractures are the most frequent injury after blunt thoracic trauma. It is very important to choose the most appropriate interventions to prevent complications.
- Conditions
- Rib Fractures, Polytrauma, Thoracic Injury, Respiratory Failure
- Trial name
- NCT05617404
- Testing
- CT scan
- Where
- Spain
- Volunteers
- 553 people
- Sponsor
- Corporacion Parc Tauli
Traumatic Brain Injury, Posttraumatic Stress Disorders
Telepharmacy Robotic Medicine Delivery Unit "TRMDU" Assessment
The objective of this study is to evaluate whether use of TRMDU in addition to medication review leads to improved outcomes and reduced health care costs for patients when compared with medication review alone.
- Conditions
- Traumatic Brain Injury, Posttraumatic Stress Disorders, Trauma, Combat Disorders
- Trial name
- NCT01007006
- Testing
- TMRDU
- Where
- 3 sites in United States
- Sponsor
- University of Illinois Chicago
Palmaris Longus Muscle, Absence of, Carpal Tunnel Syndrome
Electrophysiological Changes Based on the Palmaris Longus
One of the most important causes of carpal tunnel syndrome is increased pressure in the canal. With the loading of the palmaris longus at 20 degrees of wrist extension, the pressure within the canal increases more than the load…
- Conditions
- Palmaris Longus Muscle, Absence of, Carpal Tunnel Syndrome, EMG Syndrome
- Trial name
- NCT04619849
- Testing
- EMG, Palmaris Longus Test
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
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