Clinical trials: Muscle Disorders
Congenital Heart Disease, Single Ventricle
Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training
Introduction: The Fontan operation is the surgical treatment in most patients with either anatomic or functional single ventricles.
- Conditions
- Congenital Heart Disease, Single Ventricle, Univentricular Heart
- Trial name
- NCT02283255
- Testing
- Aerobic Exercise Training, Inspiratory Muscle Training, No Exercise Training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Fibromyalgia
The Effect of Perception of Improvement in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by impaired perception, transmission, and processing of nociceptive stimuli and causing widespread pain.
- Trial name
- NCT06508385
- Testing
- Breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Medeniyet University
Fibromyalgia
Effect of Suboccipital Release in Patients With Fibromyalgia Syndrome
This study was designed to examine the efficacy of suboccipital release in Patients With FMS and to provide preliminary evidence regarding its effects on pain and QOL by objectively measuring Cortisol level in FMS patien
- Trial name
- NCT06879743
- Testing
- Suboccipital release
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Muscle Fatigue, Trapezius Muscle Strain
Short Interventions to Prevent Trapezius Muscle Fatigue in Computer Work
This study is expected to demonstrate that during experimental days of seated computer work sustained and focalized low-level muscle activity contributes to the development of long-lasting fatigue effects (and thus possible…
- Trial name
- NCT03863340
- Testing
- interruptions of work tasks
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
COPD
Inspiratory Muscle Training on Respiratory Muscle Function，Quality of Life and Exercise Capacity in Stable COPD
Comparable RCTs of clinical therapeutic effects using respiratory physiology-oriented IMT device in different operation principle in COPD are so far lacking.
- Trial name
- NCT03101774
- Testing
- Threshold inspiratory muscle training, Resistive inspiratory muscle training, Control group
- Volunteers
- 60 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Premenstrual Syndrome
Progressive Muscle Relaxation and Kinesio Taping for Premenstrual Syndrome
This randomized controlled trial evaluated the effects of progressive muscle relaxation exercise, kinesio taping, and their combined application on premenstrual symptoms, perceived stress, severity of depressive symptoms, and…
- Trial name
- NCT07791121
- Testing
- Progressive Muscle Relaxation Exercise, Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people
- Sponsor
- ASLI ER KORUCU
Peripheral Arterial Disease, Diabetes Mellitus
SPECT/CT Imaging of Skeletal Muscle Perfusion
This study will use SPECT/CT imaging to assess the effect of percutaneous revascularization treatments in patients with Peripheral arterial disease and diabetes mellitus, in whom the disease can progress more quickly than in…
- Trial name
- NCT02791204
- Testing
- SPECT/CT imaging following revascularization procedures, SPECT/CT imaging
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yale University
Type 2 Diabetes, Heart Failure
Optimized Glycemic Control in Heart Failure Patients With DM2:"Effect on Left Ventricular Function and Skeletal Muscle"
The investigators wish to investigate wether a more strict diabetic control improves cardiac function, muscle strength, exercise capacity and decreases symptoms.
- Trial name
- HFDM (NCT01213784)
- Testing
- all antidiabetic drugs will be appliable
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Patellofemoral Osteoarthritis
Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study
The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap).
- Trial name
- NCT02825238
- Testing
- Supervised exercise program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Sarcopenia, Sarcopenic Obesity
Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults
Syndromes such as sarcopenia, sarcopenic obesity and osteosarcopenic obesity are commonly seen in older adults. They result from the impairment of muscle, bone and adipose tissue.
- Conditions
- Sarcopenia, Sarcopenic Obesity, Osteopenia, Osteoporosis
- Trial name
- NCT04122638
- Where
- Turkey (Türkiye)
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Goztepe Training and Research Hospital
Fibromyalgia, Chronic Pain
Assessment of Posture, Balance, Gait Disorders in Patients With Fibromyalgia
The study aims to determine the posture, balance and gait disorders objectively in patients with fibromyalgia (FM) and to investigate their relationships with disease-related parameters.
- Trial name
- NCT06245226
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Fatigue Syndrome, Chronic
Fatigue in Air Search and Rescue Missions
The purpose of this observational study is to understand and evaluate the physiological, psychological, and cognitive impact of 15 consecutive days of air search and rescue mission deployments on Portuguese Air Force crews.
- Trial name
- NCT06253026
- Testing
- Search and rescue mission
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Stress Urinary Incontinence, Athletes
Measurement of Intravaginal and Intra-abdominal Pressure and Pad Test During Sports Activities (SPORTVAGPRES)
To compare the impact of selected physical activities on pelvic floor and stress urinary incontinence in sportwoman.
- Trial name
- SPORTVAGPRES (NCT06224335)
- Testing
- intra-abdominal pressure with Femfit® device during (jumps on the ground, jumps on a trampoline, weightlifting, slow running, fast running
- Where
- Slovakia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Comenius University
Facioscapulohumeral Muscular Dystrophy, Facioscapulohumeral Muscular Dystrophy 1
Ultrasound Detection of Early Facial Muscle Changes in FSHD: Thickness and Echo Intensity Findings
Facioscapulohumeral muscular dystrophy (FSHD) is characterized by early and significant involvement of facial muscles; however, objective imaging data focusing on facial muscles are limited.
- Conditions
- Facioscapulohumeral Muscular Dystrophy, Facioscapulohumeral Muscular Dystrophy 1, Neuromuscular Disease
- Trial name
- FACIAL-FSHD (NCT07331025)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Koç University
Muscle Weakness, Osteoporosis, Postmenopausal
Assessing the Effect of Shatavari Supplementation on Bone and Skeletal Muscle Health in Healthy Postmenopausal Women
Shatavari is a plant that grows in Nepal, Sri Lanka, India and the Himalayas and its root has long been used in Ayurvedic medicine.
- Trial name
- NCT05025917
- Testing
- Shatavari, Magnesium stearate
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Muscle Cramps, Cirrhosis
Safety and Efficacy of Baclofen for Treatment of Muscle Spasms in Patients With Cirrhosis: A Pilot Study
The purpose of this study is to determine the safety and efficacy of the medication Baclofen for treatment of muscle cramps in patients with cirrhosis.
- Trial name
- NCT02298868
- Testing
- Baclofen
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Spinal Muscular Atrophy
Outpatient Rehabilitation Intervention for Young Children With SMA
An outpatient rehabilitation program for children (6 months to less than 6 years old) with Spinal Muscular Atrophy (SMA) treated with genetic based therapies is being studied.
- Trial name
- NCT05638750
- Testing
- Rehabilitation Intervention
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Myotonic Dystrophy 1
Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1
The primary purpose of the study is to evaluate the safety and tolerability of single intravenous (IV) doses of PGN-EDODM1 administered to participants with Myotonic Dystrophy Type 1 (DM1).
- Trial name
- FREEDOM-DM1 (NCT06204809)
- Testing
- PGN-EDODM1 for infusion
- Where
- 12 sites in United States, Canada and 1 more
- Volunteers
- 24 people
- Sponsor
- PepGen Inc
Shoulder Pain
PREVALENCE OF SCAPULAR DYSKINESIS
Objective: This study will aim to determine the prevalence of scapular dyskinesis (SD) among Egyptian physical therapy practitioners and will explore associated epidemiological factors, including age, sex, BMI, shoulder and neck…
- Trial name
- NCT07123532
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Cairo University
Obstructive Sleep Apnea, Oxidative Stress
Effect of EMST Systemic Inflammation and Oxidative Stress in Patients With Moderate OSAS
It was aimed to investigate the effect of expiratory muscle strength training (EMST) applied at different intensities on systemic inflammation and oxidative stress in patients with moderate obstructive sleep apnea syndrome…
- Conditions
- Obstructive Sleep Apnea, Oxidative Stress, Respiratory Muscle Training
- Trial name
- NCT05242406
- Testing
- Expiratory muscle trainig
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital
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