Clinical trials: Muscle Damage
Muscle Damage
Water Oxygenation and Brain Activity
The primary purpose of this interventional, placebo controlled, crossover, double blind, basic science exploratory study is to investigate whether there is a difference in brain electrophysiological oscillatory activity in…
- Trial name
- NCT02688452
- Testing
- Electrokinetically modified water (EMW)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Muscle Damage
Effect of Compression Garments on Exercise Performance Following Acute High Intensity Exercise
To examine the influence of compression garments manufactured with Far-Infrared technology on exercise performance during and after repeated eccentric isokinetic muscle actions of the leg extensors.
- Trial name
- NCT02076334
- Testing
- Far Infrared Fabric, Spandex
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Exercise-induced Muscle Damage, Movement Disorders
Neurodynamic Mobilization and Foam Rolling
The purpose of this study was to assess the acute effects of a single NM treatment session on DOMS and to compare them with those of one foam roller (FR) session.
- Conditions
- Exercise-induced Muscle Damage, Movement Disorders, Nerve Pain
- Trial name
- NCT03160937
- Testing
- Manual therapy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Muscle Damage
The Effect of Nutritional Interventions on Exercise-induced Muscle Damage
The study is a randomized, double-blinded, placebo-controlled trial that will include the participation of 69 women, aged 18-40 years.
- Trial name
- NCT02839525
- Testing
- Omega 3, Isolate whey protein, Omega 3 and Isolate whey protein
- Where
- Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Skeletal Muscle Damage, Aseptic Inflammation
Redox Status and Immune Function
In this investigation the investigators utilized N-acetylcysteine (NAC) supplementation to enhance reduced glutathione (GSH) stores during an 8-day recovery period from a strenuous eccentric exercise protocol in order to test the…
- Conditions
- Skeletal Muscle Damage, Aseptic Inflammation, Skeletal Muscle Function
- Trial name
- NCT02930031
- Testing
- n-acetylcysteine
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Protein Supplementation and Skeletal Muscle Healing Process
In this study the investigators utilized protein supplementation over an 8-day period following eccentric exercise-induced muscle damage in order to test the initial hypotheses : i) protein supplementation after exercise-induced…
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Skeletal Muscle Performance, Intracellular Signaling in Skeletal Muscle
- Trial name
- NCT02816411
- Testing
- Milk protein isolate
- Where
- Greece
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Muscle Damage
Effect of American Ginseng on Exercise-induced Muscle Soreness
Healthy participants will ingest American ginseng daily or a placebo for four weeks prior to engaging in a unaccustomed exercise bout designed to induce mild-moderate muscle soreness.
- Trial name
- NCT01827696
- Testing
- Ginseng
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Muscle Damage
Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage
Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years.
- Trial name
- NCT02493556
- Testing
- LLLT before muscle damage, LLLT after muscle damage
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Muscle Injury, Muscle Soreness
Effects of Wobenzym® Plus in Healthy, Sportive People After Eccentric Exercise
The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and…
- Conditions
- Muscle Injury, Muscle Soreness, Exercise Induced Muscle Damage
- Trial name
- 2012-005003-40 (NCT01845558)
- Testing
- Wobenzym® plus
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mucos Pharma GmbH & Co. KG
Muscle Damage, Oxidative Stress
Iron Supplementation and Eccentric Exercise
Iron supplementation is very common in athletes, probably due to its catalytic role on the oxygen transport and optimal function of oxidative enzymes and proteins during exercise.
- Trial name
- NCT02374619
- Testing
- Iron supplement Resoferon Ferrous Sulfate
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Muscle Damage
Investigating Muscle Repair in Response to Icing Therapy Post Eccentric Muscle Damage Exercise
The purpose of our research is to investigate the effects of applying cold therapy, or "icing," to injured muscles in terms of strength recovery and muscle soreness amelioration following unaccustomed exercise.
- Trial name
- NCT02280668
- Testing
- Icing Therapy, the eccentric muscle damage exercise
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Exercise-induced Muscle Damage
The Effect of Ischemic Pre-Conditioning on the Rate of Recovery Following Exercise-Induced Muscle Damage
Strenuous exercise or exercise involving eccentric muscle contractions can lead to muscle damage and changes in muscle function; this is known as exercise-induced muscle damage (EIMD).
- Trial name
- NCT01907841
- Testing
- Ischemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Muscle Damage
Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness
Study Objectives 1. Compare beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) to cold water immersion on performance recovery from an acute bout of high intensity resistance exercise. 2.
- Trial name
- NCT01793779
- Testing
- cold water immersion, beta-hydroxy-beta-methylbutyrate free acid (HMB-FA)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Skeletal Muscle Damage, Skeletal Muscle Performance
NAC Supplementation and Skeletal Muscle Performance
In this investigation the investigators utilized NAC administration to foster GSH availability during an 8-day period following eccentric exercise-induced muscle damage in order to test our hypotheses: i) antioxidant…
- Conditions
- Skeletal Muscle Damage, Skeletal Muscle Performance, Intgracellular Signaling in Skeletal Muscle, Inflammatory Status
- Trial name
- NCT01778309
- Testing
- n-acetylcysteine supplementation
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Muscle Damage, Inflammation
Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise
The aim of this study is to assess the effect of ingesting a commercial carbohydrate and protein dietary supplement in powder form (P-CHO supplement) or a milk shake with skimmed milk, strawberries and banana (MS), after…
- Conditions
- Muscle Damage, Inflammation, Oxidative Stress, Functional Recovery
- Trial name
- NCT01555775
- Testing
- P-CHO supplement, Fruit Milk Shake
- Where
- Portugal
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Aging, Muscle Damage
Eccentric Exercise and Oxidative Stress
The purpose of the present investigation is to compare the responses and adaptations of young and elderly individuals to repeated eccentric exercise in regards to muscle function and redox homeostasis in a side-by-side comparison.
- Conditions
- Aging, Muscle Damage, Oxidative Stress
- Trial name
- NCT01728675
- Testing
- Exercise
- Where
- Cyprus
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- European University Cyprus
Muscle Damage, Muscle Inflammation
The Effects of High Dose Fish Oil Supplementation on Delayed Onset Muscle Soreness and Inflammatory Markers
The purpose of this study is to determine the effects of fish oil supplementation (Lovaza, GlaxoSmithKline) on muscle strength, muscle soreness and inflammation following exercise.
- Trial name
- NCT00805870
- Testing
- Lovaza (omega-3-acid ethyl esters), Wheat Germ Oil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Michigan University
Exercise-induced Muscle Damage
Exercise-induced Muscle Damage is Reduced in Resistance Trained Athletes by Branch Chain Amino Acids
It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and causes severe soreness and discomfort.
- Trial name
- NCT01529281
- Testing
- Branch Chain Amino Acid (BCAA)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Muscle Damage, Inflammation
Branched-chain Amino Acids Supplementation and Resistance Exercise-induced Muscle Damage and Inflammation
This study aims to evaluate the effects of branched-chain amino acids (BCAA) supplementation on resistance exercise-induced muscle damage and inflammation.
- Trial name
- NCT01305018
- Testing
- BCAA, Leucine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo