Clinical trials: Muscle Disorders
Stroke, Spasticity, Muscle
Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.
- Conditions
- Stroke, Spasticity, Muscle, Muscle Fatigue, Gait, Hemiplegic
- Trial name
- COCON (NCT03342820)
- Testing
- Muscle fatigue
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
COVID-19, Genetic Predisposition to Disease
Physiotherapy for Persistent COVID-19 Disease Using Aerobic Exercise
Aerobic exercise - Nordic walking in Persistent Covid (PC) vs. healthy controls. The main objective of this study is to analyse the genes associated with increased physical performance in patients with PC vs.
- Trial name
- NCT05453188
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Piriformis Syndrome
Comparison of Laser and Shockwave Therapy for Piriformis Syndrome With Adjunctive Exercise
This study is a prospective randomized controlled trial comparing the effectiveness of low-level laser therapy combined with exercise versus radial extracorporeal shockwave therapy combined with exercise in patients with…
- Trial name
- LASWEX-PS (NCT07567703)
- Testing
- Low-Level Laser Therapy + Therapeutic Exercise, Radial Shockwave Therapy + Therapeutic Exercise
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Stroke
Validation of a Spasticity Measurement Tool
The objective of this project is to investigate the validity of a handheld spasticity measurement tool against standard clinical measurements of spasticity.
- Trial name
- NCT05374174
- Testing
- Tardieu Scale for Spasticity
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Muscle Wasting
Effects of Functional Electrical Stimulation in Patients Undergoing Coronary Artery Bypass Grafting Surgery
Even with major advances in clinical therapy and percutaneous interventions, coronary artery bypass grafting (CABG) is the most common cardiac surgery performed worldwide and is an effective treatment in reducing symptoms and…
- Trial name
- NCT03560713
- Testing
- Functional Electrical Stimulation (FES)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Santa Maria
Soft Tissue Mobilisation, Vestibular Exercises
Temporomandibular Joint and Soft Tissue Mobilisation Techniques on Bening Paroxymal Vertigo
The purpose of this study was to investigated effectiveness of temporamandibular joint and soft tissue mobilization on patients with Benign Paroxysmal Positional Vertigo (BPPV).
- Conditions
- Soft Tissue Mobilisation, Vestibular Exercises, Physiotherapy, Vertigo, Paroxysmal
- Trial name
- NCT05944159
- Testing
- Study Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Alanya Alaaddin Keykubat University
Fibromyalgia, D Vitamin Deficiency
Valuation of Efficacy and Safety of Vitamin D3 Use in 80 Women Diagnosed With Fibromyalgia. Using FIQ Score and VAS.
Fibromyalgia is a disease that significantly decreases the quality of life of people who suffer from it, has great repercussions at the socio-economic level due to the incapacity it produces.
- Trial name
- NCT03369379
- Testing
- D3 Vitamin
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Chronic Fatigue Syndrome
Guanidinoacetic Acid Loading for Chronic Fatigue Syndrome
Chronic fatigue syndrome (CFS) is a debilitating condition of unknown etiology. Recent studies have shown that CFS is associated with impaired cellular energetics and low levels of phosphocreatine.
- Trial name
- NCT02213679
- Testing
- Guanidinoacetic acid
- Where
- Serbia
- Volunteers
- 20 people
- Sponsor
- Center for Health Sciences, Serbia
Vitamin D Deficiency, Sarcopenia
Effect of Vitamin D3 Supplementation on Muscle Mass in ICU Patient
A randomized double blind placebo control trial study will be conducted in critically ill patients with vitamin D deficiency. Investigator aimed to study the effect of oral vitamin D3 supplementation, compare to placebo, on…
- Conditions
- Vitamin D Deficiency, Sarcopenia, Critical Illness
- Trial name
- NCT02594579
- Testing
- Vitamin D3
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Neuromuscular Diseases in Children, Cerebral Palsy, Spastic
Muscle Spasticity Reduction in Children With Cerebral Palsy by Means of Hippotherapy
The aim of this study is to evaluate if a intervention with hippotherapy will improve spasticity for children ages 3-14 who have cerebral palsy.
- Conditions
- Neuromuscular Diseases in Children, Cerebral Palsy, Spastic, Spasticity, Muscle
- Trial name
- NCT03212846
- Testing
- Hippotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Cadiz
Fibromyalgia
THE EFFECT OF CHIROPRACTIC THORACIC MANIPULATION ON PAIN, DEPRESSION, SLEEP AND QUALITY OF LIFE IN PATIENTS WITH FIBROMYALGIA
This study aimed to investigate the effects of thoracic chiropractic manipulations on pain intensity, depression levels, sleep, and quality of life in women diagnosed with fibromyalgia.
- Trial name
- NCT06194942
- Testing
- chiropractic manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Stroke, Spasticity
Early Injection of Botulinum Toxin on Motor Function and Gait Pattern in Stroke Patients
Spasticity, muscle weakness, abnormal gait pattern are co-morbidities commonly seen in stroke patients. They cause disabled condition of patients in activities of daily life and functional performance, and also accidental falls…
- Trial name
- NCT01817816
- Testing
- Botox_A, Botox_B
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
Sleep Apnea
Muscle Strength Exercise and Sleep Apnea
Background: Obstructive sleep apnea is one of our common diseases and up to 80% of patients are estimated to be undiagnosed. Its main risk factors are overweight, age, male gender, menopause, small jaw, sedative medications /…
- Trial name
- NCT05320952
- Testing
- WellO2
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Prostate Hypertrophy, Renal Disease
Effect of Deep BLock on Intraoperative Surgical Conditions
Rationale: A deep neuromuscular block is often associated with improved surgical conditions especially in laparoscopic surgery. However, a deep block comes at the expense of a variety of items that may conflict with the use of a…
- Trial name
- BLISS (NCT01631149)
- Testing
- Surgical block (rocuronium; atracurium/mivacurium)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Leiden University Medical Center
Closed Femur Fracture
Rehabilitation Enhanced by Partial Arterial Inflow Restrictions
The Rehabilitation Enhanced by Partial Arterial Inflow Restriction (REPAIR) Study will be conducted in a patient population of individuals recovering from a traumatic diaphyseal fracture of the femur.
- Trial name
- REPAIR (NCT02746458)
- Testing
- Blood Flow Restriction, Delfi PTSII Tourniquet System
- Where
- 8 sites in United States
- Volunteers
- 219 people
- Sponsor
- Major Extremity Trauma Research Consortium
Anesthesia
Potential Role of Intravenous Lidocaine Versus Intravenous Ketamine for Pain Management in Fibromyalgia Patients
The aim of the study is to assess the efficacy of intravenous lidocaine versus intravenous ketamine in treatment of fibromyalgia patients.
- Trial name
- NCT06184958
- Testing
- Lidocaine group, Ketamine group
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Fibromyalgia
Gabapentin in Fibromyalgia Trial (GIFT)
This study will assess the safety and effectiveness of the drug gabapentin in reducing pain associated with primary fibromyalgia.
- Trial name
- NCT00057278
- Testing
- gabapentin
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Fibromyalgia, Rheumatoid Arthritis
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated…
- Trial name
- NCT05277025
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Florida
Stress Urinary Incontinence, Pelvic Organ Prolapse
Pelvic Floor Muscles and Success in the Surgical Treatment of Stress Urinary Incontinence and Pelvic Organ Prolapse
The aim of the study is evaluation of the efficiency of pelvic floor muscles in the context of surgical outcomes in the treatment of stress urinary incontinence and pelvic organ prolapse.
- Conditions
- Stress Urinary Incontinence, Pelvic Organ Prolapse, Pelvic Floor Disorders
- Trial name
- NCT04029168
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Żelazna Medical Centre, LLC
Pain, Postoperative, Anesthesia, Local
Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
This study aims to investigate the effect of transversus thoracis muscle plane block (TTP), using repeated boluses of ropivacaine via catheter, on postoperative pain and oxycodone consumption after elective cardiac surgery with…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- TTPcat (NCT04916418)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
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